Zobrazeno 1 - 9
of 9
pro vyhledávání: '"María Linarejos Vera Pedrosa"'
Autor:
Pablo Gómez-del Arco, Joan Isern, Daniel Jimenez-Carretero, Dolores López-Maderuelo, Rebeca Piñeiro-Sabarís, Fadoua El Abdellaoui-Soussi, Carlos Torroja, María Linarejos Vera-Pedrosa, Mercedes Grima-Terrén, Alberto Benguria, Ana Simón-Chica, Antonio Queiro-Palou, Ana Dopazo, Fátima Sánchez-Cabo, José Jalife, José Luis de la Pompa, David Filgueiras-Rama, Pura Muñoz-Cánoves, Juan Miguel Redondo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Extensive genetic studies have elucidated cardiomyocyte differentiation and associated gene networks using single-cell RNA-seq, yet the intricate transcriptional mechanisms governing cardiac conduction system (CCS) development and working ca
Externí odkaz:
https://doaj.org/article/6e6e018aa0f54c20af7b9385311cf831
Autor:
Aurora Gómez-Vecino, Roberto Corchado-Cobos, Adrián Blanco-Gómez, Natalia García-Sancha, Sonia Castillo-Lluva, Ana Martín-García, Marina Mendiburu-Eliçabe, Carlos Prieto, Sara Ruiz-Pinto, Guillermo Pita, Alejandro Velasco-Ruiz, Carmen Patino-Alonso, Purificación Galindo-Villardón, María Linarejos Vera-Pedrosa, José Jalife, Jian-Hua Mao, Guillermo Macías de Plasencia, Andrés Castellanos-Martín, María del Mar Sáez-Freire, Susana Fraile-Martín, Telmo Rodrigues-Teixeira, Carmen García-Macías, Julie Milena Galvis-Jiménez, Asunción García-Sánchez, María Isidoro-García, Manuel Fuentes, María Begoña García-Cenador, Francisco Javier García-Criado, Juan Luis García-Hernández, María Ángeles Hernández-García, Juan Jesús Cruz-Hernández, César Augusto Rodríguez-Sánchez, Alejandro Martín García-Sancho, Estefanía Pérez-López, Antonio Pérez-Martínez, Federico Gutiérrez-Larraya, Antonio J. Cartón, José Ángel García-Sáenz, Ana Patiño-García, Miguel Martín, Teresa Alonso-Gordoa, Christof Vulsteke, Lieselot Croes, Sigrid Hatse, Thomas Van Brussel, Diether Lambrechts, Hans Wildiers, Hang Chang, Marina Holgado-Madruga, Anna González-Neira, Pedro L. Sánchez, Jesús Pérez Losada
Publikováno v:
Cells, Vol 12, Iss 15, p 1956 (2023)
Cardiotoxicity due to anthracyclines (CDA) affects cancer patients, but we cannot predict who may suffer from this complication. CDA is a complex trait with a polygenic component that is mainly unidentified. We propose that levels of intermediate mol
Externí odkaz:
https://doaj.org/article/30117a66c9fb4e32901af4d0a0a24d13
Autor:
Ana Isabel Moreno-Manuel, Lilian K Gutiérrez, María Linarejos Vera-Pedrosa, Francisco Miguel Cruz, Francisco José Bermúdez-Jiménez, Isabel Martínez-Carrascoso, Patricia Sánchez-Pérez, Álvaro Macías, José Jalife
Publikováno v:
Cardiovascular Research
Andersen Tawil Syndrome (ATS) is a rare inheritable disease associated with loss-of-function mutations in KCNJ2, the gene coding the strong inward rectifier potassium channel Kir2.1, which forms an essential membrane protein controlling cardiac excit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344244bb03686a75fc68fe7f6a618cb0
https://academic.oup.com/cardiovascres/advance-article-pdf/doi/10.1093/cvr/cvac118/45212643/cvac118.pdf
https://academic.oup.com/cardiovascres/advance-article-pdf/doi/10.1093/cvr/cvac118/45212643/cvac118.pdf
Autor:
Álvaro Macías, Andrés González-Guerra, Ana I. Moreno-Manuel, Francisco M. Cruz, Lilian K. Gutiérrez, Nieves García-Quintáns, Marta Roche-Molina, Francisco Bermúdez-Jiménez, Vicente Andrés, María Linarejos Vera-Pedrosa, Isabel Martínez-Carrascoso, Juan A. Bernal, José Jalife
