Zobrazeno 1 - 10
of 55
pro vyhledávání: '"María T. Plaza"'
Autor:
Fernando Sánchez-Cantalejo, Isidoro Izquierdo, Francisco Franco, María T. Plaza, Juan A. Tamayo
Publikováno v:
Tetrahedron. 66:3788-3794
Naturally occurring (1 S ,2 R ,3 R ,5 R ,7a R )-1,2-dihydroxy-3-hydroxymethyl-5-methylpyrrolizidine [(+)-hyacinthacine A 6 , 2 ] together with unnatural (1 S ,2 R ,3 R ,7a S )-1,2-dihydroxy-3-hydroxymethylpyrrolizidine [(+)-7a- epi -hyacinthacine A 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2680651028e7630497f93b2b996c458
https://doi.org/10.1016/j.tet.2010.03.049
https://doi.org/10.1016/j.tet.2010.03.049
Publikováno v:
Synthesis. 2008:1373-1378
A series of naturally occurring pyrrolidine alkaloids and analogues, with the general structure of trideoxy-2,5-iminohexitols (imino- or azasugars), have been enantiosynthesized using triorthogonally protected pyrrolidines, previously prepared from c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bda156da6ba77c0eb41e8df771689620
https://doi.org/10.1055/s-2008-1072566
https://doi.org/10.1055/s-2008-1072566
Autor:
Isidoro Izquierdo, Fernando Sánchez-Cantalejo, Juan A. Tamayo, María T. Plaza, Francisco Franco
Publikováno v:
Tetrahedron. 64:4993-4998
Syntheses of 2,5,6-trideoxy-2,5-imino- d -alditol ( 2 , 6-deoxy-DADP) and its enantiomer ( 3 ) from tri-orthogonally protected derivatives of DADP have been developed employing lipase-mediated kinetic desymmetrization and protecting group manipulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5ca4e0d0ed83d73516396334505c8bc
https://doi.org/10.1016/j.tet.2008.03.089
https://doi.org/10.1016/j.tet.2008.03.089
Autor:
Fernando Sánchez-Cantalejo, María T. Plaza, Juan A. Tamayo, Isidoro Izquierdo, Víctor Yáñez, Daniele Lo Re
Publikováno v:
Tetrahedron. 64:4613-4618
A convergent synthesis of the naturally occurring alkaloid (−)-hyacinthacine A 7 , a glycosidase inhibitor of the pyrrolizidine class, is described. The homochiral starting material was tri-orthogonally protected DMDP 10 , derived from d -fructose.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7a796aeed1a138cf5f92cda004b1378
https://doi.org/10.1016/j.tet.2008.03.009
https://doi.org/10.1016/j.tet.2008.03.009
Publikováno v:
Tetrahedron: Asymmetry. 18:2211-2217
(1 R ,2 S ,3 R ,5 S ,7a R )-1,2-Dihydroxy-3-hydroxymethyl-5-methylpyrrolizidine 10 [(+)-5- epi hyacinthacine A 5 ] and (1 R ,2 S ,3 R ,5 S ,7a S )-1,2-dihydroxy-3-hydroxymethyl-5-methylpyrrolizidine 17 [ ent -5- epi hyacinthacine A 4 ] have been synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d911e340c4163482f239a8fb1804fb2
https://doi.org/10.1016/j.tetasy.2007.09.014
https://doi.org/10.1016/j.tetasy.2007.09.014
Publikováno v:
Tetrahedron. 63:1440-1447
The readily available 3-O-benzyl-1,2-O-isopropylidene-β- d -fructopyranose (2) was transformed into its 5-O- (3) and 4-O-benzoyl (4) derivative. Compound 4 was straightforwardly transformed into 5-azido-4-O-benzoyl-3-O-benzyl-5-deoxy-1,2-O-isopropyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a1e9ccf140706694611c0c72778b2b2
https://doi.org/10.1016/j.tet.2006.11.070
https://doi.org/10.1016/j.tet.2006.11.070
Publikováno v:
Tetrahedron. 62:6006-6011
(1R,2S,3S,5R,7aR)-1,2-Dihydroxy-3-hydroxymethyl-5-methylpyrrolizidine[(−)-3-epihyacinthacine A5, 1a] and (1S,2R,3R,5S 7aS)-1,2-dihydroxy-3-hydroxymethylpyrrolizidine[(+)-3-epihyacinthacine A5, 1b] have been synthesized either by Wittig's or Horner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b3f34298bbb45f50ab16bba3ffeba9d
https://doi.org/10.1016/j.tet.2006.04.003
https://doi.org/10.1016/j.tet.2006.04.003
Publikováno v:
Journal of Carbohydrate Chemistry. 25:281-295
A new synthetic approach to analogs of (+)‐casuarine (2a and 2b), a natural pentahydroxylated pyrrolizidinic alkaloid in a highly stereocontrolled manner, is reported herein. An orthogonally protected polyhydroxylated pyrrolidine, such as (2S,3R,4R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::317bb9ae9d22f8b9b0a27422d61c363c
https://doi.org/10.1080/07328300600735181
https://doi.org/10.1080/07328300600735181
Publikováno v:
Tetrahedron. 62:2693-2697
The readily available 3-O-benzoyl-4-O-benzyl-1,2-O-isopropylidene-5-O-methanesulfonyl-β- d -fructopyranose ( 5 ) was straightforwardly transformed into its d -psico epimer ( 8 ), after O-debenzoylation followed by oxidation and reduction, which caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eeb8d610b7026e0dd4e5af70924b781
https://doi.org/10.1016/j.tet.2005.12.023
https://doi.org/10.1016/j.tet.2005.12.023
Publikováno v:
Tetrahedron. 61:6527-6533
A new synthesis for (+)-casuarine ( 1 ) and its 6,7-diepi isomer ( 15 ) in a stereocontrolled manner, is reported herein. An appropriately protected polyhydroxylated pyrrolidine, such as (2R,3R,4R,5R)-3,4-dibenzyloxy-2′-O-tert-butyldiphenylsilyl-2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ff927b470741ffcf564246cc586a14
https://doi.org/10.1016/j.tet.2005.05.004
https://doi.org/10.1016/j.tet.2005.05.004