Zobrazeno 1 - 8
of 8
pro vyhledávání: '"María Linarejos Vera-Pedrosa"'
Autor:
Pablo Gómez-del Arco, Joan Isern, Daniel Jimenez-Carretero, Dolores López-Maderuelo, Rebeca Piñeiro-Sabarís, Fadoua El Abdellaoui-Soussi, Carlos Torroja, María Linarejos Vera-Pedrosa, Mercedes Grima-Terrén, Alberto Benguria, Ana Simón-Chica, Antonio Queiro-Palou, Ana Dopazo, Fátima Sánchez-Cabo, José Jalife, José Luis de la Pompa, David Filgueiras-Rama, Pura Muñoz-Cánoves, Juan Miguel Redondo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Extensive genetic studies have elucidated cardiomyocyte differentiation and associated gene networks using single-cell RNA-seq, yet the intricate transcriptional mechanisms governing cardiac conduction system (CCS) development and working ca
Externí odkaz:
https://doaj.org/article/6e6e018aa0f54c20af7b9385311cf831
Autor:
Aurora Gómez-Vecino, Roberto Corchado-Cobos, Adrián Blanco-Gómez, Natalia García-Sancha, Sonia Castillo-Lluva, Ana Martín-García, Marina Mendiburu-Eliçabe, Carlos Prieto, Sara Ruiz-Pinto, Guillermo Pita, Alejandro Velasco-Ruiz, Carmen Patino-Alonso, Purificación Galindo-Villardón, María Linarejos Vera-Pedrosa, José Jalife, Jian-Hua Mao, Guillermo Macías de Plasencia, Andrés Castellanos-Martín, María del Mar Sáez-Freire, Susana Fraile-Martín, Telmo Rodrigues-Teixeira, Carmen García-Macías, Julie Milena Galvis-Jiménez, Asunción García-Sánchez, María Isidoro-García, Manuel Fuentes, María Begoña García-Cenador, Francisco Javier García-Criado, Juan Luis García-Hernández, María Ángeles Hernández-García, Juan Jesús Cruz-Hernández, César Augusto Rodríguez-Sánchez, Alejandro Martín García-Sancho, Estefanía Pérez-López, Antonio Pérez-Martínez, Federico Gutiérrez-Larraya, Antonio J. Cartón, José Ángel García-Sáenz, Ana Patiño-García, Miguel Martín, Teresa Alonso-Gordoa, Christof Vulsteke, Lieselot Croes, Sigrid Hatse, Thomas Van Brussel, Diether Lambrechts, Hans Wildiers, Hang Chang, Marina Holgado-Madruga, Anna González-Neira, Pedro L. Sánchez, Jesús Pérez Losada
Publikováno v:
Cells, Vol 12, Iss 15, p 1956 (2023)
Cardiotoxicity due to anthracyclines (CDA) affects cancer patients, but we cannot predict who may suffer from this complication. CDA is a complex trait with a polygenic component that is mainly unidentified. We propose that levels of intermediate mol
Externí odkaz:
https://doaj.org/article/30117a66c9fb4e32901af4d0a0a24d13
Autor:
Ana Isabel Moreno-Manuel, Lilian K Gutiérrez, María Linarejos Vera-Pedrosa, Francisco Miguel Cruz, Francisco José Bermúdez-Jiménez, Isabel Martínez-Carrascoso, Patricia Sánchez-Pérez, Álvaro Macías, José Jalife
Publikováno v:
Cardiovascular Research
Andersen Tawil Syndrome (ATS) is a rare inheritable disease associated with loss-of-function mutations in KCNJ2, the gene coding the strong inward rectifier potassium channel Kir2.1, which forms an essential membrane protein controlling cardiac excit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344244bb03686a75fc68fe7f6a618cb0
https://academic.oup.com/cardiovascres/advance-article-pdf/doi/10.1093/cvr/cvac118/45212643/cvac118.pdf
https://academic.oup.com/cardiovascres/advance-article-pdf/doi/10.1093/cvr/cvac118/45212643/cvac118.pdf
Autor:
