Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mara Carreño"'
Autor:
Heidi M. Schmidt, Evan R. DeVallance, Sara E. Lewis, Katherine C. Wood, Gowtham K. Annarapu, Mara Carreño, Scott A. Hahn, Madison Seman, Brooke A. Maxwell, Emily A. Hileman, Julia Z. Xu, Murugesan Velayutham, Werner J. Geldenhuys, Dario A. Vitturi, Sruti Shiva, Eric E. Kelley, Adam C. Straub
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102636- (2023)
Xanthine oxidase (XO) catalyzes the catabolism of hypoxanthine to xanthine and xanthine to uric acid, generating oxidants as a byproduct. Importantly, XO activity is elevated in numerous hemolytic conditions including sickle cell disease (SCD); howev
Externí odkaz:
https://doaj.org/article/fc1d13f5ed7a4f76bf1f12017427f9c4
Autor:
Jimena Hochmann, Felipe Parietti, Jennyfer Martínez, Ana C Lopez, Mara Carreño, Celia Quijano, Enrique Boccardo, Laura Sichero, Matías N Möller, Santiago Mirazo, Juan Arbiza
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 115 (2020)
BACKGROUND High-risk human papillomaviruses (HR-HPVs) are the etiological agents of cervical cancer. Among them, types 16 and 18 are the most prevalent worldwide. The HPV genome encodes three oncoproteins (E5, E6, and E7) that possess a high transfor
Externí odkaz:
https://doaj.org/article/b57eb53f45b845579091e0a815479b9b
Autor:
Mara Carreño, Maria F. Pires, Steven R. Woodcock, Tomasz Brzoska, Samit Ghosh, Sonia R. Salvatore, Fei Chang, Nicholas K. H. Khoo, Matthew Dunn, Nora Connors, Shuai Yuan, Adam C. Straub, Stacy G. Wendell, Gregory J. Kato, Bruce A. Freeman, Solomon F. Ofori-Acquah, Prithu Sundd, Francisco J. Schopfer, Dario A. Vitturi
Publikováno v:
Science advances. 8(26)
The up-regulation of kynurenine metabolism induces immunomodulatory responses via incompletely understood mechanisms. We report that increases in cellular and systemic kynurenine levels yield the electrophilic derivative kynurenine-carboxyketoalkene
Publikováno v:
Free Radical Biology and Medicine. 192:139
Autor:
Heidi Schmidt, Scott Hahn, Gowtham Annarapu, Mara Carreño, Katherine Wood, Sruti Shiva, Dario Vitturi, Eric Kelley, Adam Straub
Publikováno v:
Free Radical Biology and Medicine. 180:s53
Autor:
Solomon F. Ofori-Acquah, Maria F. Pires, Francisco J. Schopfer, Mara Carreño, Bruce A. Freeman, Steven R. Woodcock, Gregory J. Kato, Samit Ghosh, Sonia R. Salvatore, Dario A. Vitturi
Publikováno v:
Free Radical Biology and Medicine. 159:S35-S36
Autor:
Santiago Mirazo, Jennyfer Martínez, Juan Arbiza, Matías N. Möller, Celia Quijano, Laura Sichero, Enrique Boccardo, Jimena Hochmann, Mara Carreño, Felipe Parietti, Ana C Lopez
Publikováno v:
Memórias do Instituto Oswaldo Cruz
Memórias do Instituto Oswaldo Cruz, Volume: 115, Article number: e190405, Published: 16 MAR 2020
Memórias do Instituto Oswaldo Cruz., Vol 115 (2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
COLIBRI
Universidad de la República
instacron:Universidad de la República
Memórias do Instituto Oswaldo Cruz, Volume: 115, Article number: e190405, Published: 16 MAR 2020
Memórias do Instituto Oswaldo Cruz., Vol 115 (2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
COLIBRI
Universidad de la República
instacron:Universidad de la República
BACKGROUND High-risk human papillomaviruses (HR-HPVs) are the etiological agents of cervical cancer. Among them, types 16 and 18 are the most prevalent worldwide. The HPV genome encodes three oncoproteins (E5, E6, and E7) that possess a high transfor
Autor:
Santiago Mirazo, Jennyfer Martínez, Matías N. Möller, JP Hochmann Valls, Laura Sichero, Celia Quijano, Ana C Lopez, F Parietti, Juan Arbiza, Mara Carreño
Publikováno v:
E-Poster viewings.
Objectives The main aim of this work is to study how E5, E6 and E7 oncogenes of human papillomaviruses type 18 could cooperate among each other to boost key cancer cell features such as uncontrolled cell proliferation, enhanced migration capacity, in
Autor:
Adam C. Straub, Gowtham K Annarapu, Francisco J. Schopfer, Eric E. Kelley, Dario A. Vitturi, Mara Carreño, Heidi M Schmidt, Sruti Shiva, Scott Hahn
Publikováno v:
Blood. 136:12-12
Xanthine oxidase (XO) is a key enzyme in the purine degradation pathway, catalyzing the catabolism of hypoxanthine to xanthine and xanthine to uric acid. A byproduct of these reactions is the generation of the reactive oxygen species (ROS), hydrogen
Autor:
Leonardo Santos, Ana Denicola, Carlos Batthyány, Mariana Bresque, Carlos Escande, Mara Carreño
Publikováno v:
Free Radical Biology and Medicine. 112:41-42
Sirtuins are NAD+-dependent deacetylases reported as key factors in metabolism regulation, inflammation and stress response. Human sirtuin 6 (hSIRT6) is known as a histone 3 deacetylase despite of its low activity in vitro. Its deacetylase activity i