We thank C. Galán-Arriola (from CNIC) for help in the graphical illustration of the manuscript; M. Fernández-Tenorio (from the University of Bern) for valuable guidance in the experimental details of calcium dynamics in permeabilized cells; and H.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6096e8ff26ee527e2006ee3c0a5665a8
https://hdl.handle.net/20.500.12105/15257
https://hdl.handle.net/20.500.12105/15257
Autor:
Nieves García-Quintáns, Marta Roche-Molina, Isabel Martínez-Carrascoso, Alvaro Macias, Ana I. Moreno-Manuel, Lilian K. Gutiérrez, Andrés González-Guerra, José Jalife, Vicente Andrés, Francisco Bermúdez-Jiménez, Francisco Cruz, Juan A. Bernal, María Linarejos Vera-Pedrosa
Publikováno v:
Circulation Research. 129
Background: Andersen-Tawil syndrome type 1 (ATS1), caused by trafficking deficient mutations in the gene KCNJ2 coding the inward rectifier K + channel Kir2.1, is associated with life-threatening arrhythmias, which in some patients resemble catecholam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c86aa932511bdbc05766b3b2d18001c
https://doi.org/10.1161/res.129.suppl_1.p356
https://doi.org/10.1161/res.129.suppl_1.p356
Autor:
Francisco Bermúdez-Jiménez, Marta Roche-Molina, Lilian K. Gutiérrez, Isabel Martínez-Carrascoso, José Jalife, Nieves García-Quintáns, Alvaro Macias, Juan A. Bernal, Andrés González-Guerra, Vicente Andrés, María Linarejos Vera-Pedrosa, Ana I. Moreno-Manuel, Francisco Cruz
Andersen-Tawil Syndrome (ATS) is associated with life threatening arrhythmias of unknown mechanism. We report on a mouse model carrying the trafficking-deficient mutant Kir2.1Δ314-315. The mouse recapitulates the electrophysiological phenotype of ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5421fcc83fab0a28d1b5d72cc4656855
https://doi.org/10.1101/2021.06.17.448833
https://doi.org/10.1101/2021.06.17.448833
Autor:
Juan A. Bernal, Lilian K. Gutiérrez, Nieves García-Quintáns, Francisco Bermúdez-Jiménez, Marta Roche-Molina, Alvaro Macias, Ana I. Moreno-Manuel, María Linarejos Vera-Pedrosa, Francisco Cruz, Isabel Martínez-Carrascoso, Andrés González-Guerra, José Jalife
Publikováno v:
Heart Rhythm. 18:S35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c000ee0765721c2ecbf5a810a82b98a3
https://doi.org/10.1016/j.hrthm.2021.06.103
https://doi.org/10.1016/j.hrthm.2021.06.103
Autor:
Francisco Miguel Cruz Uréndez, Juan A. Bernal, Ana Isabel Moreno Manuel, Isabel Martínez Carrascoso, Alvaro Macias, María Linarejos Vera Pedrosa, José Jalife, Francisco José Bermúdez Jiménez, Lilian Karina Gutiérrez Espinosa de los Monteros
Publikováno v:
Heart Rhythm. 18:S371
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b06911d8baa059347f67ebb5d3e1529
https://doi.org/10.1016/j.hrthm.2021.06.921
https://doi.org/10.1016/j.hrthm.2021.06.921
Autor:
María Linarejos Vera-Pedrosa, Ana I. Moreno-Manuel, Luis Tercedor, Miguel A. Alvarez, Francisco Bermúdez, Lilian Gutiérrez Espinosa de los Monteros, Juan Jiménez Jáimez
Publikováno v:
Journal of the American College of Cardiology. 75:469
Short QT Syndrome (SQTS) is a very rare cardiac channelopathy that leads to an abbreviated QTc interval and sudden cardiac death (SCD). It is a genetically heterogeneous entity, with only 25 % of cases identified as having a pathogenic mutation in ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f8d9bf63e69129987cfe68e8c98110
https://doi.org/10.1016/s0735-1097(20)31096-2
https://doi.org/10.1016/s0735-1097(20)31096-2