Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mara C. Inniss"'
Autor:
Alexander D. Naydich, Shannon N. Nangle, Johannes J. Bues, Disha Trivedi, Nabeel Nissar, Mara C. Inniss, Matthew J. Niederhuber, Jeffrey C. Way, Pamela A. Silver, David T. Riglar
Publikováno v:
mSystems, Vol 4, Iss 4 (2019)
ABSTRACT Engineering synthetic circuits into intestinal bacteria to sense, record, and respond to in vivo signals is a promising new approach for the diagnosis, treatment, and prevention of disease. However, because the design of disease-responsive c
Externí odkaz:
https://doaj.org/article/a670a59b6f6541ef8395330c64f5fd82
Autor:
Barbara Jusiak, Liliana Wroblewska, Timothy K. Lu, Mara C. Inniss, Ron Weiss, Lin Zhang, Kalpanie Bandara
Publikováno v:
Biotechnology and Bioengineering. 114:1837-1846
As CHO cell line development for biotherapeutic production becomes more sophisticated through the availability of the CHO genome sequence, the ability to accurately and reproducibly engineer the host cell genome has become increasingly important. Mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5864f6b9dcad2d345f9908283521924
https://doi.org/10.1002/bit.26268
https://doi.org/10.1002/bit.26268
Autor:
Matthew J Neiderhuber, Disha Trivedi, Johannes J. Bues, Alexander Naydich, Shannon N. Nangle, Jeffrey C. Way, Nabeel Nissar, David T. Riglar, Mara C. Inniss, Pamela A. Silver
Publikováno v:
mSystems, Vol 4, Iss 4 (2019)
mSystems
mSystems
The gut is a largely obscure and inaccessible environment. The use of live, engineered probiotics to detect and respond to disease signals in vivo represents a new frontier in the management of gut diseases. Engineered probiotics have also shown prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d67c3cebf9536f8f99024caa009836e
https://doi.org/10.1128/msystems.00125-19
https://doi.org/10.1128/msystems.00125-19
Autor:
Jeffrey C. Way, Mara C. Inniss, Disha Trivedi, Shannon N. Nangle, Matthew J Neiderhuber, Nabeel Nissar, Pamela A. Silver, Alexander Naydich, David T. Riglar, Johannes J. Bues
The composition and function of the gut microbiota are strongly associated with human health, and dysbiosis is linked to an array of diseases, ranging from obesity and diabetes to infection and inflammation. Engineering synthetic circuits into gut ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f0f20e4f3baceb72f414c2b0b44bd3
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0167162 (2016)
PLoS ONE, Vol 11, Iss 12, p e0167162 (2016)
A robust cellular counter could enable synthetic biologists to design complex circuits with diverse behaviors. The existing synthetic-biological counters, responsive to the beginning of the pulse, are sensitive to the pulse duration. Here we present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150eecf82556c94a05a927df9c80c14f
http://europepmc.org/articles/PMC5131961
http://europepmc.org/articles/PMC5131961
Autor:
Mara C, Inniss, Kalpanie, Bandara, Barbara, Jusiak, Timothy K, Lu, Ron, Weiss, Liliana, Wroblewska, Lin, Zhang
Publikováno v:
Biotechnology and bioengineering. 114(8)
As CHO cell line development for biotherapeutic production becomes more sophisticated through the availability of the CHO genome sequence, the ability to accurately and reproducibly engineer the host cell genome has become increasingly important. Mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a24bc3d61d0b6431838b9aaded971449
https://pubmed.ncbi.nlm.nih.gov/28186334
https://pubmed.ncbi.nlm.nih.gov/28186334
Publikováno v:
Genes & Development. 26:1486-1497
A variety of biological phenomena, from disease progression to stem cell differentiation, are typified by a prolonged cellular response to a transient environmental cue. While biologically relevant, heterogeneity in these long-term responses is diffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d2bd46131f6f30951ad748b657dcd8
https://doi.org/10.1101/gad.189035.112
https://doi.org/10.1101/gad.189035.112
Autor:
Mark Moffat, Robert J. Young, James Rance, Wendy L. Cox, Shu Han, Mara C. Inniss, Heather Jones, Lin Zhang, Baohong Zhang
Publikováno v:
Biotechnology progress. 31(6)
To meet product quality and cost parameters for therapeutic monoclonal antibody (mAb) production, cell lines are required to have excellent growth, stability, and productivity characteristics. In particular, cell line generation stability is critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ef0166f1afc4b08afd3621777c19aa
https://pubmed.ncbi.nlm.nih.gov/26399954
https://pubmed.ncbi.nlm.nih.gov/26399954
Autor:
Pamela A. Silver, Mara C. Inniss
Publikováno v:
Current biology : CB. 23(17)
Cellular memory — conversion of a transient signal into a sustained response — is a common feature of biological systems. Synthetic biologists aim to understand and re-engineer such systems in a reliable and predictable manner. Synthetic memory c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8b51e9be6ee019b8e8c522a55f32eb
https://pubmed.ncbi.nlm.nih.gov/24028965
https://pubmed.ncbi.nlm.nih.gov/24028965
Autor:
Alain Viel, Morgan L Paull, Pamela A. Silver, Anugraha M. Raman, Mara C. Inniss, Patrick M. Boyle, Michael A Gedeon, Karmella A. Haynes, Jonathan G dewerd, Oliver Medvedik, Aaron Deardon, Christina M. Agapakis, Jacqueline Y Quinn, Tamara Jane Brenner, Kurt Schellenberg, Julia C. Winn, Mark R. Theilmann, Jagesh V. Shah, George M. Church, Devin R. Burrill, Lu Wang
Publikováno v:
Journal of Biological Engineering, Vol 6, Iss 1, p 8 (2012)
Journal of Biological Engineering
Boyle, Patrick M; Burrill, Devin R; Inniss, Mara C; Agapakis, Christina M; Deardon, Aaron; DeWerd, Jonathan G; et al.(2012). A BioBrick compatible strategy for genetic modification of plants. Journal of Biological Engineering, 6(1), 8. doi: http://dx.doi.org/10.1186/1754-1611-6-8. Retrieved from: http://www.escholarship.org/uc/item/2n01v0mv
Journal of Biological Engineering
Boyle, Patrick M; Burrill, Devin R; Inniss, Mara C; Agapakis, Christina M; Deardon, Aaron; DeWerd, Jonathan G; et al.(2012). A BioBrick compatible strategy for genetic modification of plants. Journal of Biological Engineering, 6(1), 8. doi: http://dx.doi.org/10.1186/1754-1611-6-8. Retrieved from: http://www.escholarship.org/uc/item/2n01v0mv
Background Plant biotechnology can be leveraged to produce food, fuel, medicine, and materials. Standardized methods advocated by the synthetic biology community can accelerate the plant design cycle, ultimately making plant engineering more widely a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7aab765f93622e92b543789e9e15937
http://www.jbioleng.org/content/6/1/8
http://www.jbioleng.org/content/6/1/8