Zobrazeno 1 - 8 of 8 pro vyhledávání: '"María Mercedes De Zan"'
1
A multiparametric model for the industrialization of co-precipitation synthesis of nano-commodities
Autor: Lilian Celeste Alarcon Segovia, Carlos Acha, Jorge Ivan Daza Agudelo, Ignacio Rintoul, Romina Julieta Glisoni, María Mercedes De Zan
Publikováno v: Nanotechnology. 31(18)
Magnetite superparamagnetic nanoparticles (MNP) are becoming one of the firsts nanocommodity products. MNP find a number of applications and they are been produced at relatively large scale. The co-precipitation method presents many technical and eco
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953bb075e6684fa4d0bf333a0ec36a75
https://pubmed.ncbi.nlm.nih.gov/31995532
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2
New Amphiphilic Amino Acid Derivatives for Efficient DNA Transfection in Vitro
Autor: Lucía Carolina Peña, Sebastián Antuña, Diana María Müller, María Mercedes de Zan, Antonella Giorello, María F. Argarañá, Carolina Veaute, Claudio Prieto
Publikováno v: Advances in Chemical Engineering and Science. :191-205
Nucleic acids-based therapies have recently developed as next-generation agents for treating and preventing viral infection, cancer, and genetic disorders, but their use is still limited due to its relatively poor delivery into targeted cells. We des
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a829bb6d632263d407ca893b7015aaf
https://doi.org/10.4236/aces.2017.72014
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3
Optimized high performance liquid chromatography–ultraviolet detection method using core-shell particles for the therapeutic monitoring of methotrexate
Autor: María Mercedes de Zan, Milagros Montemurro, Juan C. Robles
Publikováno v: Journal of Pharmaceutical Analysis, Vol 6, Iss 2, Pp 103-111 (2016)
Journal of Pharmaceutical Analysis
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Methotrexate (MTX) is an antineoplastic drug, and due to its high toxicity, the therapeutic drug monitoring is strictly conducted in the clinical practice. The chemometric optimization and validation of a high performance liquid chromatography (HPLC)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908be6d943fd5280015cb90b9dce1c11
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4
Activity-Structure Study on the Peptide Fraction of AG2: a Potent In Vitro Transfection Agent
Autor: Claudio Prieto, Antonella Giorello, Sebastián Antuña, Diana María Müller, Lucía Daniela Grippo, María Mercedes de Zan, Juan Manuel Rudi, Carolina Veaute
Publikováno v: Applied biochemistry and biotechnology. 189(2)
Gemini-based amphiphiles are candidates for biomedical applications. In fact, most of thegemini compounds described in the literature have been prepared to be used as new syntheticvectors in gene transfection. Our group carried out an activity-struct
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2988b9ef1a752f60bd70f64d85f35dcc
https://pubmed.ncbi.nlm.nih.gov/31093907
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5
Multiple responses optimization in the development of a headspace gas chromatography method for the determination of residual solvents in pharmaceuticals
Autor: María S. Cámara, Carla Mariela Teglia, Milagros Montemurro, María Mercedes de Zan
Publikováno v: Journal of Pharmaceutical Analysis, Vol 5, Iss 5, Pp 296-306 (2015)
Journal of Pharmaceutical Analysis
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
An efficient generic static headspace gas chromatography (HSGC) method was developed, optimized and validated for the routine determination of several residual solvents (RS) in drug substance, using a strategy with two sets of calibration. Dimethylsu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b185b7c4d9c67c18fb826be23b3e4c50
https://www.sciencedirect.com/science/article/pii/S2095177915000325
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6
Experimental design and multiple response optimization: Using the desirability function in analytical methods development
Autor: María Mercedes de Zan, Héctor C. Goicoechea, María S. Cámara, Luciana Vera Candioti
A review about the application of response surface methodology (RSM) when several responses have to be simultaneously optimized in the field of analytical methods development is presented. Several critical issues like response transformation, multipl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5cbe2b2ab112f107706c4ac808d89f
https://www.sciencedirect.com/science/article/pii/S0039914014000459
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7
Using Chemometrics to Improve the Performance of High Resolution Liquid Chromatography. Application to the Determination of Substances of Biological Interest in Samples of Complex Composition
Autor: María Mercedes, De Zan
Publikováno v: Biblioteca Virtual (UNL)
Universidad Nacional del Litoral
instacron:UNL
Fil: María Mercedes, De Zan. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas; Argentina. En esta tesis se utilizaron diversas herramientas quimiométricas para alcanzar mejoras significativas en el rendimiento de la
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::f9d12f025c9fcb301780486631930371
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