Zobrazeno 1 - 10
of 15
pro vyhledávání: '"María Villalba Esparza"'
Autor:
Daniel Jiménez-Sánchez, Álvaro López-Janeiro, María Villalba-Esparza, Mikel Ariz, Ece Kadioglu, Ivan Masetto, Virginie Goubert, Maria D. Lozano, Ignacio Melero, David Hardisson, Carlos Ortiz-de-Solórzano, Carlos E. de Andrea
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Predicting recurrence in low-grade, early-stage endometrial cancer (EC) is both challenging and clinically relevant. We present a weakly-supervised deep learning framework, NaroNet, that can learn, without manual expert annotation, the compl
Externí odkaz:
https://doaj.org/article/a012ff9099484386aca7d1ea74f03ffa
Autor:
Daniel Meraviglia-Crivelli, Helena Villanueva, Angelina Zheleva, María Villalba-Esparza, Beatriz Moreno, Ashwathi Puravankara Menon, Alfonso Calvo, Javier Cebollero, Martin Barainka, Igor Ruiz de los Mozos, Carlos Huesa-Berral, Fernando Pastor
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-24 (2022)
Abstract Background The quality and quantity of tumor neoantigens derived from tumor mutations determines the fate of the immune response in cancer. Frameshift mutations elicit better tumor neoantigens, especially when they are not targeted by nonsen
Externí odkaz:
https://doaj.org/article/2e8fa14d44924374b4eb660bb5319ae9
Autor:
Daniel Meraviglia-Crivelli, Helena Villanueva, Ashwathi Puravankara Menon, Angelina Zheleva, Beatriz Moreno, María Villalba-Esparza, Fernando Pastor
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 413-425 (2022)
Immune-checkpoint blockade (ICB) therapy has changed the clinical outcome of many types of aggressive tumors, but there still remain many cancer patients that do not respond to these treatments. There is an unmet need to develop a feasible clinical t
Externí odkaz:
https://doaj.org/article/12638e60bd4c449d8adab68bb1e7c48d
Autor:
Amy R. Cross, Carlos E. de Andrea, María Villalba-Esparza, Manuel F. Landecho, Lucia Cerundolo, Praveen Weeratunga, Rachel E. Etherington, Laura Denney, Graham Ogg, Ling-Pei Ho, Ian S.D. Roberts, Joanna Hester, Paul Klenerman, Ignacio Melero, Stephen N. Sansom, Fadi Issa
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Severe lung damage resulting from COVID-19 involves complex interactions between diverse populations of immune and stromal cells. In this study, we used a spatial transcriptomics approach to delineate the cells, pathways, and genes present across the
Externí odkaz:
https://doaj.org/article/7096c4d58dbb4565a8572524c105e1a2
Autor:
Amy R. Cross, Carlos E. de Andrea, María Villalba-Esparza, Manuel F. Landecho, Lucia Cerundolo, Praveen Weeratunga, Rachel E. Etherington, Laura Denney, Graham Ogg, Ling-Pei Ho, Ian S.D. Roberts, Joanna Hester, Paul Klenerman, Ignacio Melero, Stephen N. Sansom, Fadi Issa
Publikováno v:
JCI insight.
