Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mara Zippoli"'
Autor:
Daniela Iaconis, Licia Bordi, Giulia Matusali, Carmine Talarico, Candida Manelfi, Maria Candida Cesta, Mara Zippoli, Francesca Caccuri, Antonella Bugatti, Alberto Zani, Federica Filippini, Laura Scorzolini, Marco Gobbi, Marten Beeg, Arianna Piotti, Monica Montopoli, Veronica Cocetta, Silvia Bressan, Enrico M. Bucci, Arnaldo Caruso, Emanuele Nicastri, Marcello Allegretti, Andrea R. Beccari
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-9 (2022)
Abstract The new coronavirus SARS-CoV-2 is the causative agent of the COVID-19 pandemic, which so far has caused over 6 million deaths in 2 years, despite new vaccines and antiviral medications. Drug repurposing, an approach for the potential applica
Externí odkaz:
https://doaj.org/article/9f7ad91081cf4ba8bb1f706204ee8be2
Autor:
Mara Zippoli, Anna Ruocco, Rubina Novelli, Francesca Rocchio, Martina Sara Miscione, Marcello Allegretti, Maria Candida Cesta, Pier Giorgio Amendola
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Tumor drug resistance is a multifactorial and heterogenous condition that poses a serious burden in clinical oncology. Given the increasing incidence of resistant tumors, further understanding of the mechanisms that make tumor cells able to escape an
Externí odkaz:
https://doaj.org/article/a5c0f02a97804544a38b0e682ab151b6
Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky Gut
Autor:
Michele d’Angelo, Laura Brandolini, Mariano Catanesi, Vanessa Castelli, Cristina Giorgio, Margherita Alfonsetti, Mara Tomassetti, Mara Zippoli, Elisabetta Benedetti, Maria Candida Cesta, Sandro Colagioia, Pasquale Cocchiaro, Annamaria Cimini, Marcello Allegretti
Publikováno v:
Cells, Vol 12, Iss 5, p 728 (2023)
The intestinal barrier is the main contributor to gut homeostasis. Perturbations of the intestinal epithelium or supporting factors can lead to the development of intestinal hyperpermeability, termed “leaky gut”. A leaky gut is characterized by l
Externí odkaz:
https://doaj.org/article/7a889804ed8b45f88df7c91cc1ff6d7a
Autor:
Maria Candida Cesta, Mara Zippoli, Carolina Marsiglia, Elizabeth Marie Gavioli, Flavio Mantelli, Marcello Allegretti, Robert A. Balk
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Severe Acute Respiratory Syndrome Coronavirus—2 (SARS CoV-2) has resulted in the global spread of Coronavirus Disease 2019 (COVID-19) and an increase in complications including Acute Respiratory Distress Syndrome (ARDS). Due to the lack of therapeu
Externí odkaz:
https://doaj.org/article/ce587c888c974e3a8a88e67c44cf11a5
Autor:
Cristina Giorgio, Mara Zippoli, Pasquale Cocchiaro, Vanessa Castelli, Giustino Varrassi, Andrea Aramini, Marcello Allegretti, Laura Brandolini, Maria Candida Cesta
Publikováno v:
Biomedicines, Vol 9, Iss 4, p 399 (2021)
The complement system is a key component of innate immunity since it plays a critical role in inflammation and defense against common pathogens. However, an inappropriate activation of the complement system is involved in numerous disorders, includin
Externí odkaz:
https://doaj.org/article/f755010812924628b49f5b5318d75933
Publikováno v:
Pain and Therapy. 11:1113-1136
Chemotherapy-induced peripheral neuropathy (CIPN) is the most common neurologic complication of chemotherapy, resulting in symptoms like pain, sensory loss, and numbness in the hands and feet that cause lots of uneasiness in patients with cancer. The
Autor:
Maria Candida Cesta, Mara Zippoli, Carolina Marsiglia, Elizabeth M. Gavioli, Giada Cremonesi, Akram Khan, Flavio Mantelli, Marcello Allegretti, Robert Balk
Publikováno v:
European journal of immunologyReferences.
Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition with a dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID-19) pandemic. Neutrophils play a vital role in the immunopathology of severe
Autor:
Licia Bordi, Daniela Iaconis, Giulia Matusali, Maria Candida Cesta, Enrico M. Bucci, Laura Scorzolini, Mara Zippoli, Marcello Allegretti, Emanuele Nicastri, Carmine Talarico, Francesca Caccuri, Andrea R. Beccari, Arnaldo Caruso, Candida Manelfi
The new coronavirus that emerged, called SARS-CoV-2, is the causative agent of the COVID-19 pandemic. The identification of potential drug candidates that can rapidly enter clinical trials for the prevention and treatment of COVID-19 is an urgent nee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c73a61c6c64742f385eaa0d8bcbed9f8
https://doi.org/10.1101/2021.10.22.465294
https://doi.org/10.1101/2021.10.22.465294
Autor:
Pasquale Cocchiaro, Andrea Aramini, Vanessa Castelli, Cristina Giorgio, Laura Brandolini, Maria Candida Cesta, Giustino Varrassi, Marcello Allegretti, Mara Zippoli
Publikováno v:
Biomedicines
Biomedicines, Vol 9, Iss 399, p 399 (2021)
Biomedicines, Vol 9, Iss 399, p 399 (2021)
The complement system is a key component of innate immunity since it plays a critical role in inflammation and defense against common pathogens. However, an inappropriate activation of the complement system is involved in numerous disorders, includin
Autor:
Steve P. Watson, Nicola Bevan, Kitty Moores, Joanne Philp, Claudette Mookherjee, Val Piercy, Mara Zippoli, Chris A. Smethurst, Amanda Emmons, Carl Brooks, Simon Peace, Peter J. Gough
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:7252-7255
Optimisation of a series of biaryl sulphonamides resulted in the identification of compound 14 [corrected] which demonstrated dose-dependent and strain-specific inhibition of monocyte recruitment in a thioglycollate-induced peritonitis model of infla