Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mara Cruellas"'
Autor:
Natalia Alonso, Sebastián Menao, Rodrigo Lastra, María Arruebo, María P. Bueso, Esther Pérez, M. Laura Murillo, María Álvarez, Alba Alonso, Soraya Rebollar, Mara Cruellas, Dolores Arribas, Mónica Ramos, Dolores Isla, Juan José Galano-Frutos, Helena García-Cebollada, Javier Sancho, Raquel Andrés
Publikováno v:
Frontiers in Genetics, Vol 14 (2024)
Inherited mutations in the CHEK2 gene have been associated with an increased lifetime risk of developing breast cancer (BC). We aim to identify in the study population the prevalence of mutations in the CHEK2 gene in diagnosed BC patients, evaluate t
Externí odkaz:
https://doaj.org/article/67daac7da8254e2b8514a30cfcc2a9ef
Autor:
Diego Gomez-Puerto, Alba Llop-Guevara, Mara Cruellas, Sara Torres-Esquius, Javier De La Torre, Vicente Peg, Judith Balmaña, Isabel Pimentel
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Triple-negative breast cancer is the most aggressive subtype of mammary carcinoma. In the early stage, neoadjuvant chemotherapy (NAC) is the standard of care for prognostic stratification and the best adjuvant treatment strategy. A 30-year-old female
Externí odkaz:
https://doaj.org/article/86ee02c4d02343bdb39ba72c58ddab49
Autor:
Maitane Ocáriz-Díez, Mara Cruellas, Marta Gascón, Rodrigo Lastra, Luis Martínez-Lostao, Ariel Ramírez-Labrada, José Ramón Paño, Andrea Sesma, Irene Torres, Alfonso Yubero, Julián Pardo, Dolores Isla, Eva M. Gálvez
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The advances in molecular biology and the emergence of Next Generation Sequencing (NGS) have revealed that microbiome composition is closely related with health and disease, including cancer. This relationship affects different levels of cancer such
Externí odkaz:
https://doaj.org/article/3d61d072998e42e181eabeaf87b0c7ff
Autor:
Marta Gascón, Dolores Isla, Mara Cruellas, Eva M. Gálvez, Rodrigo Lastra, Maitane Ocáriz, José Ramón Paño, Ariel Ramírez, Andrea Sesma, Irene Torres-Ramón, Alfonso Yubero, Julián Pardo, Luis Martínez-Lostao
Publikováno v:
Cells, Vol 9, Iss 6, p 1525 (2020)
The molecular and cell determinants that modulate immune checkpoint (ICI) efficacy in lung cancer are still not well understood. However, there is a necessity to select those patients that will most benefit from these new treatments. Recent studies s
Externí odkaz:
https://doaj.org/article/c185481f819c47e49b8a770ab89cbf7a
Autor:
David Humberto Marmolejo Castañeda, Mara Cruellas Lapeña, Estela Carrasco López, Gloria Aparicio Español, Claudia Valverde Morales, Adrià López-Fernández, Eduard Pérez Ballesteros, Sara Torres-Esquius, Mónica Pardo Muñoz, Judith Balmaña Gelpi
Publikováno v:
Familial Cancer. 22:99-102
Rothmund-Thomson syndrome, a heterogeneous genodermatosis with autosomal recessive hereditary pattern, is an uncommon cancer susceptibility genetic syndrome. To date, only 400 cases have been reported in the literature, and the severity of the featur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da9272d435451412bc371657900820d
https://doi.org/10.1007/s10689-022-00303-2
https://doi.org/10.1007/s10689-022-00303-2
Autor:
Elshad, Hasanov, Isabel, Pimentel, Mara, Cruellas, Mark A, Lewis, Eric, Jonasch, Judith, Balmaña
Publikováno v:
American Society of Clinical Oncology Educational Book. :808-824
Advances in the genetic basis of different tumors have led to identification of tumor vulnerabilities that can be turn into targeted therapies. In this regard, PARP inhibitors cause synthetic lethality with tumors harboring BRCA1 or BRCA2 genetic alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75430d57d0bb7698ef1336aad258f47e
https://doi.org/10.1200/edbk_350232
https://doi.org/10.1200/edbk_350232
Autor:
Diego Casas Deza, María Zapata García, Natalia Alonso Martín, Raquel Andrés Conejero, Andrea Sesma Goñi, Miguel Lafuente Blasco, Marta Gascón Ruiz, Mara Cruellas Lapeña, Elisa Quílez Bielsa, Laura Murillo Jaso, Maria Zurera Berjaga, Maitane Ocariz Diez
Publikováno v:
Revista de Senología y Patología Mamaria. 34:93-99
Objective Clinical trials have shown that Nab-paclitaxel is more effective than paclitaxel in the treatment of metastatic breast cancer (MBC). Although the incidence of cancer increases with age, elderly patients are under-represented in clinical tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43021f1716782bab260333ee1db7f19e
https://doi.org/10.1016/j.senol.2020.06.006
https://doi.org/10.1016/j.senol.2020.06.006
Autor:
Eva Blondeaux, Luca Arecco, Kevin Punie, Rossella Graffeo, Angela Toss, Carmine De Angelis, Lucia Trevisan, Giulia Buzzatti, Sabine C. Linn, Peter Dubsky, Mara Cruellas, Ann H. Partridge, Judith Balmaña, Shani Paluch-Shimon, Matteo Lambertini
Publikováno v:
Scientia
Breast cancer; Prognosis; Treatment Cáncer de mama; Pronóstico; Tratamiento Càncer de mama; Pronòstic; Tractament Approximately 10% of breast cancers are associated with the inheritance of a pathogenic variant (PV) in one of the breast cancer sus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6ec0c101b9aebc9e5ef118a72b2f7d
https://doi.org/10.1016/j.ctrv.2023.102522
https://doi.org/10.1016/j.ctrv.2023.102522
Autor:
Andri Papakonstantinou, Alberto Gonzalez-Medina, Judit Matito, Marta Ligero, Fiorella Ruiz-Pace, Anna Suñol, Joaquin Rivero, Roberta Fasani, Mara Cruellas, Vicente Peg, Maria Borrell, Isabel Pimentel, Santiago Escriva De Romani Munoz, Judith Balmana Gelpi, Paolo Nuciforo, Rodrigo Dienstmann, Cristina Saura, Raquel Perez-Lopez, Mafalda Oliveira, Ana Vivancos
Publikováno v:
Journal of Clinical Oncology. 40:1086-1086
1086 Background: Genomic alterations driving MBC progression may be better captured by ctDNA reflecting clonal evolution, but it is currently unknow whether ctDNA analysis can replace tumor sequencing for clinical decision purposes. Aim: to study the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5df522c04db0cacdfe02e7125175999
https://doi.org/10.1200/jco.2022.40.16_suppl.1086
https://doi.org/10.1200/jco.2022.40.16_suppl.1086
Autor:
Jose Ramón Paño Pardo, Maria Zurera Berjaga, Natalia Alonso Marin, Alba Moratiel Pellitero, Maitane Ocariz Diez, Rodrigo Lastra del Prado, Marta Gascón Ruiz, Ines Ruiz Moreno, Mara Cruellas, María Álvarez Alejandro, María Zapata García
Publikováno v:
Medicina Paliativa.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6b7f8604a7839aded99f37325e94195
https://doi.org/10.20986/medpal.2021.1265/2021
https://doi.org/10.20986/medpal.2021.1265/2021