Výsledky vyhledávání - "Mara S. Trebucobich"

The urinary excretion of an organic anion transporter as an early biomarker of methotrexate-induced kidney injury

Autor: Anabel Brandoni, Adriana M. Torres, Patricia Buszniez, María Julia Severin, Mara S. Trebucobich

Publikováno v: Toxicology research. 5(2)

Methotrexate (MTX) belongs to a group of medicines known as antimetabolites. It is commonly used in the treatment of malignant diseases and is prescribed in autoimmune and chronic inflammatory disorders. Along with its effective therapeutic power, MT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a976d94fb85ce5c9a4913cb721e577
https://pubmed.ncbi.nlm.nih.gov/30090367

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Amelioration of mercury nephrotoxicity after pharmacological manipulation of organic anion transporter 1 (Oat1) and multidrug associated resistance protein 2 (Mrp2) with furosemide

Autor: Tania Romina Stoyanoff, María Herminia Hazelhoff, Adriana M. Torres, Alberto A. Chevalier, Mara S. Trebucobich

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Inorganic mercury is a major environmental contaminant. The primary site of mercuryinduced injury is the kidney due to the uptake of Hg(2+) -conjugated organic anions in the proximal tubule, primary across the organic anion transporter 1 (Oat1) at th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd4e9bc1ce1bbdf09083e82af8c2af7
http://pubs.rsc.org/en/Content/ArticleLanding/2015/TX/C5TX00100E#!divAbstract

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Protein expression of kidney and liver bilitranslocase in rats exposed to mercuric chloride-a potential tissular biomarker of toxicity

Autor: Sabina Passamonti, María Herminia Hazelhoff, Alberto A. Chevalier, Mara S. Trebucobich, Adriana M. Torres, Anabel Brandoni

Bilitranslocase (BTL) is a plasma membrane carrier that transports organic anions of physiological and pharmacological interest. It is expressed in basolateral plasma membrane of kidney and liver. BTL has been recently described as a marker of transi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78cb2de658df17d2fa0fd7fc912aab87
http://www.sciencedirect.com/science/article/pii/S0378427413014288

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