Zobrazeno 1 - 10
of 26
pro vyhledávání: '"María Julia Cambiasso"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Kdm6a is an X-chromosome-linked H3K27me2/3 demethylase that promotes chromatin accessibility and gene transcription and is critical for tissue/cell-specific differentiation. Previous results showed higher Kdm6a levels in XX than in XY hypothalamic ne
Externí odkaz:
https://doaj.org/article/93c4317f054047b99fad3be2fbb028b8
Autor:
Carla Daniela Cisternas, Lucas Ezequiel Cabrera Zapata, María Angeles Arevalo, Luis Miguel Garcia-Segura, María Julia Cambiasso
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract During development sex differences in aromatase expression in limbic regions of mouse brain depend on sex chromosome factors. Genes on the sex chromosomes may affect the hormonal regulation of aromatase expression and this study was undertak
Externí odkaz:
https://doaj.org/article/2228067e4a1b4f5ab88a38099db10d23
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
17β-estradiol (E2) induces axonal growth through extracellular signal-regulated kinase 1 and 2 (ERK1/2)-MAPK cascade in hypothalamic neurons of male rat embryos in vitro, but the mechanism that initiates these events is poorly understood. This study
Externí odkaz:
https://doaj.org/article/70617abb25df427b8760c23aac4718dc
Autor:
Luis G. Aguayo, Carlos Wilson, Lucas Ezequiel Cabrera Zapata, Franco Rafael Mir, María Julia Cambiasso
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Br J Pharmacol
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Br J Pharmacol
Background and Purpose: GABAA receptor functions are dependent on subunit composition, and, through their activation, GABA can exert trophic actions in immature neurons. Although several sex differences in GABA-mediated responses are known to be depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72d755ca72799e4384939abfd8d60b9
https://doi.org/10.1111/bph.15037
https://doi.org/10.1111/bph.15037
Autor:
Lucas E. Cabrera Zapata, Luis Miguel Garcia-Segura, María Julia Cambiasso, Maria Angeles Arevalo
For many decades to date, neuroendocrinologists have delved into the key contribution of gonadal hormones to the generation of sex differences in the developing brain and the expression of sex-specific physiological and behavioral phenotypes in adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4571d10624114348379b915cbee3e1f0
http://hdl.handle.net/10261/305284
http://hdl.handle.net/10261/305284
Autor:
María José Virgolini, Pablo H.H. Lopez, Constanza Feliziani, Mariana Bollo, María Julia Cambiasso
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866:225-239
GM2-gangliosidosis, a subgroup of lysosomal storage disorders, is caused by deficiency of hexosaminidase activity, and comprises the closely related Tay-Sachs and Sandhoff diseases. The enzyme deficiency prevents normal metabolization of ganglioside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5680b1a80ad5ad9a8eaf22bf28d1860f
https://doi.org/10.1016/j.bbamcr.2018.10.014
https://doi.org/10.1016/j.bbamcr.2018.10.014
Autor:
María Julia Cambiasso, Camila Sosa, María Ángeles Arévalo, Lucas Ezequiel Cabrera Zapata, Luis M. Garcia-Segura, Carla D. Cisternas
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cellular and Molecular Life Sciences
instname
Cellular and Molecular Life Sciences
Several X-linked genes are involved in neuronal differentiation and may contribute to the generation of sex dimorphisms in the brain. Previous results showed that XX hypothalamic neurons grow faster, have longer axons, and exhibit higher expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a883f261fc85d82e29f46c4d1de12b58
http://hdl.handle.net/10261/258576
http://hdl.handle.net/10261/258576
Autor:
María Julia Scerbo, Carla D. Cisternas, Lucas Ezequiel Cabrera Zapata, Luis M. Garcia-Segura, Franco Rafael Mir, María Julia Cambiasso, María Ángeles Arévalo
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Hypothalamic neurons show sex differences in neuritogenesis, female neurons have longer axons and higher levels of the neuritogenic factor neurogenin 3 (Ngn3) than male neurons in vitro. Moreover, the effect of 17-ß-estradiol (E2) on axonal growth a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97b85fc459f68f34eaf4a113f505fd2
http://hdl.handle.net/10261/220177
http://hdl.handle.net/10261/220177
Publikováno v:
European Journal of Neuroscience. 45:521-527
GABAA receptor activation exerts trophic actions in immature neurons through depolarization of resting membrane potential. The switch to its classical hyperpolarizing role is developmentally regulated. Previous results suggest that a hormonally biase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6e28252298388bff93b347ecb0589d
https://doi.org/10.1111/ejn.13467
https://doi.org/10.1111/ejn.13467
Publikováno v:
Reproduction (Cambridge, England). 156(4)
In mammals, the reproductive function is controlled by the hypothalamic-pituitary-gonadal axis. During development, mechanisms mediated by gonadal steroids exert an imprinting at the hypothalamic-pituitary level, by establishing sexual differences in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68329b849dfe5038d303ce54431eae9c
https://pubmed.ncbi.nlm.nih.gov/29941464
https://pubmed.ncbi.nlm.nih.gov/29941464