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Akademický článek
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Publikováno v:
Macromolecular Bioscience. 11:1378-1386
Topographic surface patterning of intrinsically non-adhesive P(EO-stat-PO)-based hydrogels can lead to the adhesion and spreading of fibroblasts. Explanations for this unexpected behavior are discussed, particularly with regard to non-specific protei
Publikováno v:
Biomaterials. 31:8583-8595
We present a systematic study of a perfluoropolyether (PFPE)-based elastomer as a new biomaterial. Besides its excellent long-term stability and inertness, PFPE can be decorated with topographical surface structures by replica molding. Micrometer-siz
Publikováno v:
Biomacromolecules. 11:3375-3383
Biomaterials that prevent nonspecific protein adsorption and cell adhesion are of high relevance for diverse applications in tissue engineering and diagnostics. One of the most widely applied materials for this purpose is Poly(ethylene glycol) (PEG).
Publikováno v:
Small. 5:2756-2760
A simple, soft nanolithographic method is used to fabricate sub-10-nm structures on star polyethylene glycol-based hydrogels and perfluoropolyether-based materials. Very small features, for example, gold nanoparticles of size approximately 8 nm with
Publikováno v:
Pure and Applied Chemistry. 80:2479-2487
Two UV-curable polymers, i.e., a star-shaped poly(ethylene glycol) (PEG) and a linear perfluorinated polyether (PFPE), are investigated as novel biomaterials in a systematic study of the cellular responses to surface chemistry, topography, and elasti
Publikováno v:
Biomaterials-Physics and Chemistry
This Chapter deals with bulk hydrogels consisting of a widely used biomaterial: poly(ethylene) glycol (PEG). PEG is renown for its bio-inertness; it is very effective in suppressing non-specific protein adsorption (NSPA) and thereby preventing cell a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff96fecfa58950467ba13771ce707e6a
https://doi.org/10.5772/24273
https://doi.org/10.5772/24273
Autor:
Marga C. Lensen, Mar Diez, Paolo A. Netti, Maurizio Ventre, Vera A. Schulte, Francesco Mollica, Claudia M. Cesa, Martin Möller, Filippo Stefanoni, Carlo F. Natale, Jingyu Chen
We present an innovative and simple, soft UV lithographic method “FIll-Molding In Capillaries” (FIMIC) that combines soft lithography with capillary force driven filling of micro-channels to create smooth hydrogel substrates with a 2D micro-patte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a534eb2963f3ab281ecb1956f935fb4
http://hdl.handle.net/11392/1513313
http://hdl.handle.net/11392/1513313
Autor:
Mar Diez, Nora E. Paul, Matthias Bartneck, Vera A. Schulte, Marga C. Lensen, Gabriele Zwadlo-Klarwasser
Publikováno v:
Acta biomaterialia. 6(10)
In this study, we investigated the influence of different perfluoropolyether (PFPE) microstructures on the inflammatory response of human macrophages. We generated four different microstructured PFPE surfaces by replica molding from silicon masters.
Publikováno v:
Biomacromolecules. 10(10)
Important in developing new biomaterials is the prevention of unspecific protein adsorption and cell interactions that in vivo can lead to a foreign body reaction. On the other hand, the material should support the growth of a specific cell type in a