Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mara Vinci"'
Autor:
Giada Del Baldo, Andrea Carai, Rachid Abbas, Antonella Cacchione, Mara Vinci, Valentina Di Ruscio, Giovanna Stefania Colafati, Sabrina Rossi, Francesca Diomedi Camassei, Nicola Maestro, Sara Temelso, Giulia Pericoli, Emmanuel De Billy, Isabella Giovannoni, Alessia Carboni, Martina Rinelli, Emanuele Agolini, Alan Mackay, Chris Jones, Silvia Chiesa, Mario Balducci, Franco Locatelli, Angela Mastronuzzi
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: Diffuse intrinsic pontine glioma (DIPG) is a fatal disease with a median overall survival (OS) of less than 12 months after diagnosis. Radiotherapy (RT) still remains the mainstay treatment. Several other therapeutic strategies have been
Externí odkaz:
https://doaj.org/article/6424a769c3b241c4b0d3dc614eda6a04
Autor:
Yura Grabovska, Sara Temelso, Chris Jones, Valeria Molinari, Jyoti S. Choudhary, Alan Mackay, Mara Vinci, Ketty Kessler, Lu Yu, Mariella G. Filbin, Andrea Sottoriva, Haider Tari, Ilon Liu, Erika Yara-Romero, David Castel, Anna Burford
SUMMARYDIPG are characterised by histone H3K27M mutations, resulting in global loss of the repressive mark H3K27me3, although certain key loci are retained. We recently identified subclonal loss-of-function mutations in the H4 lysine methyltransferas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::718b5d1510f90b7f737cbf9773c2d703
https://doi.org/10.1101/2021.07.19.452493
https://doi.org/10.1101/2021.07.19.452493
Autor:
Chris Jones, Natacha Entz-Werle, Paula Proszek, Angela Mastronuzzi, Alan Mackay, Daniel Rodriguez, Giulia Pericoli, Darren Hargrave, Sara Temelso, Matthew Clarke, Mike Hubank, Mara Vinci, Paul S. Morgan, Elisa Izquierdo, Fernando Carceller, Lynley V. Marshall, Tim Jaspan, Diana Carvalho, Simon Bailey, Gilles Vassal, Zdenek Pavelka, Birgitta Lannering, Jacques Grill
Publikováno v:
Neuro-oncology Advances
Background The use of liquid biopsy is of potential high importance for children with high grade (HGG) and diffuse midline gliomas (DMG), particularly where surgical procedures are limited, and invasive biopsy sampling not without risk. To date, howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db39dc2df706f8cce7894ffb1219e71a
https://doi.org/10.1093/noajnl/vdab013
https://doi.org/10.1093/noajnl/vdab013
Autor:
Michael Farrell, Ketty Kessler, Jessica K.R. Boult, Safa Al-Sarraj, Fernando Carceller, Evelina Miele, Alan Mackay, Mariama Fofana, Leslie R. Bridges, Ranj Bhangoo, Rebecca Rogers, Paula Proszek, Lynley V. Marshall, Matthew Clarke, Janat Fazal Salom, Bassam Dabbous, Franco Locatelli, Christopher J. Lord, Chris Jones, Sucheta Vaidya, John Caird, Michelle Monje, Elisa Izquierdo, Angel M. Carcaboso, Andrea Carai, Samantha Hettige, Sara Temelso, Yura Grabovska, Christopher Chandler, Darach Crimmins, Lynn Bjerke, Simon R. Stapleton, Mara Vinci, Jane Pears, Angela Mastronuzzi, Giulia Pericoli, Kathryn R. Taylor, Elisabet F Potente, Simon P. Robinson, Anna Burford, Andrew J. Martin, Mike Hubank, Timothy E.G. Hassall, Bassel Zebian, Henry Mandeville, Jane Cryan, Helen N. Pemberton, Andrew S. Moore, Robert Johnston, Nagore G. Olaciregui, Valeria Molinari, Diana Carvalho
Paediatric high grade glioma and diffuse midline glioma (including DIPG) are comprised of multiple biological and clinical subgroups, the majority of which urgently require novel therapies. Patient-derivedin vitroprimary cell cultures represent poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c89e3a42fb668fa43263a196c0ca138
https://doi.org/10.1101/2020.12.29.424674
https://doi.org/10.1101/2020.12.29.424674
Autor:
