Zobrazeno 1 - 10
of 11
pro vyhledávání: '"María Sol Ballari"'
Autor:
María Sol Ballari, Exequiel O. J. Porta, Evelyn Arel Zalazar, Carla M. Borini Etichetti, José M. Padrón, Javier Girardini, Guillermo R. Labadie
Salirasib, or farnesylthiosalicylic acid (FTS), is a salicylic acid derivative with demonstrated antineoplastic activity. While designed as a competitor of the substrate S-farnesyl cysteine on Ras, it is a potent competitive inhibitor of isoprenylcys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49f0cbd3394d5a94130e6efdc3913f45
https://doi.org/10.26434/chemrxiv-2021-gkff1-v2
https://doi.org/10.26434/chemrxiv-2021-gkff1-v2
Autor:
Exequiel Porta, María Sol Ballari, Shane Wilkinson, Guoyi Ma, Babu Tekwani, Guillermo Labadie
A series of thirty 1,2,3-triazolylsterols, inspired by azasterols with proven antiparasitic activity, were prepared by a stereocontrolled synthesis. Ten of these compounds constitute chimeras/hybrids of AZA and 1,2,3-triazolyl azasterols. The entire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::925f4bd1e556e04345f1adc98213c2d4
https://doi.org/10.26434/chemrxiv-2021-q0q9v-v2
https://doi.org/10.26434/chemrxiv-2021-q0q9v-v2
Autor:
Exequiel O.J. Porta, María Sol Ballari, Renzo Carlucci, Shane Wilkinson, Guoyi Ma, Babu L. Tekwani, Guillermo R. Labadie
Publikováno v:
European Journal of Medicinal Chemistry. 254:115378
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e81f8fd1c665c6024cf60c103489cf74
https://doi.org/10.1016/j.ejmech.2023.115378
https://doi.org/10.1016/j.ejmech.2023.115378
A series of thirty 1,2,3-triazolylsterols were prepared by a stereocontrolled synthesis and inspired by azasterols with proven antiparasitic activity. Ten of these compounds constitute chimeras/hybrids of AZA and 1,2,3-triazolyl azasterols. The entir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84b65c70c67309917ed42460296e5f93
https://doi.org/10.26434/chemrxiv-2021-q0q9v
https://doi.org/10.26434/chemrxiv-2021-q0q9v
Autor:
Babu L. Tekwani, Exequiel O. J. Porta, María Sol Ballari, Shane R. Wilkinson, Guillermo R. Labadie
A series of thirty 1,2,3-triazolylsterols were prepared by a stereocontrolled synthesis and inspired by azasterols with proven antiparasitic activity. Ten of these compounds constitute chimeras/hybrids of AZA and 1,2,3-triazolyl azasterols. The entir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad0456c3d135fc940dfbe5719a96971f
https://doi.org/10.33774/chemrxiv-2021-q0q9v
https://doi.org/10.33774/chemrxiv-2021-q0q9v
Aim: We proposed to determine the antiproliferative activity of a series of synthetic salirasib analogs, presenting or not a 1,2,3-triazole linker, against five different cancer cell lines. Results: Bioassay, cheminformatic, and in silico ADME-Tox al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d482b9b67614dd4033f8c3de7daf1aa
https://doi.org/10.33774/chemrxiv-2021-gkff1
https://doi.org/10.33774/chemrxiv-2021-gkff1
Autor:
Ariel Mariano Silber, Lucas Pagura, Guillermo R. Labadie, Lucía Fargnoli, Julia A. Cricco, María Sol Ballari
Background: Proline is a fundamental amino acid for Trypanosoma cruzi, the etiological agent of Chagas disease. Proline is mainly incorporated from the extracellular medium by amino acid transport systems. Different proline analogues proved to intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4678526858abcaae6b93610658d4d4
https://doi.org/10.33774/chemrxiv-2021-l64kg
https://doi.org/10.33774/chemrxiv-2021-l64kg
Autor:
Ricardo Enrique Toso, César A.N. Catalán, Guillermo R. Labadie, María Sol Ballari, Hebe Lina Alvarez, Diego A. Sampietro, Cristina M Jimenez
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
This work aimed to identify secondary metabolites from aerial parts of Euphorbia species functional for control of toxigenic Fusarium species responsible of cereal grain rots. Methods and Results: Aerial parts of Euphorbia serpens, Euphorbia schicken
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efed220e4e9d310f47a3ec896ce0b2d1
https://pubmed.ncbi.nlm.nih.gov/32969574
https://pubmed.ncbi.nlm.nih.gov/32969574
Autor:
Luz Díaz-Storani, Jonathan B. Johnston, Andrea B. J. Bracca, Diego M. Moreno, Exequiel O. J. Porta, Anaelle A. Clary, María Sol Ballari, Guillermo R. Labadie
Publikováno v:
Bioorganic & Medicinal Chemistry. 44:116304
A series of C15-C20 isoprenyl derivatives bearing terminal alkenyl and alkynyl groups were synthesized as possible substrates of the methyl-branched lipid ω-hydroxylase CYP124A1 from Mycobacterium tuberculosis. The interactions of each compound with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b7917397fc41f2738121061cc30ea0
https://doi.org/10.1016/j.bmc.2021.116304
https://doi.org/10.1016/j.bmc.2021.116304
Autor:
Daniel Alberto Wunderlin, Ana N. Santiago, Gabriela Egly Feresin, María Sol Ballari, Natividad Herrera Cano, AG Lopez
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
A series of benzyl-substituted thiobenzoazoles were synthesized by an environmentally friendly 18 approach, to search for new antifungal agrochemicals. Compounds were prepared starting from 2- 19 mercaptobenzoazoles, using KOH, benzyl halides and wat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc623c19f6f1d940afccd811f4326b79
https://pubmed.ncbi.nlm.nih.gov/29099589
https://pubmed.ncbi.nlm.nih.gov/29099589