Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mara Molkentin"'
Autor:
Gundula Thiel, Olga Blau, Igor Wolfgang Blau, Thomas Burmeister, Seval Türkmen, Annette Sindram, Stefan Mundlos, Eckhard Thiel, Claudia D. Baldus, Florian Nolte, Wolf-Karsten Hofmann, Mara Molkentin, Ulrich Keilholz, Ouidad Benlasfer, Elke Schümann
Publikováno v:
Blood. 118:5583-5592
Mesenchymal stromal cells (MSCs) are an essential cell type of the hematopoietic microenvironment. Concerns have been raised about the possibility that MSCs undergo malignant transformation. Several studies, including one from our own group, have sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3baec786f58fe96c62df3179f162cbdb
https://doi.org/10.1182/blood-2011-03-343467
https://doi.org/10.1182/blood-2011-03-343467
Autor:
Aline Renneville, Anja Möricke, Larisa Fechina, Martin Krzywinski, M. De Braekeleer, Eric Delabesse, Theodor Dingermann, L Lo Nigro, Shai Izraeli, Thomas Burmeister, Christian Meyer, Hélène Cavé, Jan Trka, R. Ben Abdelali, Julia Hofmann, Brian V. Balgobind, Mara Molkentin, U zur Stadt, G te Kronnie, L. Trakhtenbrot, Tomasz Szczepański, M. P. de Oliveira, D. Ilencikova, Sabine Strehl, Elizabeth Macintyre, Emmanuelle Clappier, E De Braekeleer, Beat W. Schäfer, Rolf Marschalek, Renate Panzer-Grümayer, Eric Kowarz, Eigil Kjeldsen, Jan Zuna, Cristina N. Alonso, Bernd Gruhn, M M van den Heuvel-Eibrink, Andrea Teigler-Schlegel, Li Chong Chan, J J M van Dongen, Ulrike Koehl, Jochen Harbott, Martin Schrappe, H B Beverloo, Susanne Schnittger, Olaf Heidenreich, Grigory Tsaur, Jürgen Krauter, T. Klingebiel, Dean A. Lee, C Eckert, Rosemary Sutton, Sze-Fai Yip
Publikováno v:
Leukemia, 23, 1490-1499. Nature Publishing Group
Chromosomal rearrangements of the human MLL gene are associated with high-risk pediatric, adult and therapy-associated acute leukemias. These patients need to be identified, treated appropriately and minimal residual disease was monitored by quantita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939cc22122a0b6e8e400808337706039
https://doi.org/10.1038/leu.2009.33
https://doi.org/10.1038/leu.2009.33
Autor:
Thomas Burmeister, Richard Reinhardt, Eckhard Thiel, Mara Molkentin, Nicola Gökbuget, Stefan Schwartz, Dieter Hoelzer
Publikováno v:
Molecular oncology. 7(4)
The chromosomal translocation t(8;14)(q24;q32) with juxtaposition of MYC to enhancer elements in the immunoglobulin heavy chain ( IGH ) gene locus is the genetic hallmark of the majority of Burkitt lymphoma and a subset of Diffuse large B-cell lympho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05c0b214372cd444beb3f463652f9e0
https://pubmed.ncbi.nlm.nih.gov/23673335
https://pubmed.ncbi.nlm.nih.gov/23673335
Autor:
Nils Lachmann, Claus Meyer, Gunnar Lohm, Stefan Schwartz, Thomas Burmeister, Lutz Uharek, Mara Molkentin, Rolf Marschalek, Birte Friedrichs, Jörg Beyer, Carola Tietze-Bürger, Igor Wolfgang Blau
Publikováno v:
Experimental Hematology & Oncology, Vol 1, Iss 1, p 6 (2012)
Experimental Hematology & Oncology
Experimental Hematology & Oncology
This report describes the clinical courses of two acute myeloid leukemia patients. Both had MLL translocations, the first a t(10;11)(p11.2;q23) with MLL-AF10 and the second a t(11;19)(q23;p13.1) with MLL-ELL fusion. They achieved a clinical remission
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2992dd9035b63207640bda387a0b66ae
https://doi.org/10.1186/2162-3619-1-6
https://doi.org/10.1186/2162-3619-1-6
Autor:
Mathias Riehn, Mara Molkentin, Richard Reinhardt, Eva Klopocki, Thomas Burmeister, Seval Türkmen
Publikováno v:
Genes, chromosomescancer. 50(6)
Abnormalities of the long arm of chromosome 6 are a common feature in various B-cell malignancies. In most cases, the genes involved have not yet been clearly identified. We have molecularly characterized the recently established Burkitt lymphoma cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0984d7daedd3cbfe9f254d53d29aa1
https://pubmed.ncbi.nlm.nih.gov/21412927
https://pubmed.ncbi.nlm.nih.gov/21412927
Autor:
Björn Schneider, Eckhard Thiel, Mara Molkentin, Rolf Marschalek, Thomas Burmeister, Julia Hofmann, Richard Reinhardt, Claus Meyer, Nicola Gökbuget, Eric Kowarz, Dieter Hoelzer, Thorsten Raff, Stefan Schwartz
Publikováno v:
Blood. 113(17)
MLL translocations in adult B-cell precursor (BCP) acute lymphoblastic leukemia (ALL) are largely restricted to the immature CD10− immunophenotypes. MLL-AF4 is known to be the most frequent fusion transcript, but the exact frequencies of MLL aberra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69429851d73c5f98a80f2f420e990ce5
https://pubmed.ncbi.nlm.nih.gov/19144982
https://pubmed.ncbi.nlm.nih.gov/19144982
Autor:
Eckhard Thiel, Richard Reinhardt, Mara Molkentin, Nicola Goekbuget, Thomas Burmeister, Hannes Kroenlein, Stefan Schwartz, Dieter Hoelzer
Publikováno v:
Blood. 118:4407-4407
Abstract 4407 Background: Burkitt lymphoma and a subset of diffuse large B-cell lymphomas are characterized by chromosomal alterations affecting the MYC oncogene on 8q24. In most cases MYC is found juxtaposed to the immunoglobulin heavy chain (IGH) g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b22701fa0d518c6554824d89c6ba5c8
https://doi.org/10.1182/blood.v118.21.4407.4407
https://doi.org/10.1182/blood.v118.21.4407.4407
Autor:
Eckhard Thiel, Stefan Schwartz, Daniela Hubert, Mara Molkentin, Claus Meyer, Nicola Goekbuget, Eric Kowarz, Dieter Hoelzer, Rolf Marschalek, Thomas Burmeister
Publikováno v:
Blood. 110:977-977
The pro B and the CD10-negative pre B immunophenotypes are found in approximately 12% and 2–3% of adult acute lymphoblastic leukemia cases, respectively. Both are characterized by a high prevalence of MLL aberrations. MLL fusion genes define a high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55745de115073c4c1eac300e7719c79c
https://doi.org/10.1182/blood.v110.11.977.977
https://doi.org/10.1182/blood.v110.11.977.977