Zobrazeno 1 - 10
of 41
pro vyhledávání: '"María S, Soengas"'
Autor:
Odeta Meçe, Diede Houbaert, Maria-Livia Sassano, Tania Durré, Hannelore Maes, Marco Schaaf, Sanket More, Maarten Ganne, Melissa García-Caballero, Mila Borri, Jelle Verhoeven, Madhur Agrawal, Kathryn Jacobs, Gabriele Bergers, Silvia Blacher, Bart Ghesquière, Mieke Dewerchin, Johan V. Swinnen, Stefan Vinckier, María S. Soengas, Peter Carmeliet, Agnès Noël, Patrizia Agostinis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Autophagy is essential to endothelial cell homeostasis. Here the authors show that lipophagy in LEC supports fatty acid oxidation to sustain a mitochondrial-Prox1 gene expression circuit and promote response of LEC to lymphangiogenic mediators.
Externí odkaz:
https://doaj.org/article/6f053768112c4a3e957fc921d9943221
Autor:
David Olmeda, Daniela Cerezo‐Wallis, Cynthia Mucientes, Tonantzin G Calvo, Estela Cañón, Direna Alonso‐Curbelo, Nuria Ibarz, Javier Muñoz, José L Rodriguez‐Peralto, Pablo Ortiz‐Romero, Sagrario Ortega, María S Soengas
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 12, Pp 1-20 (2021)
Abstract Long‐range communication between tumor cells and the lymphatic vasculature defines competency for metastasis in different cancer types, particularly in melanoma. Nevertheless, the discovery of selective blockers of lymphovascular niches ha
Externí odkaz:
https://doaj.org/article/4c6a9e3ae90d4eed9a877b550a8917f5
Autor:
Metehan Cifdaloz, Lisa Osterloh, Osvaldo Graña, Erica Riveiro-Falkenbach, Pilar Ximénez-Embún, Javier Muñoz, Cristina Tejedo, Tonantzin G. Calvo, Panagiotis Karras, David Olmeda, Belén Miñana, Gonzalo Gómez-López, Estela Cañon, Eduardo Eyras, Haihong Guo, Ferdinand Kappes, Pablo L. Ortiz-Romero, Jose L. Rodríguez-Peralto, Diego Megías, Juan Valcárcel, María S. Soengas
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Hundreds of mRNA binding proteins (mRBPs) have been described in mammalian cells. Here, the authors identify RBPs differentially regulated in melanoma, and show the RBP CELF1 controlling a distinct set of protumorigenic factors.
Externí odkaz:
https://doaj.org/article/1340379aab9748ac8e9ce5a84d0a223c
Autor:
María S. Soengas, Scott W. Lowe, Anthony W. Opipari, Philipp Steiner, Jenny L. Rush, Thomas P. Miller, Monique Verhaegen, Yolanda Fernández
Supplementary Figures 1-6 from Differential Regulation of Noxa in Normal Melanocytes and Melanoma Cells by Proteasome Inhibition: Therapeutic Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e20a6c029aa98acfe3bb34be197c99
https://doi.org/10.1158/0008-5472.22363731.v1
https://doi.org/10.1158/0008-5472.22363731.v1
Autor:
María S. Soengas, Scott W. Lowe, Anthony W. Opipari, Philipp Steiner, Jenny L. Rush, Thomas P. Miller, Monique Verhaegen, Yolanda Fernández
Melanoma is the most aggressive form of skin cancer and advanced stages are invariably resistant to conventional therapeutic agents. Using bortezomib as a prototypic proteasome inhibitor, we have identified a novel and critical role of the proteasome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5185bd36acd00e2f9bc9c982dc96a617
https://doi.org/10.1158/0008-5472.c.6493857.v1
https://doi.org/10.1158/0008-5472.c.6493857.v1
Autor:
