Zobrazeno 1 - 10
of 35
pro vyhledávání: '"María Pertusa"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Cold thermoreceptor neurons detect temperature drops with highly sensitive molecular machinery concentrated in their peripheral free nerve endings. The main molecular entity responsible for cold transduction in these neurons is the thermo-TRP channel
Externí odkaz:
https://doaj.org/article/310524fb54d24cf48268fd4e36833175
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Thermal Fluctuations Spectroscopy (TFS) in combination with novel optical-based instrumentation was used to study mechanical properties of cell-cultured neurites with a spatial resolution limited only by the light diffraction. The analysis of thermal
Externí odkaz:
https://doaj.org/article/91edc9439922493ba4521532aaa5ae4d
Autor:
Eva María Pertusa Ortega, Juan José Tarí Guilló, Jorge Pereira Moliner, José Francisco Molina Azorín, Mª Dolores López Gamero
Publikováno v:
Intangible Capital, Vol 9, Iss 1, Pp 199-224 (2013)
Purpose: Quality certification helps companies to improve efficiency and performance. The aim of this study is to analyze the differences between certified and non-certified hotels regarding the implementation of quality management practices, the per
Externí odkaz:
https://doaj.org/article/bee6c298cb914f10b2c9e2c602b94980
Publikováno v:
Intangible Capital, Vol 4, Iss 3, Pp 166-190 (2008)
The paper analyzes how the traditional variables that define a firm’s organizational structure (formalization, complexity, and centralization) influence knowledge performance (the degree to which a firm generates knowledge and uses it to reach a co
Externí odkaz:
https://doaj.org/article/5d46a98d8b184e7b98a239e4075f67c0
Autor:
Félix Viana, Patricio Orio, Kang Sik Park, Jorge Fernández-Trillo, Boris Lavanderos, María Pertusa, Ji Yeon Hwang, Claudio Moreno, Bastián Rivera, Rodolfo Madrid
Publikováno v:
J Neurosci
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
In mammals, environmental cold sensing conducted by peripheral cold thermoreceptor neurons mostly depends on TRPM8, an ion channel that has evolved to become the main molecular cold transducer. This TRP channel is activated by cold, cooling compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a30608e0aa60a7b8ec17e638df879f
http://hdl.handle.net/10261/267479
http://hdl.handle.net/10261/267479
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 12
International Journal of Molecular Sciences, Vol 21, Iss 4420, p 4420 (2020)
Volume 21
Issue 12
International Journal of Molecular Sciences, Vol 21, Iss 4420, p 4420 (2020)
TRPM8 is the main molecular entity responsible for cold sensing. This polymodal ion channel is activated by cold, cooling compounds such as menthol, voltage, and rises in osmolality. In corneal cold thermoreceptor neurons (CTNs), TRPM8 expression det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ce2441634f1d94561d72b7ca09a19c
Autor:
Rodolfo Madrid, María Pertusa
Publikováno v:
Temperature. 4:346-349
Exposure of body surface to temperature reductions evokes a wide variety of cold sensations, from comfortable cooling to intense pain depending on the intensity, speed and duration of the stimulus....
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::257ac23443e026b4279390bfa540863b
https://doi.org/10.1080/23328940.2017.1341968
https://doi.org/10.1080/23328940.2017.1341968
Autor:
Ricardo Piña, Pablo Rozas, Ashok B. Kulkarni, Rodolfo Madrid, Christian Gonzalez-Billault, María Pertusa, Andrew Cho, Pablo Lazcano, Elias Utreras, Anita Terse
Publikováno v:
Pain
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
We reported earlier that TNF-α, a proinflammatory cytokine implicated in many inflammatory disorders causing orofacial pain, increases the activity of Cdk5, a key kinase involved in brain development and function and recently found to be involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172fd9bee8bb523223d7d668794c78e4
https://doi.org/10.1097/j.pain.0000000000000527
https://doi.org/10.1097/j.pain.0000000000000527
Non-conventional Axonal Organelles Control TRPM8 Ion Channel Trafficking and Peripheral Cold Sensing
Autor:
María de los Ángeles Juricic, Carolina González, Víctor Hugo Cornejo, Andrés Couve, Matías Campos, Stéphanie Miserey-Lenkei, Rodolfo Madrid, Leslie Vargas-Saturno, María Pertusa
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2020, 30 (13), pp.4505-4517. ⟨10.1016/j.celrep.2020.03.017⟩
Cell Reports, Elsevier Inc, 2020, 30 (13), pp.4505-4517. ⟨10.1016/j.celrep.2020.03.017⟩
International audience; TRPM8 is the main ion channel responsible for cold transduction in the somatosensory system. Nerve terminal availability of TRPM8 determines cold sensitivity, but how axonal secretory organelles control channel delivery remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd156933d79060aa9aed2b7c38a7a161
https://doi.org/10.1016/j.celrep.2020.03.017
https://doi.org/10.1016/j.celrep.2020.03.017
Publikováno v:
The Journal of biological chemistry. 293(32)
In mammals, the main molecular entity involved in innocuous cold transduction is TRPM8. This polymodal ion channel is activated by cold, cooling compounds such as menthol and voltage. Despite its relevance, the molecular determinants involved in its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571452ac24daf111ff1a1082064832b2
https://pubmed.ncbi.nlm.nih.gov/29880642
https://pubmed.ncbi.nlm.nih.gov/29880642