Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Mara Fiorani"'
Autor:
Giulia Blandino, Mara Fiorani, Barbara Canonico, Rita De Matteis, Andrea Guidarelli, Mariele Montanari, Gloria Buffi, Lucia Coppo, Elias S.J. Arnér, Orazio Cantoni
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102915- (2023)
Long-term treatment of schizophrenia with clozapine (CLZ), an atypical antipsychotic drug, is associated with an increased incidence of metabolic disorders mediated by poorly understood mechanisms. We herein report that CLZ, while slowing down the mo
Externí odkaz:
https://doaj.org/article/d1328900c1f641a38923911fd7ee06ff
Publikováno v:
Redox Biology, Vol 20, Iss , Pp 285-295 (2019)
A low concentration of arsenite (6 h), selectively stimulating the intraluminal crosstalk between the inositol-1, 4, 5-triphosphate receptor and the ryanodine receptor (RyR), increased the mitochondrial transport of RyR-derived Ca2+ through the mitoc
Externí odkaz:
https://doaj.org/article/755dd5c855c3407183dd212de48682b9
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 1034 (2022)
Long-term ingestion of arsenicals, a heterogeneous group of toxic compounds, has been associated with a wide spectrum of human pathologies, which include various malignancies. Although their mechanism of toxicity remains largely unknown, it is genera
Externí odkaz:
https://doaj.org/article/aca2294d81f94f66a42ea8bd8729a6b8
Autor:
Federica Sola, Mariele Montanari, Mara Fiorani, Chiara Barattini, Caterina Ciacci, Sabrina Burattini, Daniele Lopez, Alfredo Ventola, Loris Zamai, Claudio Ortolani, Stefano Papa, Barbara Canonico
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 3069 (2022)
Fluorescent silica nanoparticles (SiNPs) appear to be a promising imaging platform, showing a specific subcellular localization. In the present study, we first investigated their preferential mitochondrial targeting in myeloid cells, by flow cytometr
Externí odkaz:
https://doaj.org/article/7b049f56aea549e3ab1eb2b482231756
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
We investigated the effects of prostaglandin E2 (PGE2), an important inflammatory lipid mediator, on the cytotoxicity–genotoxicity induced by arsenite. With the use of a toxicity paradigm in which the metalloid uniquely induces mitochondrial supero
Externí odkaz:
https://doaj.org/article/3abb38110a804dc69910007536b66b36
Publikováno v:
International Journal of Radiation Biology. 97:1055-1062
Mitochondria represent critical sites for reactive oxygen species (ROS) production, which dependent on concentration is responsible for the regulation of both physiological and pathological processes.Antioxidants in mitochondria regulate the redox ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3116543640f6d758e5f086bb61b240e4
https://doi.org/10.1080/09553002.2020.1721604
https://doi.org/10.1080/09553002.2020.1721604
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 373:62-71
The present study used human myeloid leukemia U937 cells, a versatile promonocytic cellular system that, based on its endoplasmic reticulum (ER)/mitochondria functional relationships, responds to low micromolar concentrations of arsenite with a singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b43c264920fe1878eb3071b3c538a5d
https://doi.org/10.1124/jpet.119.262469
https://doi.org/10.1124/jpet.119.262469
Our recent studies suggest that arsenite stimulates the crosstalk between the inositol 1, 4, 5-triphosphate receptor (IP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3d005f3d7e19837f35e3b86e21f7b7
https://hdl.handle.net/11576/2703430
https://hdl.handle.net/11576/2703430
Autor:
Andrea Spina, Andrea Guidarelli, Mara Fiorani, Ersilia Varone, Alessia Catalani, Ester Zito, Orazio Cantoni
Publikováno v:
Biochemical pharmacology. 198
Arsenite, a well-established human carcinogen and toxic compound, promotes the formation of mitochondrial superoxide (mitoO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6690720f93b148c4b82c00d0feafa62e
https://pubmed.ncbi.nlm.nih.gov/35189109
https://pubmed.ncbi.nlm.nih.gov/35189109