Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Mar Valés-Gómez"'
Autor:
María-José Felgueres, Gloria Esteso, Álvaro F. García-Jiménez, Ana Dopazo, Nacho Aguiló, Carmen Mestre-Durán, Luis Martínez-Piñeiro, Antonio Pérez-Martínez, Hugh T. Reyburn, Mar Valés-Gómez
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The short-lived nature and heterogeneity of Natural Killer (NK) cells limit the development of NK cell-based therapies, despite their proven safety and efficacy against cancer. Here, we describe the biological basis, detailed phenotype and f
Externí odkaz:
https://doaj.org/article/bd24417e2d61481aba2a499fb276ab1b
Autor:
Eduardo Moreo, Aitor Jarit-Cabanillas, Iñaki Robles-Vera, Santiago Uranga, Claudia Guerrero, Ana Belén Gómez, Pablo Mata-Martínez, Luna Minute, Miguel Araujo-Voces, María José Felgueres, Gloria Esteso, Iratxe Uranga-Murillo, Maykel Arias, Julián Pardo, Carlos Martín, Mar Valés-Gómez, Carlos del Fresno, David Sancho, Nacho Aguiló
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Intravesical administration of Bacillus Calmette-Guérin (BCG) was one of the first FDA-approved immunotherapies and remains a standard treatment for bladder cancer. Previous studies have demonstrated that intravenous (IV) administration of
Externí odkaz:
https://doaj.org/article/cddf6509eb5149ae82e3ae71ebde6322
Autor:
Daniel Fernández-Soto, Álvaro F. García-Jiménez, José M. Casasnovas, Mar Valés-Gómez, Hugh T. Reyburn
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionIt is now clear that coronavirus disease 19 (COVID-19) severity is associated with a dysregulated immune response, but the relative contributions of different immune cells is still not fully understood. SARS CoV-2 infection triggers marke
Externí odkaz:
https://doaj.org/article/393746ad871c479da14e43b119e05dbb
Autor:
Gloria Esteso, María José Felgueres, Álvaro F. García-Jiménez, Christina Reyburn-Valés, Alberto Benguría, Enrique Vázquez, Hugh T. Reyburn, Nacho Aguiló, Carlos Martín, Eugenia Puentes, Ingrid Murillo, Esteban Rodríguez, Mar Valés-Gómez
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTBacillus Calmette-Guérin (BCG), the nonpathogenic Mycobacterium bovis strain used as tuberculosis vaccine, has been successfully used as treatment for non-muscle invasive bladder cancer for decades, and suggested to potentiate cellular and h
Externí odkaz:
https://doaj.org/article/d8013a98d0e348c39add8c2094c07125
Autor:
Marta Ibáñez-Navarro, Adrián Fernández, Adela Escudero, Gloria Esteso, Carmen Campos-Silva, Miguel Ángel Navarro-Aguadero, Alejandra Leivas, Beatriz Ruz Caracuel, Carlos Rodríguez-Antolín, Alejandra Ortiz, Alfonso Navarro-Zapata, Carmen Mestre-Durán, Manuel Izquierdo, María Balaguer-Pérez, Cristina Ferreras, Joaquín Martínez-López, Mar Valés-Gómez, Antonio Pérez-Martínez, Lucía Fernández
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionRefractory/relapsed pediatric acute leukemia are still clinically challenging and new therapeutic strategies are needed. Interactions between Natural Killer Group 2D (NKG2D) receptor, expressed in cytotoxic immune cells, and its ligands (
Externí odkaz:
https://doaj.org/article/a050597990ec4b1fb78353f27eb60db9
Autor:
José A. López‐Guerrero, Mar Valés‐Gómez, Francesc E. Borrás, Juan Manuel Falcón‐Pérez, María J. Vicent, María Yáñez‐Mó
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 4, Pp n/a-n/a (2023)
Abstract The standardization of clinical studies using extracellular vesicles (EVs) has mainly focused on the procedures employed for their isolation and characterization; however, preanalytical aspects of sample collection, handling and storage also
Externí odkaz:
https://doaj.org/article/666db4acea554510b03398aa4a00f80f
Autor:
Carmen Campos-Silva, Yaiza Cáceres-Martell, Estela Sánchez-Herrero, Amaia Sandúa, Alexandra Beneitez-Martínez, Álvaro González, Mariano Provencio, Atocha Romero, Ricardo Jara-Acevedo, María Yáñez-Mó, Mar Valés‐Gómez
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Extracellular vesicles (EVs), released by most cell types, provide an excellent source of biomarkers in biological fluids. However, in order to perform validation studies and screenings of patient samples, it is still necessary to
Externí odkaz:
https://doaj.org/article/bbd998c3323048ad8dcf39911a6e293e
Autor:
Silvia López-Borrego, Carmen Campos-Silva, Amaia Sandúa, Tamara Camino, Lucía Téllez-Pérez, Estibaliz Alegre, Alexandra Beneitez, Ricardo Jara-Acevedo, Annette Paschen, María Pardo, Álvaro González, Mar Valés-Gómez
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Metastatic melanoma presents, in many cases, oncogenic mutations in BRAF, a MAPK involved in proliferation of tumour cells. BRAF inhibitors, used as therapy in patients with these mutations, often lead to tumour resistance and, thus, the use of MEK i
Externí odkaz:
https://doaj.org/article/ccae7520204c4adea8ac07141197c0b3
Autor:
Eva Castellano, Célia Samba, Gloria Esteso, Laura Simpson, Elena Vendrame, Eva M. García‐Cuesta, Sheila López‐Cobo, Mario Álvarez-Maestro, Ana Linares, Asier Leibar, Thanmayi Ranganath, Hugh T. Reyburn, Luis Martínez‐Piñeiro, Catherine Blish, Mar Valés‐Gómez
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
High grade non-muscle-invasive bladder tumours are treated with transurethral resection followed by recurrent intravesical instillations of Bacillus Calmette Guérin (BCG). Although most bladder cancer patients respond well to BCG, there is no clinic
Externí odkaz:
https://doaj.org/article/86d96bbb33ea4821b94baed32ef23626
Autor:
Laura Esparcia-Pinedo, Pedro Martínez-Fleta, Noelia Ropero, Paula Vera-Tomé, Hugh T. Reyburn, José M. Casasnovas, José M. Rodríguez Frade, Mar Valés-Gómez, Carlos Vilches, Enrique Martín-Gayo, Cecilia Muñoz-Calleja, Francisco Sanchez-Madrid, Arantzazu Alfranca
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
The immune response promoted by SARS-CoV-2 vaccination is relevant to develop novel vaccines and optimized prevention strategies. We analyzed the adaptive immunity in healthy donors (HD) and convalescent individuals (CD), before and after administeri
Externí odkaz:
https://doaj.org/article/d34926fd15f940b6baccf9a59e57ba16