Zobrazeno 1 - 10
of 25
pro vyhledávání: '"María Julia Ferronato"'
Autor:
Marilina Mascaró, Exequiel G. Alonso, Karen Schweitzer, Martín E. Rabassa, Jessica A. Carballido, Agustina Ibarra, Eliana N. Alonso, Vicente Bermúdez, Lucía Fernández Chavez, Georgina P. Coló, María Julia Ferronato, Pamela Pichel, Sergio Recio, Valentina Clemente, Maria Eugenia Fermento, María Marta Facchinetti, Alejandro C. Curino
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 2077 (2022)
Head and neck squamous cell carcinoma (HNSCC) is a remarkably heterogeneous disease with around 50% mortality, a fact that has prompted researchers to try new approaches to improve patient survival. Hemoxygenase-1 (HO-1) is the rate-limiting step for
Externí odkaz:
https://doaj.org/article/8b9ae97a653e4e21957ed079db67e2a1
Vitamin D analogues exhibit antineoplastic activity in breast cancer patient-derived xenograft cells
Autor:
Giuliana Paolillo, Mercedes Nadal Serrano, Marilina Mascaró, Alejandro Carlos Curino, Cristian Vitale, Yagamare Fall, Enrique Javier Arenas Lahuerta, Alex Martinez-Sabadell Aliguer, Hugo Santalla, Maria Marta Facchinetti, Cristina Bernadó Morales, Joaquín Arribas, María Julia Ferronato
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Despite advances in breast cancer (BC) treatment, its mortality remains high due to intrinsic or acquired resistance to therapy. Several ongoing efforts are being made to develop novel drugs to treat this pathology with the aim to overcome resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13a88ffc6564418f180f19d19b9b0716
https://www.sciencedirect.com/science/article/abs/pii/S0960076020302600
https://www.sciencedirect.com/science/article/abs/pii/S0960076020302600
Autor:
Alejandro Carlos Curino, Yagamare Fall, Mario Alfredo Quevedo, Cristian Vitale, Sergio R. Ribone, Maria Marta Facchinetti, María Julia Ferronato
The vitamin D receptor (VDR) constitutes a promising therapeutic target for the treatment of cancer. Unfortunately, its natural agonist calcitriol does not have clinical utility due to its potential to induce hypercalcemic effects at the concentratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dee002db523e09d771d4bde51e8a7de
https://linkinghub.elsevier.com/retrieve/pii/S0960076019307241
https://linkinghub.elsevier.com/retrieve/pii/S0960076019307241
Autor:
María Julia Ferronato, Mario Alfredo Quevedo, Alejandro Carlos Curino, Eliana Noelia Alonso, Santiago Armando Stabile, Evangelina Mascaró, Gabriel Radivoy, Maria Marta Facchinetti, Silvina Mariela Grioli, Cristian Vitale
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 17(3)
Background:1α,25-dihydroxy vitamin D3 (calcitriol) shows potent growth-inhibitory properties on different cancer cell lines, but its hypercalcemic effects have severely hampered its therapeutic application. Therefore, it is important to develop synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505b0d91a6f4320d41be472d9dbc9252
https://pubmed.ncbi.nlm.nih.gov/32819231
https://pubmed.ncbi.nlm.nih.gov/32819231
Autor:
Georgina Pamela Coló, Marilina Mascaró, Maria Marta Facchinetti, Martín Carlos Abba, Norberto Ariel Gandini, María Eugenia Fermento, María Julia Ferronato, Eliana Noelia Alonso, Julián Arévalo, Myriam Nuñez, Pamela Pichel, Alejandro Carlos Curino, Josefina Alejandra Guevara
Publikováno v:
Antioxidants & Redox Signaling. 30
Aims:Heme oxygenase-1 (HO-1) is an enzyme involved in cellular responses to oxidative stress and has alsobeen shown to regulate processes related to cancer progression. In this regard, HO-1 has been shown to displaya dual effect with either antitumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d79e1ed0f653b56423852754b5f6278
https://doi.org/10.1089/ars.2018.7554