María S. Soengas, Shaomeng Wang, Carol R. Bradford, Thomas E. Carey, Matt Van Brocklin, James T. Elder, Rajan Nair, Audrey Bengtson, Zaneta Nikolovska-Coleska, J. Chadwick Brenner, Keith G. Wolter, Guoping Wang, Cristina Martín de la Vega, Joshua A. Bauer, Monique Verhaegen
Supplementary Figures 1-5 from A Novel BH3 Mimetic Reveals a Mitogen-Activated Protein Kinase–Dependent Mechanism of Melanoma Cell Death Controlled by p53 and Reactive Oxygen Species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65bb6e82596a38c226aef142a000a5c7
https://doi.org/10.1158/0008-5472.22367103.v1
https://doi.org/10.1158/0008-5472.22367103.v1
Autor:
María S. Soengas, Shaomeng Wang, Carol R. Bradford, Thomas E. Carey, Matt Van Brocklin, James T. Elder, Rajan Nair, Audrey Bengtson, Zaneta Nikolovska-Coleska, J. Chadwick Brenner, Keith G. Wolter, Guoping Wang, Cristina Martín de la Vega, Joshua A. Bauer, Monique Verhaegen
The RAS/BRAF/MEK/ERK mitogen-activated protein kinase (MAPK) pathway is emerging as a key modulator of melanoma initiation and progression. However, a variety of clinical studies indicate that inhibiting the MAPK pathway is insufficient per se to eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c4c60b75f19831beb1a6d18659d6f0
https://doi.org/10.1158/0008-5472.c.6495426
https://doi.org/10.1158/0008-5472.c.6495426
Autor:
María S. Soengas, Scott W. Lowe, Anthony W. Opipari, Philipp Steiner, Jenny L. Rush, Thomas P. Miller, Monique Verhaegen, Yolanda Fernández
Supplementary Information from Differential Regulation of Noxa in Normal Melanocytes and Melanoma Cells by Proteasome Inhibition: Therapeutic Implications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9eb42a360b013e62024458ed7b388d
https://doi.org/10.1158/0008-5472.22363728.v1
https://doi.org/10.1158/0008-5472.22363728.v1
Autor:
María S. Soengas, Shaomeng Wang, Carol R. Bradford, Thomas E. Carey, Matt Van Brocklin, James T. Elder, Rajan Nair, Audrey Bengtson, Zaneta Nikolovska-Coleska, J. Chadwick Brenner, Keith G. Wolter, Guoping Wang, Cristina Martín de la Vega, Joshua A. Bauer, Monique Verhaegen
Supplementary Materials, Methods and Figure Legends 1-5 from A Novel BH3 Mimetic Reveals a Mitogen-Activated Protein Kinase–Dependent Mechanism of Melanoma Cell Death Controlled by p53 and Reactive Oxygen Species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2272495c178f08c83ca6edf04e6072cd
https://doi.org/10.1158/0008-5472.22367100
https://doi.org/10.1158/0008-5472.22367100
Autor:
Eva Pérez-Guijarro, Panagiotis Karras, Metehan Cifdaloz, Raúl Martínez-Herranz, Estela Cañón, Osvaldo Graña, Celia Horcajada-Reales, Direna Alonso-Curbelo, Tonantzin G. Calvo, Gonzalo Gómez-López, Nicolas Bellora, Erica Riveiro-Falkenbach, Pablo L. Ortiz-Romero, José L. Rodríguez-Peralto, Lorena Maestre, Giovanna Roncador, Juan C. de Agustín Asensio, Colin R. Goding, Eduardo Eyras, Diego Megías, Raúl Méndez, María S. Soengas
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
Cytoplasmic polyadenylated transcripts have been poorly characterized, particularly in cancer. Here the authors identify a lineage-specific requirement of the cytoplasmic polyadenylation binding protein 4 (CPEB4) in malignant melanoma and show that i
Externí odkaz:
https://doaj.org/article/4fec995c232548e9812db54cfb254079