Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Mara d'Onofrio"'
Autor:
Francesco Davide Naso, Krenare Bruqi, Valeria Manzini, Valerio Chiurchiù, Mara D’Onofrio, Ivan Arisi, Flavie Strappazzon
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Breast Cancer (BC) is one of the most common tumours, and is known for its ability to develop resistance to chemotherapeutic treatments. Autophagy has been linked to chemotherapeutic response in several types of cancer, highlighting its cont
Externí odkaz:
https://doaj.org/article/18b95df482b34b7490e2fdf2c2275611
Autor:
Francesco Taglino, Fabio Cumbo, Giulia Antognoli, Ivan Arisi, Mara D’Onofrio, Federico Perazzoni, Roger Voyat, Giulia Fiscon, Federica Conte, Marco Canevelli, Giuseppe Bruno, Patrizia Mecocci, Paola Bertolazzi, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background The recent advances in biotechnology and computer science have led to an ever-increasing availability of public biomedical data distributed in large databases worldwide. However, these data collections are far from being “standa
Externí odkaz:
https://doaj.org/article/cefe96765ab84bb99fd28a5ffa0fa506
Autor:
Ivan Arisi, Leonardo Malimpensa, Valeria Manzini, Rossella Brandi, Tommaso Gosetti di Sturmeck, Chiara D’Amelio, Sebastiano Crisafulli, Gina Ferrazzano, Daniele Belvisi, Francesca Malerba, Rita Florio, Esterina Pascale, Hermona Soreq, Marco Salvetti, Antonino Cattaneo, Mara D’Onofrio, Antonella Conte
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Background and objectivesMultiple sclerosis (MS) is a chronic, progressive neurological disease characterized by early-stage neuroinflammation, neurodegeneration, and demyelination that involves a spectrum of heterogeneous clinical manifestations in
Externí odkaz:
https://doaj.org/article/fd58ef36b5ed4df88fb3c4411a2e547d
Autor:
Alexia Tiberi, Nicola Maria Carucci, Giovanna Testa, Caterina Rizzi, Paola Pacifico, Giulia Borgonovo, Ivan Arisi, Mara D’Onofrio, Rossella Brandi, Wen-Biao Gan, Simona Capsoni, Antonino Cattaneo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Nerve growth factor (NGF) is critical for neuronal physiology during development and adulthood. Despite the well-recognized effect of NGF on neurons, less is known about whether NGF can actually affect other cell types in the central nervous system (
Externí odkaz:
https://doaj.org/article/70f8d11545334a57a350abfeb5c510d8
Autor:
Andrea Margari, Anna Grazia Monteduro, Silvia Rizzato, Loredana Capobianco, Alessio Crestini, Roberto Rivabene, Paola Piscopo, Mara D’Onofrio, Valeria Manzini, Giuseppe Trapani, Alessandra Quarta, Giuseppe Maruccio, Carmelo Ventra, Luigi Lieto, Adriana Trapani
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1827 (2022)
(1) Backgrond: Considering the positive effects of citicoline (CIT) in the management of some neurodegenerative diseases, the aim of this work was to develop CIT-Loaded Solid Lipid Nanoparticles (CIT-SLNs) for enhancing the therapeutic use of CIT in
Externí odkaz:
https://doaj.org/article/8a9e5b2a19204c21b021c5037f274cd1
Autor:
Simona Capsoni, Ivan Arisi, Francesca Malerba, Mara D’Onofrio, Antonino Cattaneo, Enrico Cherubini
Publikováno v:
Brain Sciences, Vol 12, Iss 6, p 783 (2022)
GABA, the main inhibitory neurotransmitter in the adult brain, depolarizes and excites immature neurons because of an initially higher intracellular chloride concentration [Cl−]i due to the delayed expression of the chloride exporter KCC2 at birth.
Externí odkaz:
https://doaj.org/article/07154fcfa52a4a518b1d838b47c8e2a4
Autor:
Marco Terrigno, Irene Busti, Claudia Alia, Marta Pietrasanta, Ivan Arisi, Mara D'Onofrio, Matteo Caleo, Federico Cremisi
Publikováno v:
Stem Cell Reports, Vol 10, Iss 3, Pp 1016-1029 (2018)
Summary: The capability of generating neural precursor cells with distinct types of regional identity in vitro has recently opened new opportunities for cell replacement in animal models of neurodegenerative diseases. By manipulating Wnt and BMP sign
Externí odkaz:
https://doaj.org/article/3b624b84a0de48358054b3a81b06bac3
Autor:
Rossella Brandi, Marietta Fabiano, Corinna Giorgi, Ivan Arisi, Federico La Regina, Francesca Malerba, Sabrina Turturro, Andrea Ennio Storti, Flavia Ricevuti, Susanna Amadio, Cinzia Volontè, Simona Capsoni, Raffaella Scardigli, Mara D’Onofrio, Antonino Cattaneo
Publikováno v:
Cells, Vol 10, Iss 2, p 405 (2021)
In the brain, the neurotrophin Nerve growth factor (NGF) regulates not only neuronal survival and differentiation, but also glial and microglial functions and neuroinflammation. NGF is known to regulate oligodendrogenesis, reducing myelination in the
Externí odkaz:
https://doaj.org/article/22a2f046e12a4c7b96722c524e694f39
Autor:
Michele Bertacchi, Giuseppe Lupo, Luca Pandolfini, Simona Casarosa, Mara D’Onofrio, Roger A. Pedersen, William A. Harris, Federico Cremisi
Publikováno v:
Stem Cell Reports, Vol 5, Iss 4, Pp 532-545 (2015)
Retinal progenitors are initially found in the anterior neural plate region known as the eye field, whereas neighboring areas undertake telencephalic or hypothalamic development. Eye field cells become specified by switching on a network of eye field
Externí odkaz:
https://doaj.org/article/3e650a27161a4010b717039edbea4010
Autor:
Manuela Caputo, Alessio Balzerano, Ivan Arisi, Mara D'Onofrio, Rossella Brandi, Silvia Bongiorni, Stefano Brancorsini, Mattia Frontini, Luca Proietti-De-Santis
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172399 (2017)
The DNA repair protein Cockayne syndrome group B (CSB) has been recently identified as a promising anticancer target. Suppression, by antisense technology, of this protein causes devastating effects on tumor cells viability, through a massive inducti
Externí odkaz:
https://doaj.org/article/5ada6a63f88243899d7d00ad3620186f