https://doi.org/10.1089/ars.2018.7554
Autor:
Yagamare Fall, Diego Javier Obiol, Generosa Gómez, Eliana Noelia Alonso, Maria Marta Facchinetti, Mario Alfredo Quevedo, María Julia Ferronato, Andrea Martínez, Silvina Mariela Grioli, Alejandro Carlos Curino
The active form of vitamin D3, calcitriol, is a potent antiproliferative compound. However, when effective antitumor doses of calcitriol are used, hypercalcemic effects are observed, thus blocking its therapeutic application. To overcome this problem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0125fb5e0309b464d55547d1a0972b62
Wiley Online Library
Wiley Online Library
Antitumoral and antimetastatic activity of Maitake D-Fraction in triple-negative breast cancer cells
Autor:
María Julia Ferronato, Alejandro López Romero, Josefina Alejandra Guevara, Norberto Ariel Gandini, Maria Marta Facchinetti, María Eugenia Fermento, Alejandro Carlos Curino, Eliana Noelia Alonso
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Oncotarget
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Oncotarget
Triple-negative breast cancer (TNBC) is associated with poor prognosis, high local recurrence rate and high rate of metastasis compared with other breast cancer subtypes. In addition, TNBC lacks a targeted therapy. This scenario highlights the need f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdece524e05e26008b0e310f5470e6ad
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=25174&path[]=78890
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=25174&path[]=78890
Autor:
Diego Javier Obiol, Marilina Mascaró, Silvina Mariela Grioli, Yagamare Fall, Maria Marta Facchinetti, Marcos L. Rivadulla, Mario Alfredo Quevedo, Eliana Noelia Alonso, Generosa Gómez, María Julia Ferronato, Andrea Martínez, Josefina Alejandra Guevara, Alejandro Carlos Curino
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Calcitriol analogs have shown promising potential as compounds to be used in cancer chemotherapy. This report presents the synthesis of a novel vitamin D3 derivative with an amide and a carboxyl group in its side chain, called ML-344. In addition, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c97675fbfa6485a43daa71c6d7d2462
https://pubmed.ncbi.nlm.nih.gov/30125657
https://pubmed.ncbi.nlm.nih.gov/30125657
Autor:
Alejandro Carlos Curino, Norberto Ariel Gandini, Maria Marta Facchinetti, Yagamare Fall, Marcos L. Rivadulla, Generosa Gómez, Alejandro López Romero, María Eugenia Fermento, María Julia Ferronato, Débora Gisele Salomón, Manuel Pérez, Xenxo Pérez-García
Publikováno v:
Archiv der Pharmazie. 348:315-329
The active form of vitamin D3, 1α,25(OH)2D3, plays a major role in maintaining calcium/phosphate homeostasis. In addition, it is a potent antiproliferative and pro-differentiating agent. Unfortunately, it usually causes hypercalcemia in vivo when ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4870222a27f2e501ec038bf7df0be06
https://doi.org/10.1002/ardp.201400448
https://doi.org/10.1002/ardp.201400448
Autor:
Evangelina Mascaró, Alejandro Carlos Curino, Norberto Ariel Gandini, Eliana Noelia Alonso, Cristian Vitale, María Julia Ferronato, Maria Marta Facchinetti, Yagamare Fall, María Eugenia Fermento, Débora Gisele Salomón, Mario Alfredo Quevedo
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 178
Glioblastoma multiforme (GBM) is the worst and most common brain tumor, characterized by high proliferation and invasion rates. The current standard treatment is mainly based on chemoradiotherapy and this approach has slightly improved patient surviv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f0dab7dbfe3d7475ae9af1d86f93b8
https://pubmed.ncbi.nlm.nih.gov/29102624
https://pubmed.ncbi.nlm.nih.gov/29102624