Purification of Recombinant Galectins Expressed in Bacteria

Autor: Cecilia Arahí Prato, Julieta Carabelli, Valentina Cattaneo, Oscar Campetella, María Virginia Tribulatti

Publikováno v: STAR Protocols, Vol 1, Iss 3, Pp 100204- (2020)

Summary: Galectins are soluble lectins that participate in many physiological and pathological functions. Since they can act extracellularly, the use of the recombinant protein is a recurrent strategy for studying their biological functions. Here, we

Externí odkaz: https://doaj.org/article/b50a5181e4684aaa9bfe29f83d26b75c

Control of angiogenesis by galectins involves the release of platelet-derived proangiogenic factors.

Autor: Julia Etulain, Soledad Negrotto, María Virginia Tribulatti, Diego Omar Croci, Julieta Carabelli, Oscar Campetella, Gabriel Adrián Rabinovich, Mirta Schattner

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e96402 (2014)

Platelets contribute to vessel formation through the release of angiogenesis-modulating factors stored in their α-granules. Galectins, a family of lectins that bind β-galactoside residues, are up-regulated in inflammatory and cancerous tissues, tri

Externí odkaz: https://doaj.org/article/a6052c8274e247d0b2b57f8fa82b9490

The inflammatory response induced by Pseudomonas aeruginosa in macrophages enhances apoptotic cell removal

Autor: Paula Arias, Adriana V. Jäger, Marcela Adriana Brocco, Maria Victoria Pepe, Arlinet Kierbel, María Virginia Tribulatti

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports

Pathogens phagocytosis and the uptake of apoptotic cells (efferocytosis) are essential macrophages tasks, classically considered as mutually exclusive. Macrophages have been observed to polarize into either pro-inflammatory/microbicidal or anti-infla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cacf6e7f4fd743e09fa43466305bae
https://doi.org/10.1038/s41598-021-81557-1

Optimized adenoviral vector that enhances the assembly of FMDV O1 virus-like particles in situ increases its potential as vaccine for serotype O viruses

Autor: Micaela Ziraldo, María Virginia Tribulatti, Nora Mattion, Cecilia A. Prato, Patricia Ines Zamorano, Alejandra D'Antuono, Juan Esteban Bidart

Publikováno v: Frontiers in Microbiology 11 : 591019 (Noviembre 2020)
INTA Digital (INTA)
Instituto Nacional de Tecnología Agropecuaria
instacron:INTA
Frontiers in Microbiology, Vol 11 (2020)

Although replication-defective human adenovirus type 5 (Ad5) vectors that express in situ the capsid-encoding region of foot-and-mouth disease virus (FMDV) have been proven to be effective as vaccines in relevant species for several viral strains, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f897275ca902d21f64ad88ebd39b227
https://www.frontiersin.org/articles/10.3389/fmicb.2020.591019/full

Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer

Autor: Mario Di Matteo, Chiara Aldeni, Hans Prenen, Massimiliano Mazzone, Jo A. Van Ginderachter, Giuseppe Floris, Rosa Martín-Pérez, Melissa García-Caballero, Sotiria Pinioti, María Virginia Tribulatti, Samantha Pretto, Roel Kroes, Manuel Ehling, Ann Smeets, Pawel Bieniasz-Krzywiec, Oscar Campetella, Agnès Noël

Publikováno v: Cell Metabolism
Cell metabolism

Among mammary tumor-infiltrating immune cells, the highest expression of podoplanin (PDPN) is found in a subset of tumor-associated macrophages (TAMs). We hereby demonstrate that PDPN is involved in the attachment of this TAM subset to lymphatic endo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06372e4933b23619d57ac6677e50d331
https://lirias.kuleuven.be/handle/123456789/640612