Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Mar Abad"'
Autor:
Sara Ortiz-Rivero, Ana Peleteiro-Vigil, Lorena Abete, Elisa Lozano, Helen S. Hammer, Silvia Di Giacomo, Mar Abad, Loreto Boix, Alejandro Forner, Maria Reig, Rocio I.R. Macias, Oliver Pötz, Jose J.G. Marin, Oscar Briz
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116038- (2024)
Cholangiocarcinomas (CCAs) are cancers originated in the biliary tree, which are characterized by their high mortality and marked chemoresistance, partly due to the activity of ATP-binding cassette (ABC) export pumps, whose inhibition has been propos
Externí odkaz:
https://doaj.org/article/b4843168fecc49a9b5509ab1be898085
Autor:
Juan Carlos Montero, Sofía del Carmen, Mar Abad, José M. Sayagués, Antonio Barbáchano, Asunción Fernández-Barral, Alberto Muñoz, Atanasio Pandiella
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Advanced colorectal cancer (CRC) is difficult to treat. For that reason, the development of novel therapeutics is necessary. Here we describe a potentially actionable plasma membrane target, the amino acid transporter protein subu
Externí odkaz:
https://doaj.org/article/c928802677e94dfa89c009de97d2c610
Autor:
Adrián Sánchez-Fdez, Sofía Matilla-Almazán, Sofía Del Carmen, Mar Abad, Elena Arconada-Luque, Jaime Jiménez-Suárez, Luis Miguel Chinchilla-Tábora, Mª José Ruíz-Hidalgo, Ricardo Sánchez-Prieto, Atanasio Pandiella, Azucena Esparís-Ogando
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 6, Pp 1247-1257 (2023)
Abstract Sarcomas constitute a heterogeneous group of rare and difficult-to-treat tumors that can affect people of all ages, representing one of the most common forms of cancer in childhood and adolescence. Little is known about the molecular entitie
Externí odkaz:
https://doaj.org/article/9bdc60da83ee4acf9a344351e6a1c4e5
Autor:
Paula Sanchon-Sanchez, Oscar Briz, Rocio I.R. Macias, Mar Abad, Anabel Sanchez-Martin, Jose J.G. Marin, Elisa Lozano
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115658- (2023)
Background: Cholangiocarcinoma (CCA) is a highly lethal cancer originated in the biliary tree. Available treatments for CCA are scarcely effective, partly due to mechanisms of chemoresistance, such as aberrant activation of Wnt/β-catenin pathway and
Externí odkaz:
https://doaj.org/article/e797006f33624a438f7af18324ca912f
Autor:
Adrián Sánchez‐Fdez, Sofía Matilla‐Almazán, Juan Carlos Montero, Sofía Del Carmen, Mar Abad, Sara García‐Alonso, Somshuvra Bhattacharya, Kristin Calar, Pilar de la Puente, Alberto Ocaña, Atanasio Pandiella, Azucena Esparís‐Ogando
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 4, Pp n/a-n/a (2023)
Abstract Background The dismal prognosis of advanced ovarian cancer calls for the development of novel therapies to improve disease outcome. In this regard, we set out to discover new molecular entities and to assess the preclinical effectiveness of
Externí odkaz:
https://doaj.org/article/f594c2dfb3ea40f9b09fd0e75cb500ec
Autor:
Juan Carlos Montero, Elisa Calvo-Jiménez, Sofía del Carmen, Mar Abad, Alberto Ocaña, Atanasio Pandiella
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-16 (2022)
Abstract Background Despite the incorporation of novel therapeutics, advanced triple negative breast cancer (TNBC) still represents a relevant clinical problem. Considering this, as well as the clinical efficacy of antibody-drug conjugates (ADCs), we
Externí odkaz:
https://doaj.org/article/4f993c2abfac46199a9b964282d2c6f6
Autor:
Jonnathan Roldan Ruiz, Marta Gracia Fuentes Gago, Luis Miguel Chinchilla Tabora, Idalia Gonzalez Morais, José María Sayagués, Mar Abad Hernández, Maria Rosa Cordovilla Pérez, Maria Dolores Ludeña de la Cruz, Edel del Barco Morillo, Marta Rodriguez Gonzalez
Publikováno v:
Diagnostics, Vol 13, Iss 14, p 2347 (2023)
In recent years, non-small cell lung cancer treatment has been revolutionized. EGFR tyrosine kinase inhibitors and our improved understanding of its alterations have driven new diagnostic strategies. Liquid biopsies have emerged as a useful tool in t
Externí odkaz:
https://doaj.org/article/1f7f77d1983e4c0ca29bc13e920c86a2
Autor:
José María Sayagués, Juan Carlos Montero, Andrea Jiménez-Pérez, Sofía del Carmen, Marta Rodríguez, Rosario Vidal Tocino, Enrique Montero, Julia Sanz, Mar Abad
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8438 (2023)
Sporadic colorectal cancer (sCRC) initially presents as metastatic tumors in 25–30% of patients. The 5-year overall survival (OS) in patients with metastatic sCRC is 50%, falling to 10% in patients presenting with synchronous metastatic disease (st
Externí odkaz:
https://doaj.org/article/7c1c7bc7d7f44ba580d523f59eca9ebb
Autor:
Alba Rodriguez, Luís Antonio Corchete, José Antonio Alcazar, Juan Carlos Montero, Marta Rodriguez, Luis Miguel Chinchilla-Tábora, Rosario Vidal Tocino, Carlos Moyano, Saray Muñoz-Bravo, José María Sayagués, Mar Abad
Publikováno v:
Cancers, Vol 14, Iss 17, p 4076 (2022)
Despite advances in recent years in the study of the molecular profile of sporadic colorectal cancer (sCRC), the specific genetic events that lead to increased aggressiveness or the development of the metastatic process of tumours are not yet clear.
Externí odkaz:
https://doaj.org/article/4923115732bc41c2aab2486c04375ee2
Autor:
Sofía del Carmen, Luís Antonio Corchete, Cristina González Velasco, Julia Sanz, José Antonio Alcazar, Jacinto García, Ana Isabel Rodríguez, Rosario Vidal Tocino, Alba Rodriguez, Luis Alberto Pérez-Romasanta, José María Sayagués, Mar Abad
Publikováno v:
Cancers, Vol 13, Iss 13, p 3166 (2021)
Administering preoperative radiochemotherapy (RCT) in stage II-III tumors to locally advanced rectal carcinoma patients has proved to be effective in a high percentage of cases. Despite this, 20–30% of patients show no response or even disease prog
Externí odkaz:
https://doaj.org/article/2d4c7880f8304b5f908520b0ec1a9c9b