Zobrazeno 1 - 10
of 15
pro vyhledávání: '"María Julia Castro"'
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Nematode parasitosis causes significant mortality and morbidity in humans and considerable losses in livestock and domestic animals. The acquisition of resistance to current anthelmintic drugs has prompted the search for new compounds for which the f
Externí odkaz:
https://doaj.org/article/30f7c496b5494307acb834a3337d212c
Autor:
María Alejandra Sequeira, Marcos J. Lo Fiego, Juan Daniel Coria, María Julia Castro, María Belén Faraoni
Publikováno v:
Chemistry Proceedings, Vol 8, Iss 1, p 107 (2021)
Solanum glaucophyllum is a species of the Solanaceae family that causes enzootic calcinosis by vitamin D3 intoxication in breeding cattle grazing in Argentina. Inspired by thrusting forward the study of the biosynthetic pathway of vitamin D3 in S. gl
Externí odkaz:
https://doaj.org/article/2d2423db7a174647bda2cb03e879dbc0
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Catalytic hydrogenation of terpenes constitutes one of the most interesting reactions in the transformation of natural products. One of the key goals in this synthesis is the selective hydrogenation of the CO bond for obtaining biologically active ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba3554a4400943eeffbbdc96c49fc98
https://doi.org/10.1016/j.jorganchem.2018.10.019
https://doi.org/10.1016/j.jorganchem.2018.10.019
Publikováno v:
The 24th International Electronic Conference on Synthetic Organic Chemistry.
Polyphenols are attracting increasing attention in the discovery of useful agents for the treatment of neurodegenerative diseases. Thelesperma megapotamicum (Spreng.) Kuntze belongs to the family Asteraceae, which is known to have a high antioxidant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b361eadf7b88c266785e0f3b292bbcc
https://doi.org/10.3390/ecsoc-24-08393
https://doi.org/10.3390/ecsoc-24-08393
Autor:
Hyun Ah Jung, Jae Sue Choi, Su Hui Seong, Aditi Wagle, Ana Paula Murray, María Belén Faraoni, María Julia Castro
Publikováno v:
Computational biology and chemistry. 83
Lupane-type triterpenoids have shown a potential effect against neurodegenerative disorders. Alzheimer's disease, one of the common neurodegenerative disease, is evident by the accumulation of amyloid-beta (Aβ) plaque in the extracellular regions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ff172722e2471f858254ebde1016c3
https://pubmed.ncbi.nlm.nih.gov/31442708
https://pubmed.ncbi.nlm.nih.gov/31442708
Autor:
Juan Carlos Calvo, María Julia Castro, Paula Alejandra Sacca, Ana Paula Murray, Valeria P. Careaga, María Belén Faraoni
Publikováno v:
Anticancer research. 39(7)
BACKGROUND/AIM This study examined the potential role of natural triterpenoids lupeol, calenduladiol and heliantriol B2, and a set of 19 derivatives, as antiproliferative and antimetastatic agents against prostate cancer cells. MATERIALS AND METHODS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14032d14c1bde0c16b536c27173900ea
https://pubmed.ncbi.nlm.nih.gov/31262911
https://pubmed.ncbi.nlm.nih.gov/31262911
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
A set of triterpenoids with different grades of oxidation in the lupane skeleton were prepared and evaluated as cholinesterase inhibitors. Allylic oxidation with selenium oxide and Jones’s oxidation were employed to obtain mono-, di- and tri-oxolup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ef4de4c5a208745c6beeb72945b261
https://www.sciencedirect.com/science/article/pii/S0045206818301974?via=ihub
https://www.sciencedirect.com/science/article/pii/S0045206818301974?via=ihub
Autor:
María Belén Faraoni, María Julia Castro, Ana Paula Murray, Carmen Romero, Victoria Richmond, Angel G. Ravelo, Marta S. Maier, Ana Estévez-Braun
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:3341-3350
A set of twenty one lupane derivatives (2–22) was prepared from the natural triterpenoid calenduladiol (1) by transformations on the hydroxyl groups at C-3 and C-16, and also on the isopropenyl moiety. The derivatives were tested for their inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d5b349407970472dd0700d9d23f44a
https://doi.org/10.1016/j.bmc.2014.04.050
https://doi.org/10.1016/j.bmc.2014.04.050
Autor:
Ana Paula Murray, María Julia Castro, María Belén Faraoni, Natalia Paola Alza, Valeria Cavallaro
Publikováno v:
Current Neuropharmacology
As acetylcholinesterase (AChE) inhibitors are an important therapeutic strategy in Alzheimer's disease, efforts are being made in search of new molecules with anti-AChE activity. The fact that naturally-occurring compounds from plants are considered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68347b7809ea47108d00968b1c42dfe2
https://doi.org/10.2174/1570159x11311040004
https://doi.org/10.2174/1570159x11311040004
Publikováno v:
Proceedings of The 18th International Electronic Conference on Synthetic Organic Chemistry.
Alzheimer´s disease (AD) is a progressive neurodegenerative disorder associated with memory impairment and cognitive deficit. It is characterized by low levels of the neurotransmitter acetylcholine (ACh) in the brain of AD patients. The inhibition o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a510fe255fb1b1e363320a186a35426b
https://doi.org/10.3390/ecsoc-18-b035
https://doi.org/10.3390/ecsoc-18-b035