Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mara Del Vecchio"'
Autor:
Stephanie Vrijsen, Céline Vrancx, Mara Del Vecchio, Johannes V. Swinnen, Patrizia Agostinis, Joris Winderickx, Peter Vangheluwe, Wim Annaert
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Neurodegenerative diseases (NDs) are generally considered proteinopathies but whereas this may initiate disease in familial cases, onset in sporadic diseases may originate from a gradually disrupted organellar homeostasis. Herein, endolysosomal abnor
Externí odkaz:
https://doaj.org/article/71b18339eb854ed494b75e0a5a5c3764
Autor:
Geert Callewaert, Petra D’hooge, Tien-Yang Ma, Mara Del Vecchio, Vincent Van Eyck, Vanessa Franssens, Joris Winderickx
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The yeast Saccharomyces cerevisiae is a powerful model to study the molecular mechanisms underlying α-synuclein (α-syn) cytotoxicity. This is due to the high degree of conservation of cellular processes with higher eukaryotes and the fact that yeas
Externí odkaz:
https://doaj.org/article/ba0d6b1586cd4b95b0bba4a6db6e416b
Autor:
Valentina Vapore, Corrado Mazzaglia, Diego Sibilia, Mara Del Vecchio, Gernot Fruhmann, Marta Valenti, Elena Miranda, Teresa Rinaldi, Joris Winderickx, Cristina Mazzoni
Publikováno v:
Microorganisms, Vol 9, Iss 7, p 1498 (2021)
FENIB (familial encephalopathy with neuroserpin inclusion bodies) is a human monogenic disease caused by point mutations in the SERPINI1 gene, characterized by the intracellular deposition of polymers of neuroserpin (NS), which leads to proteotoxicit
Externí odkaz:
https://doaj.org/article/7726b019a1154a09aed2e73f897d20c7
Autor:
Mara Del Vecchio, Lucia Amado, Alexandra P. Cogan, Els Meert, Joelle Rosseels, Vanessa Franssens, Sander K. Govers, Joris Winderickx, Ayelén González Montoro
Publikováno v:
Molecular Biology of the Cell.
The protein alpha-synuclein (α-syn) is one of the major factors linked to Parkinson's disease, yet how its misfolding and deposition contribute to the pathology remains largely elusive. Recently, contact sites among organelles were implicated in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::889ce390b2db2187dab37ff8cdef8d4e
https://doi.org/10.1091/mbc.e23-01-0029
https://doi.org/10.1091/mbc.e23-01-0029
Autor:
Teresa Rinaldi, Joris Winderickx, Diego Sibilia, Elena Miranda, Corrado Mazzaglia, Cristina Mazzoni, Mara Del Vecchio, Marta Valenti, Gernot Fruhmann, Valentina Vapore
Publikováno v:
Microorganisms
Microorganisms, Vol 9, Iss 1498, p 1498 (2021)
Volume 9
Issue 7
Microorganisms, Vol 9, Iss 1498, p 1498 (2021)
Volume 9
Issue 7
FENIB (familial encephalopathy with neuroserpin inclusion bodies) is a human monogenic disease caused by point mutations in the SERPINI1 gene, characterized by the intracellular deposition of polymers of neuroserpin (NS), which leads to proteotoxicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56e6822c9c74df19ded510746788762
https://doi.org/10.3390/microorganisms9071498
https://doi.org/10.3390/microorganisms9071498
Autor:
Geert, Callewaert, Petra, D'hooge, Tien-Yang, Ma, Mara, Del Vecchio, Vincent, Van Eyck, Vanessa, Franssens, Joris, Winderickx
Publikováno v:
Frontiers in Genetics
The yeast Saccharomyces cerevisiae is a powerful model to study the molecular mechanisms underlying α-synuclein (α-syn) cytotoxicity. This is due to the high degree of conservation of cellular processes with higher eukaryotes and the fact that yeas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa456bd9bf68c0e2becf38df8b58199d
https://pubmed.ncbi.nlm.nih.gov/32457789
https://pubmed.ncbi.nlm.nih.gov/32457789
Autor:
Daniel P. Mulvihill, Melody Cools, Jimmy Beckers, Joke Verelst, David Seynnaeve, Joris Winderickx, Gernot Fruhmann, Mara Del Vecchio, Vanessa Franssens
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1947 (2018)
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1947 (2018)
In this review article, yeast model-based research advances regarding the role of Amyloid-β (Aβ), Tau and frameshift Ubiquitin UBB+1 in Alzheimer’s disease (AD) are discussed. Despite having limitations with regard to intercellular and cognitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3811351782fb9948d5373914f9f7f7c
https://doi.org/10.3390/ijms19071947
https://doi.org/10.3390/ijms19071947