Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Mara Swaim"'
1
A Critical Role for the Protein Apoptosis Repressor With Caspase Recruitment Domain in Hypoxia-Induced Pulmonary Hypertension
Autor: Shehzin Mozammel, Priya Kesari, Chang Fu Peng, Ari L. Zaiman, Hunter C. Champion, Michael T. Crow, Mara Swaim, Rachel L. Damico, D. Clark Files, Hazim El-Haddad, Alan Thoms-Chesley, Alan C. Myers, Laura Johnston, Marc K. Halushka, Richard N. Kitsis, Paul M. Hassoun, Larissa A. Shimoda
Publikováno v: Circulation. 124:2533-2542
Background— Pulmonary hypertension (PH) is a lethal syndrome associated with the pathogenic remodeling of the pulmonary vasculature and the emergence of apoptosis-resistant cells. Apoptosis repressor with caspase recruitment domain (ARC) is an inhi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ce4e5b8443be4e0ce68e48b76185f35
https://doi.org/10.1161/circulationaha.111.034512
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2
MicroRNAs Regulate Ocular Neovascularization
Autor: Yangjian Chen, Bing Xie, Peter A. Campochiaro, Xiao ru Yang, Ji Kui Shen, Sean F. Hackett, Mara Swaim
Publikováno v: Molecular Therapy. 16(7):1208-1216
In this study, we used ischemia-induced retinal neovascularization (NV) as a model to investigate the possible role of microRNAs in a clinically important disease process. Microarray analysis demonstrated seven microRNAs (miR-106a, -146, -181, -199a,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275b0244057245916317aef29d144bc2
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6
An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization
Autor: Peter A. Campochiaro, Aling Dong, Mara Swaim, Sean F. Hackett, Susanne Worpenberg, Lorenza Wyder, Bing Xie, Samuel Barbieri, Jikui Shen
Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 22(8)
Proteins with a disintegrin and a metalloproteinase domain (ADAMs) are a family of membrane-bound proteinases that bind integrins through their disintegrin domain. In this study, we have found modest expression of ADAM15 in pericytes in normal retina
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9ea326fba7ccfafed17b8d9d33328a
https://pubmed.ncbi.nlm.nih.gov/18381816
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7
In vivo immunostaining demonstrates macrophages associate with growing and regressing vessels
Autor: Aling Dong, Mara Swaim, Jikui Shen, Bing Xie, Sean F. Hackett, Peter A. Campochiaro
Publikováno v: Investigative ophthalmologyvisual science. 48(9)
Purpose The purpose of this study was to identify ways to improve qualitative and quantitative assessments of retinal vessels and neovascularization (NV). Methods At postnatal day (P) 17, mice with oxygen-induced ischemic retinopathy were injected in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c76cd0ae86b5074a9bb767538140d1d
https://pubmed.ncbi.nlm.nih.gov/17724225
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8
Differential Sensitivity of Cones to Iron-Mediated Oxidative Damage
Autor: Robert C. A. Symons, Wei-Hong Xiao, Jikui Shen, Peter A. Campochiaro, Keiichi Komeima, Brian S. Rogers, Shu Kachi, Yuan Yuan Gong, Mara Swaim
Publikováno v: Investigative Opthalmology & Visual Science. 48:438
PURPOSE. In this study, the hypothesis that increased intraocular levels of iron cause oxidative damage to the retina was tested. METHODS. Adult C57BL/6 mice were given an intravitreous injection of saline or 0.10, 0.25, or 0.50 mM FeSO4. Scotopic el
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0088dad7bad9b4ee78ddac002b43e7f
https://doi.org/10.1167/iovs.06-0528
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Plný text Recenzováno Digitální knihovna AV ČR
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