Andrew J. Martin, Elizabeth Y. Qin, Ofelia Cruz, Leslie R. Bridges, Jaume Mora, Andrew S. Moore, Natacha Entz-Werle, Henry Mandeville, Carmen de Torres, Kathryn R. Taylor, Sucheta Vaidya, Christopher J. Lord, Angel M. Carcaboso, Lynley V. Marshall, Valeria Molinari, Ketty Kessler, Diana Carvalho, Mariona Suñol, Dorra H'mida-Ben Brahim, Anna Burford, Wendy J. Ingram, Tim Forshew, Mara Vinci, Michelle Monje, Alice Gutteridge, Christopher Chandler, Ho Keung Ng, Saoussen Trabelsi, Matthew Clarke, Sergey V. Popov, Helen Pemberton, Chris Jones, Safa Al-Sarraj, Stergios Zacharoulis, Alan Mackay
Publikováno v:
Nature medicine
NATURE MEDICINE
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
NATURE MEDICINE
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
The failure to develop effective therapies for paediatric glioblastoma (pGBM) and diffuse intrinsic pontine glioma (DIPG) is in part due to their intrinsic heterogeneity. We aimed to quantitatively map assess the extent to which this was present in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c676260dd12a1b533e825e93c925fb5e
http://europepmc.org/articles/PMC6086334
http://europepmc.org/articles/PMC6086334
Autor:
Anna Burford, Ketty Kessler, Sara Temelso, Lynn Bjerke, Mara Vinci, Alan Mackay, Valeria Molinari, Chris Jones
Diffuse intrinsic pontine glioma (DIPG) are incurable childhood brain tumours marked by alterations in histone 3 in the form of somatic K27M mutations and loss of H3K27 trimethylation (H3K27me3). These highly aggressive tumours display extensive intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848467ba6a3d37e766c2b047ce93c85d
https://europepmc.org/articles/PMC6477248/
https://europepmc.org/articles/PMC6477248/
Autor:
Mara Vinci, Carmen de Torres, Sergey Popov, Valeria Molinari, Elizabeth Y. Qin, Angel M. Carcaboso, Jaume Mora, Kathryn R. Taylor, Alan Mackay, Michelle Monje, Chris Jones, Ofelia Cruz, Mariona Suñol, Anna Burford, Andrew S. Moore, Wendy J. Ingram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d58ce28e25757e5166b7087a2c4e39
https://europepmc.org/articles/PMC4903445/
https://europepmc.org/articles/PMC4903445/
Autor:
Nils Hecht, Johannes Woitzik, Pablo Peña-Tapia, Georges von Degenfeld, Mara Vinci, Peter Vajkoczy
Publikováno v:
Journal of Neuroscience Methods. 201:61-66
An encephalomyosynangiosis (EMS) is a temporal muscle graft that is placed onto the surface of the brain to serve as a source for collateral vessel growth for brain revascularization in patients with Moyamoya Disease (MMD). To facilitate an EMS in pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae13e26f3ecc31031713625b82f3118
https://doi.org/10.1016/j.jneumeth.2011.07.011
https://doi.org/10.1016/j.jneumeth.2011.07.011
Autor:
Lorenzo Lattavo, Giovanna Stefania Colafati, Antonella Cacchione, Ioan Paul Voicu, Chiara Carducci, Maria Camilla Rossi Espagnet, Andrea Carai, Antonio Napolitano, Mara Vinci, Paolo Tomà, Angela Mastronuzzi
Publikováno v:
Neuro-Oncology. 20:i173-i173
PURPOSE: To investigate whether diffusion kurtosis imaging (DKI) can be helpful in differentiating low- and high-grade gliomas (LGG and HGG respectively) in pediatric patients. MATERIALS AND METHODS: After obtaining informed consent, thirty-two conse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de34c00f383bcead7d4415af0888b2f8
https://doi.org/10.1093/neuonc/noy059.658
https://doi.org/10.1093/neuonc/noy059.658
Publikováno v:
International Journal of Cancer. 124:1293-1300
Current clinical protocols favor a combination of antiangiogenic/antivascular compounds with classical chemotherapy. However, it remains unclear to what extent an antiangiogenic/antivascular therapy influences the delivery of chemotherapy. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf543714f0b7115c53256330c09ab4fc
https://doi.org/10.1002/ijc.24019
https://doi.org/10.1002/ijc.24019