Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Mara, Monetti"'
Autor:
Rachel J. Roth Flach, Eliza Bollinger, Allan R. Reyes, Brigitte Laforest, Bethany L. Kormos, Shenping Liu, Matthew R. Reese, Luis A. Martinez Alsina, Leanne Buzon, Yuan Zhang, Bruce Bechle, Amy Rosado, Parag V. Sahasrabudhe, John Knafels, Samit K. Bhattacharya, Kiyoyuki Omoto, John C. Stansfield, Liam D. Hurley, LouJin Song, Lina Luo, Susanne B. Breitkopf, Mara Monetti, Teresa Cunio, Brendan Tierney, Frank J. Geoly, Jake Delmore, C. Parker Siddall, Liang Xue, Ka N. Yip, Amit S. Kalgutkar, Russell A. Miller, Bei B. Zhang, Kevin J. Filipski
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Branched chain amino acid (BCAA) catabolic impairments have been implicated in several diseases. Branched chain ketoacid dehydrogenase (BCKDH) controls the rate limiting step in BCAA degradation, the activity of which is inhibited by BCKDH k
Externí odkaz:
https://doaj.org/article/f9d9823491ce46a3808353f3a122b4ab
Autor:
Stephen E. Flaherty, Olivier Bezy, Wei Zheng, Dong Yan, Xiangping Li, Srinath Jagarlapudi, Bina Albuquerque, Ryan M. Esquejo, Matthew Peloquin, Meriem Semache, Arturo Mancini, Liya Kang, Doreen Drujan, Susanne B. Breitkopf, John D. Griffin, Pierre M. Jean Beltran, Liang Xue, John Stansfield, Evanthia Pashos, Quazi Shakey, Christian Pehmøller, Mara Monetti, Morris J. Birnbaum, Jean-Philippe Fortin, Zhidan Wu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Urocortin 2 (UCN2) acts as a ligand for the G protein-coupled receptor corticotropin-releasing hormone receptor 2 (CRHR2). UCN2 has been reported to improve or worsen insulin sensitivity and glucose tolerance in vivo. Here we show that acute
Externí odkaz:
https://doaj.org/article/c30f771320644d0bb5638ece93bbd9e2
Autor:
Christopher M. Brennan, Abby S. Hill, Michael St. Andre, Xianfeng Li, Vijaya Madeti, Susanne Breitkopf, Seth Garren, Liang Xue, Tamara Gilbert, Angela Hadjipanayis, Mara Monetti, Charles P. Emerson, Robert Moccia, Jane Owens, Nicolas Christoforou
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 11 (2022)
Externí odkaz:
https://doaj.org/article/1bbf0c3ccd564919803d206fc16f77d4
Autor:
Ryan M. Esquejo, Christopher T. Salatto, Jake Delmore, Bina Albuquerque, Allan Reyes, Yuji Shi, Rob Moccia, Emily Cokorinos, Matthew Peloquin, Mara Monetti, Jason Barricklow, Eliza Bollinger, Brennan K. Smith, Emily A. Day, Chuong Nguyen, Kieran F. Geoghegan, John M. Kreeger, Alan Opsahl, Jessica Ward, Amit S. Kalgutkar, David Tess, Lynne Butler, Norimitsu Shirai, Timothy F. Osborne, Gregory R. Steinberg, Morris J. Birnbaum, Kimberly O. Cameron, Russell A. Miller
Publikováno v:
EBioMedicine, Vol 31, Iss , Pp 122-132 (2018)
Dysregulation of hepatic lipid and cholesterol metabolism is a significant contributor to cardiometabolic health, resulting in excessive liver lipid accumulation and ultimately non-alcoholic steatohepatitis (NASH). Therapeutic activators of the AMP-A
Externí odkaz:
https://doaj.org/article/3a6b1a8ecd964eee8550aafb2b27ef05
Autor:
Zhidan Wu, Stephen Flaherty, Olivier Bezy, Wei Zheng, Dong Yan, Xiangping Li, Srinath Jagarlapudi, Bina Albuquerque, Ryan Esq, Matt Peloquin, Meriem Semache, Arturo Mancini, Liya Kang, Doreen Drujan, Susanne Breitkopf, Evanthia Pashos, Shakey Quazi, Christian Pehmoller, Mara Monetti, J.P. Fortin, Morris Birnbaum
