Zobrazeno 1 - 10
of 12
pro vyhledávání: '"María-Angeles Navas"'
Autor:
Miranda Bueno-Arribas, Celia Cruz-Cuevas, María-Angeles Navas, Ricardo Escalante, Olivier Vincent
Publikováno v:
Open Biology, Vol 13, Iss 11 (2023)
PROPPINs/WIPIs are β-propeller proteins that bind phosphoinositides and contribute to the recruitment of protein complexes involved in membrane remodelling processes such as autophagosome formation and endosomal trafficking. Yeast Atg21 and mammalia
Externí odkaz:
https://doaj.org/article/5edee1f599ae4b589d346ba4199ab088
Autor:
Carmen-María García-Herrero, Oscar Rubio-Cabezas, Sharona Azriel, Angel Gutierrez-Nogués, Angel Aragonés, Olivier Vincent, Angel Campos-Barros, Jesús Argente, María-Angeles Navas
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30518 (2012)
Glucokinase (GK) acts as a glucose sensor in the pancreatic beta-cell and regulates insulin secretion. Heterozygous mutations in the human GK-encoding GCK gene that reduce the activity index increase the glucose-stimulated insulin secretion threshold
Externí odkaz:
https://doaj.org/article/922a1fa58b42429c864ff12388c797d1
Autor:
María-Angeles Navas, Miranda Bueno-Arribas, Celia Cruz-Cuevas, Olivier Vincent, Irene Blanca, Ricardo Escalante
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Human Molecular Genetics
instname
Human Molecular Genetics
© The Author(s) 2021.
PROPPINs are phosphoinositide-binding β-propeller proteins that mediate membrane recruitment of other proteins and are involved in different membrane remodeling processes. The main role of PROPPINs is their function in au
PROPPINs are phosphoinositide-binding β-propeller proteins that mediate membrane recruitment of other proteins and are involved in different membrane remodeling processes. The main role of PROPPINs is their function in au
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5ebb428ffb8c363a0611b96fc3131b
http://hdl.handle.net/10261/264776
http://hdl.handle.net/10261/264776
Autor:
Miranda Bueno-Arribas, Ricardo Escalante, María-Angeles Navas, Alba Tornero-Écija, Laura Antón-Esteban, Olivier Vincent
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
© 2021 Vincent, Antón-Esteban, Bueno-Arribas, Tornero-Écija, Navas and Escalante.
WIPIs are a conserved family of proteins with a characteristic 7-bladed β-propeller structure. They play a prominent role in autophagy, but also in other membr
WIPIs are a conserved family of proteins with a characteristic 7-bladed β-propeller structure. They play a prominent role in autophagy, but also in other membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5879044591986e1e0c7719a6dd1743f1
http://hdl.handle.net/10261/265590
http://hdl.handle.net/10261/265590
Autor:
Angel Gutierrez-Nogués, Luis Castaño, Amaia Vela, María-Angeles Navas, Rosa de Diego Martínez, Teresa Velayos, Concepción Fernández-Ramos
Publikováno v:
Clinical Endocrinology. 86:778-783
SummaryBackground Mutations in the GCK gene lead to different forms of glucokinase (GCK)-disease, activating mutations cause hyperinsulinaemic hypoglycaemia while inactivating mutations cause monogenic diabetes. Hyperinsulinism (HI) is a heterogeneou
Autor:
Carmen-María García-Herrero, Angel Gutierrez-Nogués, Josep Oriola, María-Angeles Navas, Olivier Vincent
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Glucokinase (GCK) plays a key role in glucose homeostasis. Heterozygous inactivating mutations in the GCK gene cause the familial, mild fasting hyperglycaemia named MODY2. Besides its particular kinetic characteristics, glucokinase is regulated by su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d495a0609ee9d83aac00c83478a0d08
http://hdl.handle.net/10261/188201
http://hdl.handle.net/10261/188201
Autor:
María-Angeles Navas, Carmen-María García-Herrero, Sara León, Josep Oriola, Angel Gutierrez-Nogués, Francisca Moreno, Olivier Vincent
Publikováno v:
JIMD Reports ISBN: 9783662466995
Hypoglycaemic drugs that close the KATP channel have been tested in patients with permanent neonatal diabetes due to glucokinase mutations (PNDM-GCK). From the results obtained, it has been suggested that this treatment may be beneficial in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39fa3d83faec90fce2f5d6531c7a5bf0
https://doi.org/10.1007/8904_2014_383
https://doi.org/10.1007/8904_2014_383
Autor:
Victor-Manuel Andía, Sharona Azriel, Manuel Gargallo, Juan-Jose Gorgojo, María Galán, María-Angeles Navas, Maria Durán, Carmen-María García-Herrero
Publikováno v:
Molecular medicine (Cambridge, Mass.). 17(3-4)
Hepatocyte nuclear factor 1-α (HNF-1α) is a homeodomain transcription factor expressed in a variety of tissues (including liver and pancreas) that regulates a wide range of genes. Heterozygous mutations in the gene encoding HNF-1α (HNF1A) cause fa
Autor:
Sharona Azriel, Isabel Roncero, Elías Delgado-Alvarez, María Galán, Olivier Vincent, Enrique Blázquez, Pedro Boix-Pallares, Francisco Díaz-Cadórniga, María-Angeles Navas
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
8 pages, 4 figures, 3 tables.
Glucokinase acts as the pancreatic glucose sensor and plays a critical role in the regulation of insulin secretion by the b-cell. Heterozygous mutations in the glucokinase-encoding GCK gene, which result in a reduct
Glucokinase acts as the pancreatic glucose sensor and plays a critical role in the regulation of insulin secretion by the b-cell. Heterozygous mutations in the glucokinase-encoding GCK gene, which result in a reduct
Autor:
Olivier Vincent, Laura Antón-Esteban, Miranda Bueno-Arribas, Alba Tornero-Écija, María-Ángeles Navas, Ricardo Escalante
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
WIPIs are a conserved family of proteins with a characteristic 7-bladed β-propeller structure. They play a prominent role in autophagy, but also in other membrane trafficking processes. Mutations in human WIPI4 cause several neurodegenerative diseas
Externí odkaz:
https://doaj.org/article/6b779457268749cea266ff1a9f2b516a