Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Mara K. N. Lawniczak"'
Autor:
Lemonde Bouafou, Boris K. Makanga, Nil Rahola, Marilou Boddé, Marc F. Ngangué, Josquin Daron, Audric Berger, Theo Mouillaud, Alex Makunin, Petra Korlević, Joachim Nwezeobi, Pierre Kengne, Christophe Paupy, Mara K. N. Lawniczak, Diego Ayala
Publikováno v:
Evolutionary Applications, Vol 17, Iss 6, Pp n/a-n/a (2024)
Abstract The adaptation of Anopheles malaria vectors to domestic settings is directly linked to their ability to feed on humans. The strength of this species–habitat association is unequal across the species within the genus, with the major vectors
Externí odkaz:
https://doaj.org/article/6fb7e40434534003a666e84d4c9eeb65
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 2 (2024)
ABSTRACTMicrosporidia are obligate intracellular eukaryotic parasites with an extremely broad host range. They have both economic and public health importance. Ploidy in microsporidia is variable, with a few species formally identified as diploid and
Externí odkaz:
https://doaj.org/article/2c13c6ae39a54d83bd64983007bce650
Autor:
Antoine Dara, Sunil Kumar Dogga, Jesse Rop, Dinkorma Ouologuem, Fatalmoudou Tandina, Arthur M. Talman, Abdoulaye Djimdé, Mara K. N. Lawniczak
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-3 (2022)
Studying malaria transmission biology using scRNA-sequencing provides information on within-host strain diversity and transcriptional states. Here, we comment on our collaborative efforts at establishing single-cell capacities in sub-Saharan Africa a
Externí odkaz:
https://doaj.org/article/971f41067c6945bdb9910574e333674d
Autor:
Martin G. Wagah, Petra Korlević, Christopher Clarkson, Alistair Miles, The Anopheles gambiae 1000 Genomes Consortium, Mara K. N. Lawniczak, Alex Makunin
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-13 (2021)
Abstract Background The emergence of insecticide resistance is a major threat to malaria control programmes in Africa, with many different factors contributing to insecticide resistance in its vectors, Anopheles mosquitoes. CYP6M2 has previously been
Externí odkaz:
https://doaj.org/article/49f2f928b38841c99dc5f67a3a9680a6
Autor:
Eliana Real, Virginia M. Howick, Farah A. Dahalan, Kathrin Witmer, Juliana Cudini, Clare Andradi-Brown, Joshua Blight, Mira S. Davidson, Sunil Kumar Dogga, Adam J. Reid, Jake Baum, Mara K. N. Lawniczak
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Here the authors use single-cell RNA-seq to profile the transmission stages of the human malaria parasite Plasmodium falciparum as it progresses through the Anopheles mosquito. They highlight unique patterns of gene usage throughout this development
Externí odkaz:
https://doaj.org/article/d794f8b7a61a40a4b465c503752b3e54
Autor:
Jeremy K. Herren, Lilian Mbaisi, Enock Mararo, Edward E. Makhulu, Victor A. Mobegi, Hellen Butungi, Maria Vittoria Mancini, Joseph W. Oundo, Evan T. Teal, Silvain Pinaud, Mara K. N. Lawniczak, Jordan Jabara, Godfrey Nattoh, Steven P. Sinkins
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Mircobial symbionts of mosquitoes can affect transmission of human pathogens. Here, Herren et al. identify a microsporidian symbiont in Anopheles gambiae that impairs transmission without affecting mosquito fecundity or survival.
Externí odkaz:
https://doaj.org/article/0fa0d0f941944f2ca631820247f5217a
Autor:
Kathrin Witmer, Farah Aida Dahalan, Tom Metcalf, Arthur M. Talman, Virginia M. Howick, Mara K. N. Lawniczak
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The crossing of the mosquito midgut epithelium by the malaria parasite motile ookinete form represents the most extreme population bottleneck in the parasite life cycle and is a prime target for transmission blocking strategies. However, we have litt
Externí odkaz:
https://doaj.org/article/88890f7ac9334ac889ae2f04375cb72c
Uptake of Plasmodium falciparum Gametocytes During Mosquito Bloodmeal by Direct and Membrane Feeding
Autor:
Arthur M. Talman, Dinkorma T. D. Ouologuem, Katie Love, Virginia M. Howick, Charles Mulamba, Aboubecrin Haidara, Niawanlou Dara, Daman Sylla, Adama Sacko, Mamadou M. Coulibaly, Francois Dao, Cheick P. O. Sangare, Abdoulaye Djimde, Mara K. N. Lawniczak
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Plasmodium falciparum remains one of the leading causes of child mortality, and nearly half of the world’s population is at risk of contracting malaria. While pathogenesis results from replication of asexual forms in human red blood cells, it is th
Externí odkaz:
https://doaj.org/article/5d33fd19840b4845a41408d7fcc6f885
Autor:
Sarah B. Kingan, Haynes Heaton, Juliana Cudini, Christine C. Lambert, Primo Baybayan, Brendan D. Galvin, Richard Durbin, Jonas Korlach, Mara K. N. Lawniczak
Publikováno v:
Genes, Vol 10, Iss 1, p 62 (2019)
A high-quality reference genome is a fundamental resource for functional genetics, comparative genomics, and population genomics, and is increasingly important for conservation biology. PacBio Single Molecule, Real-Time (SMRT) sequencing generates lo
Externí odkaz:
https://doaj.org/article/33403a4f21c543deaf48f18c8a77c210
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010346 (2022)
Early diverging lineages such as trypanosomes can provide clues to the evolution of sexual reproduction in eukaryotes. In Trypanosoma brucei, the pathogen that causes Human African Trypanosomiasis, sexual reproduction occurs in the salivary glands of
Externí odkaz:
https://doaj.org/article/05b3fd978cb540eda1ae2920ea88448c