Severe lung damage resulting from COVID-19 involves complex interactions between diverse populations of immune and stromal cells. In this study, we used a spatial transcriptomics approach to delineate the cells, pathways, and genes present across the
Autor:
Maria C. Ochoa, Carlos Ortiz-de-Solorzano, Maria E. Rodriguez-Ruiz, Iñaki Eguren-Santamaria, Marta Abengozar-Muela, Kurt A. Schalper, Mikel Ariz, Cristina Sainz, Sandra Sánchez-Gregorio, María Villalba-Esparza, Miguel F. Sanmamed, Saray Garasa, José I. Echeveste, Jose Luis Perez-Gracia, Alvaro Teijeira, Maria D. Lozano, Ignacio Melero, Carlos E. de Andrea
Publikováno v:
The Journal of Pathology. 255:190-201
Neutrophil extracellular traps (NETs) are webs of extracellular nuclear DNA extruded by dying neutrophils infiltrating tissue. NETs constitute a defence mechanism to entrap and kill fungi and bacteria. Tumours induce the formation of NETs to the adva
Autor:
Ignacio Melero, María Villalba-Esparza, Borja Recalde-Zamacona, Daniel Jiménez-Sánchez, Álvaro Teijeira, Alan Argueta, Laura García-Tobar, Laura Álvarez-Gigli, Cristina Sainz, David Garcia-Ros, Estefanía Toledo, Marta Abengozar-Muela, Mirian Fernández-Alonso, Mariano Rodríguez-Mateos, Gabriel Reina, Francisco Carmona-Torre, Jorge Augusto Quiroga, Jose L. Del Pozo, Amy Cross, Álvaro López-Janeiro, David Hardisson, José I. Echeveste, Maria D. Lozano, Ling-Pei Ho, Paul Klenerman, Fadi Issa, Manuel F. Landecho, Carlos E. de Andrea
Publikováno v:
Chest. 162(5)
Background Excessive inflammation is pathogenic in the pneumonitis associated with severe COVID-19. Neutrophils are among the most abundantly present leukocytes in the inflammatory infiltrates and may form neutrophil extracellular traps (NETs) under
Autor:
Alberto Berjón, Victoria Heredia-Soto, Ece Kadioglu, Andrés Redondo, Rodrigo Barderas, Marta Mendiola, Ignacio Ruz-Caracuel, Laura Yébenes, David Hardisson, J I Casal, Álvaro López-Janeiro, Vivian de los Ríos, Jorge L Ramón-Patino, Carlos E. de Andrea, María Villalba Esparza, Virginie Goubert, Alicia Hernández, Alberto Peláez-García, Ivan Masetto
Publikováno v:
Cancers
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
Biblos-e Archivo. Repositorio Institucional de la UAM
Volume 13
Issue 4
Cancers, Vol 13, Iss 794, p 794 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
Biblos-e Archivo. Repositorio Institucional de la UAM
Volume 13
Issue 4
Cancers, Vol 13, Iss 794, p 794 (2021)
16 p.-4 fig.
Low-grade, early-stage endometrial carcinoma (EC) is the most frequent malignant tumor of the uterine corpus. However, the molecular alterations that underlie these tumors are far from being fully understood. The purpose of this stu
Low-grade, early-stage endometrial carcinoma (EC) is the most frequent malignant tumor of the uterine corpus. However, the molecular alterations that underlie these tumors are far from being fully understood. The purpose of this stu
Autor:
Laura Álvarez-Gigli, Manu Landecho, Amy Cross, María Villalba-Esparza, Laura García-Tobar, Jorge Quiroga, Allan Argueta, Teijeira Álvaro, Estefanía Toledo, Maria Rodriguez-Moreno, Gabriel Reina, Ignacio Melero, Carlos E. de Andrea, Marta Abengozar-Muela, Ling-Pei Ho, Mirian Fernández-Alonso, Cristina Sainz, Francisco Carmona-Torre, Borja Recalde-Zamacona, José I. Echeveste, Paul Klenerman, Fadi Issa, David Garcia-Ros, José Luis del Pozo, Maria D. Lozano
Publikováno v:
SSRN Electronic Journal.
Background: Excessive inflammation is pathogenic in pneumonitis associated to severe COVID-19. Neutrophils are among the most abundantly present leukocytes in the inflammatory infiltrates and may form neutrophil extracellular traps (NETs) under the l
Autor:
Maria D. Lozano, María Villalba-Esparza, Laura Garcia Tobar, Marta Abengozar, Laura Alvarez, Carlos De Andrea
Publikováno v:
Journal of the American Society of Cytopathology. 10:S9-S10