flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response.

Autor: Wang ZY; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Ludwigstrasse 43, 61231 Bad Nauheim, Germany.; German Centre for Cardiovascular Research (DZHK) Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.; Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany., Mehra A; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Ludwigstrasse 43, 61231 Bad Nauheim, Germany.; German Centre for Cardiovascular Research (DZHK) Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.; Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany., Wang QC; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Ludwigstrasse 43, 61231 Bad Nauheim, Germany.; German Centre for Cardiovascular Research (DZHK) Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.; Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany., Gupta S; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Ludwigstrasse 43, 61231 Bad Nauheim, Germany.; German Centre for Cardiovascular Research (DZHK) Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.; Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany., Ribeiro da Silva A; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Ludwigstrasse 43, 61231 Bad Nauheim, Germany.; German Centre for Cardiovascular Research (DZHK) Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.; Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany., Juan T; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Ludwigstrasse 43, 61231 Bad Nauheim, Germany.; German Centre for Cardiovascular Research (DZHK) Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.; Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany., Günther S; German Centre for Cardiovascular Research (DZHK) Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.; Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.; Bioinformatics and Deep Sequencing Platform, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany., Looso M; German Centre for Cardiovascular Research (DZHK) Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.; Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.; Bioinformatics Core Unit (BCU), Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany., Detleffsen J; German Centre for Cardiovascular Research (DZHK) Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.; Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.; Bioinformatics Core Unit (BCU), Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany., Stainier DYR; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Ludwigstrasse 43, 61231 Bad Nauheim, Germany.; German Centre for Cardiovascular Research (DZHK) Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.; Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany., Marín-Juez R; Centre Hospitalier Universitaire Sainte-Justine Research Center, 3175 Chemin de la Côte-Sainte-Catherine, H3T 1C5 Montréal, QC, Canada.; Department of Pathology and Cell Biology, Faculty of Medicine, Université de Montréal, H3T 1J4 Montréal, QC, Canada.

Publikováno v: Development (Cambridge, England) [Development] 2024 Dec 01; Vol. 151 (23). Date of Electronic Publication: 2024 Nov 29.

HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development

Autor: Gauvrit, S, Villasenor, A, Strilic, B, Kitchen, P, Collins, MM, Marín-Juez, R, Guenther, S, Maischein, HM, Fukuda, N, Canham, MA, Brickman, JM, Bogue, CW, Stainier, DYR

Formation of the lymphatic system requires the coordinated expression of several key regulators: vascular endothelial growth factor C (VEGFC), its receptor FLT4, and a key transcriptional effector, PROX1. Yet, how expression of these signaling compon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::9a08faa9183e91afa8ea347c3346fa24
https://publications.aston.ac.uk/id/eprint/39481/1/s41467_018_05039_1.pdf

The stress responsive gene ankrd1a is dynamically regulated during skeletal muscle development and upregulated following cardiac injury in border zone cardiomyocytes in adult zebrafish.

Autor: Boskovic S; Institute of Molecular Genetics and Genetic Engineering, Laboratory for Molecular Biology, University of Belgrade, 11042 Belgrade, Serbia. Electronic address: srdjanb@imgge.bg.ac.rs., Marín Juez R; Max Planck Institute for Heart and Lung Research, Department of Developmental Genetics, 61231 Bad Nauheim, Germany., Stamenkovic N; Institute of Molecular Genetics and Genetic Engineering, Laboratory for Molecular Biology, University of Belgrade, 11042 Belgrade, Serbia., Radojkovic D; Institute of Molecular Genetics and Genetic Engineering, Laboratory for Molecular Biology, University of Belgrade, 11042 Belgrade, Serbia., Stainier DY; Max Planck Institute for Heart and Lung Research, Department of Developmental Genetics, 61231 Bad Nauheim, Germany., Kojic S; Institute of Molecular Genetics and Genetic Engineering, Laboratory for Molecular Biology, University of Belgrade, 11042 Belgrade, Serbia. Electronic address: snezanakojic@imgge.bg.ac.rs.

Publikováno v: Gene [Gene] 2021 Aug 05; Vol. 792, pp. 145725. Date of Electronic Publication: 2021 May 16.

Conserved glucokinase regulation in zebrafish confirms therapeutic utility for pharmacologic modulation in diabetes.

Autor: Schmitner, Nicole¹ (AUTHOR) nicole.schmitner@uibk.ac.at, Thumer, Sophie¹ (AUTHOR), Regele, Dominik¹ (AUTHOR), Mayer, Elena¹ (AUTHOR), Bergerweiss, Ines¹ (AUTHOR), Helker, Christian^2,3 (AUTHOR), Stainier, Didier Y. R.² (AUTHOR), Meyer, Dirk¹ (AUTHOR), Kimmel, Robin A.¹ (AUTHOR)

Publikováno v: Communications Biology. 11/23/2024, Vol. 7 Issue 1, p1-11. 11p.

Stimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish.

Autor: Fukuda R; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; The German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Marín-Juez R; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; The German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., El-Sammak H; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; The German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Beisaw A; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; The German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Ramadass R; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; The German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Kuenne C; The Cardio-Pulmonary Institute (CPI) and Deep Sequencing Platform, Bad Nauheim, Germany., Guenther S; The Cardio-Pulmonary Institute (CPI) and Deep Sequencing Platform, Bad Nauheim, Germany.; Bioinformatics and Deep Sequencing Platform, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Konzer A; The German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; Biomolecular Mass Spectrometry, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Bhagwat AM; The German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; Biomolecular Mass Spectrometry, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Graumann J; The German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; Biomolecular Mass Spectrometry, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., Stainier DY; Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.; The German Centre for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.

Publikováno v: EMBO reports [EMBO Rep] 2020 Aug 05; Vol. 21 (8), pp. e49752. Date of Electronic Publication: 2020 Jul 09.