The neuropeptide Urocortin 2 (UCN2) acts as a ligand for the G protein-coupled receptor (GPCR) corticotropin-releasing hormone receptor 2 (CRHR2) expressed in the brain and peripheral metabolic tissues. UCN2 has been reported to improve or worsen ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53be0724db1bb41f37b802e65ad1386f
https://doi.org/10.21203/rs.3.rs-2170419/v1
https://doi.org/10.21203/rs.3.rs-2170419/v1
Autor:
Adam C. Swensen, Dušan Veličković, Sarah M. Williams, Ronald J. Moore, Le Z. Day, Sherry Niessen, Sarah Hennessy, Camilo Posso, Mara Monetti, Wei-Jun Qian, Jon Jacobs, Laurence Whiteley, Ying Zhu, Paul D. Piehowski
Publikováno v:
Molecularcellular proteomics : MCP. 21(12)
Despite their diminutive size, islets of Langerhans play a large role in maintaining systemic energy balance in the body. New technologies have enabled us to go from studying the whole pancreas to isolated whole islets, to partial islet sections, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c8c408b83a112b27478b8b5393cd0f
https://pubmed.ncbi.nlm.nih.gov/36244662
https://pubmed.ncbi.nlm.nih.gov/36244662
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 11, Pp 2388-2397 (2005)
Acyl-CoA-dependent O-acyltransferases catalyze reactions in which fatty acyl-CoAs are joined to acyl acceptors containing free hydroxyl groups to produce neutral lipids. In this report, we characterize a human multifunctional O-acyltransferase (desig
Externí odkaz:
https://doaj.org/article/448609ea5dec4569a44913c37062d9f2
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 7, Pp 1502-1511 (2005)
The final step of triacylglycerol biosynthesis is catalyzed by acyl CoA:diacylglycerol acyltransferase (DGAT) enzymes. The two known DGATs, DGAT1 and DGAT2, are encoded by unrelated genes. Although both DGAT1 and DGAT2 knockout mice have reduced tiss
Externí odkaz:
https://doaj.org/article/d5de47878c1e4a0fb024b63c81d68620
Autor:
James D. Lord, Mara Monetti, Flora Martz, Ramya Kongala, Caitlyn Dickinson, Jeffrey A. Culver, Isac Lee, Scott Jelinsky, Marion Kasaian
Publikováno v:
Gastroenterology. 162:S-517
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::909f7d60b436d77fb3d671e5bb06a60d
https://doi.org/10.1016/s0016-5085(22)61229-0
https://doi.org/10.1016/s0016-5085(22)61229-0
Autor:
Jessica Ward, Jason Barricklow, Chuong Nguyen, Eliza Bollinger, Christopher T. Salatto, Bina Albuquerque, Mara Monetti, Norimitsu Shirai, Emily A. Day, Emily Cokorinos, Kieran F. Geoghegan, Gregory R. Steinberg, Rob Moccia, Matthew Peloquin, Ryan M. Esquejo, Morris J. Birnbaum, Russell A. Miller, Alan C. Opsahl, Brennan K. Smith, Jake Delmore, Kimberly O. Cameron, Timothy F. Osborne, Allan R. Reyes, John M. Kreeger, Lynne Butler, David A. Tess, Amit S. Kalgutkar, Yuji Shi
Publikováno v:
EBioMedicine, Vol 31, Iss, Pp 122-132 (2018)
EBioMedicine
EBioMedicine
Dysregulation of hepatic lipid and cholesterol metabolism is a significant contributor to cardiometabolic health, resulting in excessive liver lipid accumulation and ultimately non-alcoholic steatohepatitis (NASH). Therapeutic activators of the AMP-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f1c5af9f8bcc8ab432732a5031a0fe
http://www.sciencedirect.com/science/article/pii/S2352396418301373
http://www.sciencedirect.com/science/article/pii/S2352396418301373