Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mara Sanapo"'
Autor:
Tatiana Gianni, Valerio Leoni, Mara Sanapo, Federico Parenti, Daniela Bressanin, Catia Barboni, Anna Zaghini, Gabriella Campadelli-Fiume, Andrea Vannini
Publikováno v:
Viruses, Vol 13, Iss 9, p 1747 (2021)
We report on the efficacy of the non-attenuated HER2-retargeted oHSV named R-337 against the immunologically hot CT26-HER2 tumor, and an insight into the basis of the immune protection. Preliminarily, we conducted an RNA immune profiling and immune c
Externí odkaz:
https://doaj.org/article/c2e0cfeece034633a0c106f8b9668105
Autor:
Valerio Leoni, Andrea Vannini, Valentina Gatta, Julie Rambaldi, Mara Sanapo, Catia Barboni, Anna Zaghini, Patrizia Nanni, Pier-Luigi Lollini, Costanza Casiraghi, Gabriella Campadelli-Fiume
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007209 (2018)
Oncolytic herpes simplex viruses (oHSVs) showed efficacy in clinical trials and practice. Most of them gain cancer-specificity from deletions/mutations in genes that counteract the host response, and grow selectively in cancer cells defective in anti
Externí odkaz:
https://doaj.org/article/941a02ea5ec54fb1bb91d83ff00a6408
Autor:
Gabriella Campadelli-Fiume, Anna Zaghini, Valerio Leoni, Tatiana Gianni, Mara Sanapo, Federico Parenti, Andrea Vannini, Daniela Bressanin, Catia Barboni
Publikováno v:
Viruses, Vol 13, Iss 1747, p 1747 (2021)
Viruses
Volume 13
Issue 9
Viruses
Volume 13
Issue 9
We report on the efficacy of the non-attenuated HER2-retargeted oHSV named R-337 against the immunologically hot CT26-HER2 tumor, and an insight into the basis of the immune protection. Preliminarily, we conducted an RNA immune profiling and immune c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf5166810ac72707ff9d57297bdd49c
https://www.mdpi.com/1999-4915/13/9/1747
https://www.mdpi.com/1999-4915/13/9/1747
Autor:
Catia Barboni, Anna Zaghini, Valerio Leoni, Tatiana Gianni, Gabriella Campadelli-Fiume, Andrea Vannini, Paolo Malatesta, Mara Sanapo
Publikováno v:
Proceedings of the National Academy of Sciences. 116:20141-20150
Tumors utilize a number of effective strategies, including the programmed death 1/PD ligand 1 (PD-1/PD-L1) axis, to evade immune-mediated control of their growth. PD-L1 expression is mainly induced by IFN receptor signaling or constitutively induced.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567face76e4eecfb81e8e719ab70dca3
https://doi.org/10.1073/pnas.1901931116
https://doi.org/10.1073/pnas.1901931116
Autor:
Giovanna Lattanzi, Elisa Schena, Giuseppe Sarli, Gianluca Storci, Elisabetta Mattioli, Davide Andrenacci, Anna Zaghini, Massimiliano Bonafè, Patrizia Sabatelli, Catia Barboni, Valeria Pellegrino, Vittoria Cenni, Cristina Capanni, Maria Rosaria D'Apice, Stefano Squarzoni, Mara Sanapo, Fabio Baruffaldi, Anna Festa
Publikováno v:
Aging Cell
Hutchinson–Gilford progeria syndrome (HGPS) causes premature aging in children, with adipose tissue, skin and bone deterioration, and cardiovascular impairment. In HGPS cells and mouse models, high levels of interleukin‐6, an inflammatory cytokin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b7eca7ce165131ffcc71ddcadaf471
http://hdl.handle.net/11585/795517
http://hdl.handle.net/11585/795517
Autor:
Catia Barboni, Anna Zaghini, Tatiana Gianni, Valentina Gatta, Andrea Vannini, Giorgia Giordani, Mara Sanapo, Gabriella Campadelli-Fiume, Valerio Leoni
Publikováno v:
Cancers, Vol 13, Iss 266, p 266 (2021)
Cancers
Cancers
Simple Summary The onco-immunotherapeutic viruses, among which stand the onco-immunotherapeutic herpes simplex viruses, have gained renewed interest due to their ability to unlock the potential of checkpoint inhibitors in preclinical and clinical set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0f33aebacb7d88bbf7dadf5f0380ce
https://www.mdpi.com/2072-6694/13/2/266
https://www.mdpi.com/2072-6694/13/2/266
Autor:
Paolo Malatesta, Valerio Leoni, Andrea Vannini, Gabriella Campadelli-Fiume, Mara Sanapo, Catia Barboni, Tatiana Gianni, Anna Zaghini
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The PD-1/PD-L1 axis is a master player in the tumor immune evasion strategy. Checkpoint inhibitors, including anti–PD-1/PD-L1, are revolutionizing cancer immunotherapy. There is intense interest in dissecting their regulation and impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af8f7228a779efd2eb8f15a90662760
https://pubmed.ncbi.nlm.nih.gov/31527243
https://pubmed.ncbi.nlm.nih.gov/31527243
Autor:
Giovanna Lattanzi, Francesco Prisco, Mara Sanapo, Massimiliano Baleani, Elisa Schena, Catia Barboni, Cristina Capanni, Valeria Pellegrino, Anna Festa, Michela Murdocca, Roberta Fognani, Stefano Squarzoni, Alessia Diana, Orlando Paciello, Anna Zaghini, Maria Rosaria D'Apice, Serenella Papparella, Manuela Loi, Rosaria Mecca, Nikolina Linta, Giuseppe Sarli, Julie Rambaldi, Fabio Baruffaldi
Publikováno v:
Experimental gerontology. 130
The transgenic LmnaG609G progeric mouse represents an outstanding animal model for studying the human Hutchinson-Gilford Progeria Syndrome (HGPS) caused by a mutation in the LMNA gene, coding for the nuclear envelope protein Lamin A/C, and, as an imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd44e700c2d6a7f78966d1dbc3585efc
https://pubmed.ncbi.nlm.nih.gov/31794853
https://pubmed.ncbi.nlm.nih.gov/31794853
Autor:
Catia Barboni, Mara Sanapo, Gabriella Campadelli-Fiume, Pier Luigi Lollini, Valentina Gatta, Anna Zaghini, Valerio Leoni, Julie Rambaldi, Costanza Casiraghi, Patrizia Nanni, Andrea Vannini
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007209 (2018)
PLoS Pathogens
PLoS Pathogens
Oncolytic herpes simplex viruses (oHSVs) showed efficacy in clinical trials and practice. Most of them gain cancer-specificity from deletions/mutations in genes that counteract the host response, and grow selectively in cancer cells defective in anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778cd88a8cd269baaa3bd6093f9b93de
https://doi.org/10.1371/journal.ppat.1007209
https://doi.org/10.1371/journal.ppat.1007209