Álvaro Macías, Andrés González-Guerra, Ana I. Moreno-Manuel, Francisco M. Cruz, Lilian K. Gutiérrez, Nieves García-Quintáns, Marta Roche-Molina, Francisco Bermúdez-Jiménez, Vicente Andrés, María Linarejos Vera-Pedrosa, Isabel Martínez-Carrascoso, Juan A. Bernal, José Jalife
We thank C. Galán-Arriola (from CNIC) for help in the graphical illustration of the manuscript; M. Fernández-Tenorio (from the University of Bern) for valuable guidance in the experimental details of calcium dynamics in permeabilized cells; and H.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6096e8ff26ee527e2006ee3c0a5665a8
https://hdl.handle.net/20.500.12105/15257
https://hdl.handle.net/20.500.12105/15257
Autor:
Nieves García-Quintáns, Marta Roche-Molina, Isabel Martínez-Carrascoso, Alvaro Macias, Ana I. Moreno-Manuel, Lilian K. Gutiérrez, Andrés González-Guerra, José Jalife, Vicente Andrés, Francisco Bermúdez-Jiménez, Francisco Cruz, Juan A. Bernal, María Linarejos Vera-Pedrosa
Publikováno v:
Circulation Research. 129
Background: Andersen-Tawil syndrome type 1 (ATS1), caused by trafficking deficient mutations in the gene KCNJ2 coding the inward rectifier K + channel Kir2.1, is associated with life-threatening arrhythmias, which in some patients resemble catecholam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c86aa932511bdbc05766b3b2d18001c
https://doi.org/10.1161/res.129.suppl_1.p356
https://doi.org/10.1161/res.129.suppl_1.p356
Autor:
Francisco Bermúdez-Jiménez, Marta Roche-Molina, Lilian K. Gutiérrez, Isabel Martínez-Carrascoso, José Jalife, Nieves García-Quintáns, Alvaro Macias, Juan A. Bernal, Andrés González-Guerra, Vicente Andrés, María Linarejos Vera-Pedrosa, Ana I. Moreno-Manuel, Francisco Cruz
Andersen-Tawil Syndrome (ATS) is associated with life threatening arrhythmias of unknown mechanism. We report on a mouse model carrying the trafficking-deficient mutant Kir2.1Δ314-315. The mouse recapitulates the electrophysiological phenotype of ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5421fcc83fab0a28d1b5d72cc4656855
https://doi.org/10.1101/2021.06.17.448833
https://doi.org/10.1101/2021.06.17.448833
Autor:
Juan A. Bernal, Lilian K. Gutiérrez, Nieves García-Quintáns, Francisco Bermúdez-Jiménez, Marta Roche-Molina, Alvaro Macias, Ana I. Moreno-Manuel, María Linarejos Vera-Pedrosa, Francisco Cruz, Isabel Martínez-Carrascoso, Andrés González-Guerra, José Jalife
Publikováno v:
Heart Rhythm. 18:S35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c000ee0765721c2ecbf5a810a82b98a3
https://doi.org/10.1016/j.hrthm.2021.06.103
https://doi.org/10.1016/j.hrthm.2021.06.103
Autor:
María Linarejos Vera-Pedrosa, Ana I. Moreno-Manuel, Luis Tercedor, Miguel A. Alvarez, Francisco Bermúdez, Lilian Gutiérrez Espinosa de los Monteros, Juan Jiménez Jáimez
Publikováno v:
Journal of the American College of Cardiology. 75:469
Short QT Syndrome (SQTS) is a very rare cardiac channelopathy that leads to an abbreviated QTc interval and sudden cardiac death (SCD). It is a genetically heterogeneous entity, with only 25 % of cases identified as having a pathogenic mutation in ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f8d9bf63e69129987cfe68e8c98110
https://doi.org/10.1016/s0735-1097(20)31096-2
https://doi.org/10.1016/s0735-1097(20)31096-2