Výsledky vyhledávání - "Mara R. Torrisi"

Data from Microvesicle Cargo of Tumor-Associated MUC1 to Dendritic Cells Allows Cross-presentation and Specific Carbohydrate Processing

Autor: Marianna Nuti, Mara R. Torrisi, Joy M. Burchell, Pierluigi Benedetti Panici, Hans H. Wandall, Filippo Bellati, Morena Antonilli, Ilaria G. Zizzari, Federico Battisti, Chiara Napoletano, Francesca Belleudi, Hassan Rahimi, Aurelia Rughetti

Tumor-associated glycoproteins are a group of antigens with high immunogenic interest: The glycoforms generated by the aberrant glycosylation are tumor-specific and the novel glycoepitopes exposed can be targets of tumor-specific immune responses. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0cff61bdd63d8924a51210589dbd862
https://doi.org/10.1158/2326-6066.c.6548000.v1

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Supplemental Figure 1: HLAII-DR molecule accumulates at the periphery of DCs after 12 hours incubation from Microvesicle Cargo of Tumor-Associated MUC1 to Dendritic Cells Allows Cross-presentation and Specific Carbohydrate Processing

Cellular distribution of HLAII-DR molecules in iDCs was visualized after 2 or 12 hours from cell harvesting and incubation at 37{degree sign}C (columns 1 and 2, respectively) by immunofluorescence staining by Apotome module employing the anti-HLA-DR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10eb20edec3e69b24ee9d04fb8629971
https://doi.org/10.1158/2326-6066.22535987.v1

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Supplementary Figure 1 - PDF file - 42K from Microvesicle Cargo of Tumor-Associated MUC1 to Dendritic Cells Allows Cross-presentation and Specific Carbohydrate Processing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef0df1e5652d130a941b67333ad338a
https://doi.org/10.1158/2326-6066.22535981

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Supplemental Figure 2: Characterization of MUC1-DG75 transfectant cell line and of the MUC1-DG75-MVs. from Microvesicle Cargo of Tumor-Associated MUC1 to Dendritic Cells Allows Cross-presentation and Specific Carbohydrate Processing

A, MUC1 glycoform expression of MUC1-DG75 transfectant detected by flow cytometry employing anti-MUC1 glycoform specific MoAbs. Only the ST-MUC1 glycoform, (MoAb MYE12), is expressed on the surface of transfectant cells. B, MUC1 distribution on MVs s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c56cc8f8670d4a77c452ca9e806542
https://doi.org/10.1158/2326-6066.22535984.v1

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