Zobrazeno 1 - 10
of 150
pro vyhledávání: '"María Otero"'
Autor:
Juan P. Rodrigo, Mario Sánchez-Canteli, María Otero-Rosales, Pablo Martínez-Camblor, Francisco Hermida-Prado, Juana M. García-Pedrero
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background Tumor mutational burden (TMB) has been demonstrated to predict the response to immune checkpoint inhibitors (ICIs) in various cancers. However, the role of TMB in head and neck squamous cell carcinoma (HNSCC) has not yet been spec
Externí odkaz:
https://doaj.org/article/4e57d01ea0994bee808b0294c5862597
Autor:
Lara Sofía Estévez Pérez, Begoña O. Alén, María Otero Alén, Saioa Domínguez Hormaetxe, Laureano Simón, Ángel Concha
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9567 (2024)
The early detection of tumors is one of the key factors in increasing overall survival in cancer patients. A wide range of cancers still do not have a system of early diagnosis; therefore, the development of new non-invasive tools in this line is ess
Externí odkaz:
https://doaj.org/article/9959e96295cd40e996f9e1c85efaa6e4
Autor:
Irene Montoro-Jiménez, Rocío Granda-Díaz, Sofía T. Menéndez, Llara Prieto-Fernández, María Otero-Rosales, Miguel Álvarez-González, Vanessa García-de-la-Fuente, Aida Rodríguez, Juan P. Rodrigo, Saúl Álvarez-Teijeiro, Juana M. García-Pedrero, Francisco Hermida-Prado
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2695 (2024)
The PIK3CA and SOX2 genes map at 3q26, a chromosomal region frequently amplified in head and neck cancers, which is associated with poor prognosis. This study explores the clinical significance of PIK3CA and SOX2 gene amplification in early tumorigen
Externí odkaz:
https://doaj.org/article/cb06395c30bb4d9c8614799e54754a49
Autor:
Llara Prieto-Fernández, Irene Montoro-Jiménez, Beatriz de Luxan-Delgado, María Otero-Rosales, Juan P. Rodrigo, Fernando Calvo, Juana M. García-Pedrero, Saúl Álvarez-Teijeiro
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 161, Iss , Pp 114502- (2023)
Head and neck cancers (HNC) are a diverse group of aggressive malignancies with high morbidity and mortality, leading to almost half-million deaths annually worldwide. A better understanding of the molecular processes governing tumor formation and pr
Externí odkaz:
https://doaj.org/article/dc13de297d7046a09ee0e8023dd05c77
Autor:
Manuel Lozano, Adina Iftimi, Alvaro Briz-Redon, Juanjo Peiró, Lara Manyes, María Otero, Mayte Ballester, M. Dolores de las Marinas, Juan Carlos Catalá, José de Andrés, Carolina Romero
Publikováno v:
Infectious Medicine, Vol 1, Iss 2, Pp 81-87 (2022)
Background: The heterogeneity of patients with COVID-19 may explain the wide variation of mortality rate due to the population characteristics, presence of comorbidities and clinical manifestations. Methods: In this study, we analyzed 5342 patients'
Externí odkaz:
https://doaj.org/article/ec48b3b2346d4cc891a2a27be95c4f0c
Autor:
Gráinne Cousins, Kathleen E Bennett, Paul Corcoran, Ella Arensman, Eamon Keenan, Suzi Lyons, Louise Durand, Aoife O’Kane, Julie Tierney, Richard Maguire, Siobhán Stokes, Deirdre O’Reilly, María Otero Vázquez, Yvonne Kavanagh
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Introduction There is an increasing concern about the misuse of prescription drugs. Misuse refers to the intentional repurposing of prescribed drugs and/or the use of illicitly sourced prescription drugs, which may be counterfeit or contaminated. Dru
Externí odkaz:
https://doaj.org/article/a0de4bbbac4342309cdbdb5793608802
Autor:
Llara Prieto-Fernández, Sofía T. Menéndez, María Otero-Rosales, Irene Montoro-Jiménez, Francisco Hermida-Prado, Juana M. García-Pedrero, Saúl Álvarez-Teijeiro
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Annexins are an extensive superfamily of structurally related calcium- and phospholipid-binding proteins, largely conserved and widely distributed among species. Twelve human annexins have been identified, referred to as Annexin A1-13 (A12 remains as
Externí odkaz:
https://doaj.org/article/b2b17d4e21184b95a6db49572eefbb9d
Autor:
Juan M. Vázquez-Lago, Rodrigo A. Montes-Villalba, Olalla Vázquez-Cancela, María Otero-Santiago, Ana López-Durán, Adolfo Figueiras
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 558 (2023)
Antibiotic resistance is a significant public health concern, with numerous studies linking antibiotic consumption to the development of resistance. As medical students will play a pivotal role in prescribing antibiotics, this research aimed to ident
Externí odkaz:
https://doaj.org/article/648b002336614bb79be9d039500f11a6
Autor:
Begoña O. Alen, Lara Sofía Estévez-Pérez, María Otero Alén, Saioa Domínguez Hormaetxe, Laureano Simón, Ángel Concha
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3578 (2023)
Tumor-derived extracellular vesicles (TD-EVs) have active roles as cancer hallmark enablers. EVs RNA of epithelial and stromal cells carry information that facilitates the communication processes that contribute to oncological progression, so the obj
Externí odkaz:
https://doaj.org/article/fb29ed0a587b4c268b8a06bbce0bf903
Autor:
Mario Sánchez-Canteli, Luis Juesas, Irati Garmendia, María Otero-Rosales, Alfonso Calvo, Monica Alvarez-Fernández, Aurora Astudillo, Luis M. Montuenga, Juana M. García-Pedrero, Juan P. Rodrigo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11559 (2022)
Activation of WNT/β-catenin signaling has been associated with a non-T-cell-inflamed tumor microenvironment (TME) in several cancers. The aim of this work was to investigate the relationship between β-catenin signaling and TME inflammation in head
Externí odkaz:
https://doaj.org/article/326918e46c26474287c7790a59edd7f9