Zobrazeno 1 - 10
of 114
pro vyhledávání: '"María Paz Ocaranza"'
Autor:
Jorge E. Jalil, Luigi Gabrielli, María Paz Ocaranza, Paul MacNab, Rodrigo Fernández, Bruno Grassi, Paulina Jofré, Hugo Verdejo, Monica Acevedo, Samuel Cordova, Luis Sanhueza, Douglas Greig
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4407 (2024)
This review examines the impact of obesity on the pathophysiology of heart failure with preserved ejection fraction (HFpEF) and focuses on novel mechanisms for HFpEF prevention using a glucagon-like peptide-1 receptor agonism (GLP-1 RA). Obesity can
Externí odkaz:
https://doaj.org/article/efe8ad8cc25f49fc8cefdf023d601dfd
Autor:
Felipe Contreras-Briceño, Sebastián Herrera, Julian Vega-Adauy, Manuel Salinas, María Paz Ocaranza, Jorge E. Jalil, Jorge Mandiola, Lorena García, Mario Chiong, Pablo F. Castro, Sergio Lavandero, Luigi Gabrielli
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Introduction: An increased risk of atrial fibrillation (AF) has been demonstrated in high-performance athletes. Soluble vascular adhesion molecule-1 (sVCAM-1), a biomarker involved in inflammation and cardiac remodeling, is associated with the develo
Externí odkaz:
https://doaj.org/article/a7f77ab658454e38a792bc7f5c527b4c
Autor:
Paulina Villar-Fincheira, Aaron J. Paredes, Tomás Hernández-Díaz, Ignacio Norambuena-Soto, Nicole Cancino-Arenas, Fernanda Sanhueza-Olivares, Felipe Contreras-Briceño, Jorge Mandiola, Nicole Bruneau, Lorena García, María Paz Ocaranza, Rodrigo Troncoso, Luigi Gabrielli, Mario Chiong
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Little is known about the effects of training load on exercise-induced plasma increase of interleukin-6 (IL-6) and soluble IL-6 receptor (sIL-6R) and their relationship with vascular remodeling. We sought to evaluate the role of sIL 6R as a regulator
Externí odkaz:
https://doaj.org/article/30591f36357147439c19e17f73b57cff
Autor:
Carolina Fernández, Natalia Torrealba, Francisco Altamirano, Valeria Garrido-Moreno, César Vásquez-Trincado, Raúl Flores-Vergara, Camila López-Crisosto, María Paz Ocaranza, Mario Chiong, Zully Pedrozo, Sergio Lavandero
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255452 (2021)
Cardiac hypertrophy is the result of responses to various physiological or pathological stimuli. Recently, we showed that polycystin-1 participates in cardiomyocyte hypertrophy elicited by pressure overload and mechanical stress. Interestingly, polyc
Externí odkaz:
https://doaj.org/article/282852eddbe64e25877af76197d62e17
Autor:
Felipe Contreras-Briceño, Julián Vega, Jorge Mandiola, María Paz Ocaranza, Sebastián Herrera, Manuel Salinas, Rodrigo Fernández, Jorge E. Jalil, Sergio Lavandero, Mario Chiong, Paz Godoy, Pablo F. Castro, Marta Sitges, Luigi Gabrielli
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 10, p 118 (2021)
This single-blind and cross-sectional study evaluated the role of Rho-kinase (ROCK) as a biomarker of the cardiovascular remodelling process assessed by echocardiography in competitive long-distance runners (LDRs) during the training period before a
Externí odkaz:
https://doaj.org/article/5ee13dd1905e454b8bc51ad28be736e3
Autor:
Sabrina Sepúlveda-Rivas, Matías S. Leal, Zully Pedrozo, Marcelo J. Kogan, María Paz Ocaranza, Javier O. Morales
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 822 (2021)
Ang-(1-9) peptide is a bioactive vasodilator peptide that prevents cardiomyocyte hypertrophy in vitro and in vivo as well as lowers blood pressure and pathological cardiovascular remodeling; however, it has a reduced half-life in circulation, requiri
Externí odkaz:
https://doaj.org/article/4d48c4ba122d4e159234a8b26ac613d3
Autor:
Samuel Martínez-Meza, Jorge Díaz, Alejandra Sandoval-Bórquez, Manuel Valenzuela-Valderrama, Natalia Díaz-Valdivia, Victoria Rojas-Celis, Pamela Contreras, Ricardo Huilcaman, María Paz Ocaranza, Mario Chiong, Lisette Leyton, Sergio Lavandero, Andrew F.G. Quest
Publikováno v:
Cancers, Vol 11, Iss 9, p 1299 (2019)
The renin−angiotensin receptor AT2R controls systemic blood pressure and is also suggested to modulate metastasis of cancer cells. However, in the latter case, the mechanisms involved downstream of AT2R remain to be defined. We recently described a
Externí odkaz:
https://doaj.org/article/beb7c52d7f4948ba902a78114449e950
Autor:
María Paz Ocaranza, Jorge E. Jalil
Publikováno v:
International Journal of Hypertension, Vol 2012 (2012)
Despite reduction in cardiovascular (CV) events and end-organ damage with the current pharmacologic strategies, CV disease remains the primary cause of death in the world. Pharmacological therapies based on the renin angiotensin system (RAS) blockade
Externí odkaz:
https://doaj.org/article/0b54ce7dd7c7412aba39d3c6756018a6
Autor:
Jorge E. Jalil, María Paz Ocaranza, Ulises Novoa, David Mondaca-Ruff, Italo Mora, Patricio Araos, Cristian Yañez
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 26:724-735
Background: Thiazides are one of the most common antihypertensive drugs used for hypertension treatment and hydrochlorothiazide (HCTZ) is the most frequently used diuretic for hypertension treatment. The Rho/Rho-kinase (ROCK) path plays a key functio
Autor:
María Paz Ocaranza, Jorge E. Jalil, Alejandra Lonis, Jackeline Moya, Luigi Gabrielli, Attilio Rigotti
Publikováno v:
Revista chilena de cardiología v.39 n.1 2020
SciELO Chile
CONICYT Chile
instacron:CONICYT
SciELO Chile
CONICYT Chile
instacron:CONICYT
Resumen: Introducción: Los ratones SR-B1 KO/ApoER6 1h/h que son alimentados con una dieta rica en grasas saturadas, desarrollan enfermedad coronaria aterosclerótica severa, complicaciones isquémicas e insuficiencia cardíaca, con alta mortalidad.