Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mara J. Kröner"'
Autor:
Eva van Ingen, Amanda C. Foks, Mara J. Kröner, Johan Kuiper, Paul H.A. Quax, Ilze Bot, Anne Yaël Nossent
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 638-649 (2019)
We have previously shown that third-generation antisense (3GA) inhibition of 14q32 microRNA (miRNA)-494 reduced early development of atherosclerosis. However, patients at risk of atherosclerotic complications generally present with advanced and unsta
Externí odkaz:
https://doaj.org/article/c0ecfbcecf4a4e57b8835ececd858d65
Autor:
Ilze Bot, Natalia V. Ortiz Zacarías, Wilhelmus E. A. de Witte, Henk de Vries, Peter J. van Santbrink, Daniël van der Velden, Mara J. Kröner, Dirk-Jan van der Berg, Dean Stamos, Elizabeth C. M. de Lange, Johan Kuiper, Adriaan P. IJzerman, Laura H. Heitman
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract CC Chemokine Receptor 2 (CCR2) and its endogenous ligand CCL2 are involved in a number of diseases, including atherosclerosis. Several CCR2 antagonists have been developed as potential therapeutic agents, however their in vivo clinical effic
Externí odkaz:
https://doaj.org/article/be41579bc6074a96b13bbf8097e120c1
Autor:
Jacob Amersfoort, Hidde Douna, Frank H. Schaftenaar, Amanda C. Foks, Mara J. Kröner, Peter J. van Santbrink, Gijs H. M. van Puijvelde, Ilze Bot, Johan Kuiper
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Macroautophagy (or autophagy) is a conserved cellular process in which cytoplasmic cargo is targeted for lysosomal degradation. Autophagy is crucial for the functional integrity of different subsets of T cells in various developmental stages. Since a
Externí odkaz:
https://doaj.org/article/8cd87af9006544a1af0eb617c945cff4
Autor:
Ilze Bot, Daniël van der Velden, Merel Bouwman, Mara J. Kröner, Johan Kuiper, Paul H. A. Quax, Margreet R. de Vries
Publikováno v:
Cells, Vol 9, Iss 3, p 701 (2020)
Mast cells have been associated with arteriogenesis and collateral formation. In advanced human atherosclerotic plaques, mast cells have been shown to colocalize with plaque neovessels, and mast cells have also been associated with tumor vascularizat
Externí odkaz:
https://doaj.org/article/177fd1e983264fb9aaed7e62045acf15
Autor:
Paul H.A. Quax, Merel Bouwman, Daniël van der Velden, Ilze Bot, Margreet R. de Vries, Johan Kuiper, Mara J. Kröner
Publikováno v:
Cells
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 701 (2020)
Cells, 9(3), 701
Cells, 9(3). MDPI
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 701 (2020)
Cells, 9(3), 701
Cells, 9(3). MDPI
Mast cells have been associated with arteriogenesis and collateral formation. In advancedhuman atherosclerotic plaques, mast cells have been shown to colocalize with plaque neovessels,and mast cells have also been associated with tumor vascularizatio
Autor:
Hidde Douna, Jacob Amersfoort, Gijs H.M. van Puijvelde, Ilze Bot, Jan W. Drijfhout, Johan Kuiper, Mara J. Kröner, Amanda C. Foks, Frank H. Schaftenaar, Bram Slütter
Publikováno v:
Scientific Reports, 9(1), 17391
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Cardiovascular diseases form the most common cause of death worldwide, with atherosclerosis as main etiology. Atherosclerosis is marked by cholesterol rich lipoprotein deposition in the artery wall, evoking a pathogenic immune response. Characteristi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f8e07924453ef9dd1a6ebe465a0795
http://hdl.handle.net/1887/82160
http://hdl.handle.net/1887/82160
Inhibition of miR-494 reduces early carotid artery atherosclerosis. However, patients generally present with advanced atherosclerosis. Therefore, we investigated the effect of miR-494 inhibition on advanced atherosclerotic plaques.LDLr-/- mice were p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ebe152522f61641ce85a97177652084
http://hdl.handle.net/1887/3198973
http://hdl.handle.net/1887/3198973
Autor:
Mara J. Kröner, A. Wezel, Hidde Douna, Marie A.C. Depuydt, M.N.A. Bernabé Kleijn, Hideo Yagita, G.H.M. van Puijvelde, M.B. Kiss, Amanda C. Foks, Jacob Amersfoort, Harm Smeets, Johan Kuiper, Frank H. Schaftenaar, Bram Slütter, Christoph J. Binder, Ilze Bot
Publikováno v:
Cardiovascular Research, 116(2), 295-305
Cardiovascular Research
Cardiovascular Research
The immune system is strongly involved in atherosclerosis and immune regulation generally leads to attenuated atherosclerosis. B- and T-lymphocyte attenuator (BTLA) is a novel co-receptor that negatively regulates the activation of B and T cells; how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1f721475fcb96b14f1883a750dbff0
https://hdl.handle.net/1887/79796
https://hdl.handle.net/1887/79796
Autor:
Laura M. de Jong, Lidewij R. de Leeuw, Mara J. Kröner, Joya E. Nahon, Menno Hoekstra, Miranda Van Eck
Publikováno v:
Biochimica et Biophysica Acta: Molecular Basis of Disease, 1865(6), 1402-1409
The nuclear receptor liver X receptor (LXR) impacts on cholesterol metabolism as well as hepatic lipogenesis via transcriptional regulation. It is proposed that inhibition of the protein arginine methyltransferase 3 (PRMT3) uncouples these two transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe7c2c65e52698e12e2b6eb36f8cb97
https://hdl.handle.net/1887/85615
https://hdl.handle.net/1887/85615
Autor:
Frank H. Schaftenaar, Hidde Douna, Gijs H.M. van Puijvelde, Jacob Amersfoort, Ilze Bot, Peter J. van Santbrink, Amanda C. Foks, Johan Kuiper, Mara J. Kröner
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, 9, 2937
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, 9, 2937
Frontiers in Immunology, Vol 9 (2018)
Macroautophagy (or autophagy) is a conserved cellular process in which cytoplasmic cargo is targeted for lysosomal degradation. Autophagy is crucial for the functional integrity of different subsets of T cells in various developmental stages. Since a