Codon Usage Optimization in the Prokaryotic Tree of Life: How Synonymous Codons Are Differentially Selected in Sequence Domains with Different Expression Levels and Degrees of Conservation

Autor: José Luis López, Mauricio Javier Lozano, María Laura Fabre, Antonio Lagares

Publikováno v: mBio, Vol 11, Iss 4 (2020)

ABSTRACT Prokaryote genomes exhibit a wide range of GC contents and codon usages, both resulting from an interaction between mutational bias and natural selection. In order to investigate the basis underlying specific codon changes, we performed a co

Externí odkaz: https://doaj.org/article/82b58a7952f3483bbcd8fc8766553527

Genomic analysis of an Argentinean isolate of Spodoptera frugiperda granulovirus reveals that various baculoviruses code for Lef-7 proteins with three F-box domains.

Autor: María Leticia Ferrelli, Matías Luis Pidre, Pablo Daniel Ghiringhelli, Sofía Torres, María Laura Fabre, Tomás Masson, Maia Tatiana Cédola, Alicia Sciocco-Cap, Víctor Romanowski

Publikováno v: PLoS ONE, Vol 13, Iss 8, p e0202598 (2018)

A new isolate of the Spodoptera frugiperda granulovirus, SfGV ARG, was completely sequenced and analyzed. The SfGV ARG genome is 139,812 bp long and encodes 151 putative open reading frames. Of these ORFs, 56 were found in betabaculoviruses, 19 of wh

Externí odkaz: https://doaj.org/article/f7044492cf7a47059f6094580efb0125

HOTAIR Modulated Pathways in Early-Stage Breast Cancer Progression

Autor: Hyunsuk Kil, Pradeep Tatineni, María Laura Fabre, Martín Carlos Abba, Jaeho Lee, C. Marcelo Aldaz

Publikováno v: Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)

The long-non-coding HOX transcript antisense intergenic RNA (HOTAIR) was identified as significantly upregulated in breast ductal carcinoma in situ (DCIS). The aim of this study was to characterize the phenotypic effects and signaling pathways modula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b26bfc4c9148fe27bc4473cc724115
http://europepmc.org/articles/PMC8637884

Genomic diversity in a population of Spodoptera frugiperda nucleopolyhedrovirus

Autor: José María Niz, Víctor Romanowski, Marcelo Facundo Berretta, María Leticia Ferrelli, Matías Luis Pidre, María Laura Fabre, Tomás Masson

Publikováno v: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 90

Spodoptera frugiperda multiple nucleopolyhedrovirus (SfMNPV) represents a strong candidate to develop environmental-friendly pesticides against the fall armyworm (Spodoptera frugiperda), a widespread pest that poses a severe threat to different crops

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3a0cb81acd6431064d981dcf835766
https://pubmed.ncbi.nlm.nih.gov/33540087

Codon Usage Heterogeneity in the Multipartite Prokaryote Genome. Selection-Based Coding Bias Associated with Gene Location, Expression Level, and Ancestry

Autor: Walter Omar Draghi, José Luis López, Anke Becker, Andreas Schlüter, M. F. Del Papa, Mauricio Javier Lozano, Mariano Pistorio, María Laura Fabre, Daniel Wibberg, Jochen Blom, Alfred Pühler, Antonio Lagares, Alexander Goesmann

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
mBio
mBio, Vol 10, Iss 3, p e00505-19 (2019)
mBio, Vol 10, Iss 3 (2019)

Prokaryotes represent an ancestral lineage in the tree of life and constitute optimal resources for investigating the evolution of genomes in unicellular organisms. Many bacterial species possess multipartite genomes offering opportunities to study f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac020d883ff2ed0ff1c3e8cd88f4ac87
https://doi.org/10.1128/mbio.00505-19