Zobrazeno 1 - 10
of 10
pro vyhledávání: '"María José Lallena"'
Autor:
Carlos Marugán, Natalia Sanz‐Gómez, Beatriz Ortigosa, Ana Monfort‐Vengut, Cristina Bertinetti, Ana Teijo, Marta González, Alicia Alonso de la Vega, María José Lallena, Gema Moreno‐Bueno, Guillermo deCárcer
Publikováno v:
Molecular Oncology, Vol 18, Iss 6, Pp 1531-1551 (2024)
Chromosomal instability (CIN) is a hallmark of cancer aggressiveness, providing genetic plasticity and tumor heterogeneity that allows the tumor to evolve and adapt to stress conditions. CIN is considered a cancer therapeutic biomarker because health
Externí odkaz:
https://doaj.org/article/3ef5cfa6ef0a445999dcca9dcaa443a0
Autor:
Raquel, Torres-Guzmán, Maria Patricia, Ganado, Cecilia, Mur, Carlos, Marugan, Carmen, Baquero, Yanzhu, Yang, Yi, Zeng, Huimin, Bian, Jian, Du, Alfonso, de Dios, Oscar, Puig, María José, Lallena
Publikováno v:
Oncotarget. 13:864-875
Abemaciclib is an oral, selective cyclin-dependent kinase 46 inhibitor (CDK46i), approved for hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced breast cancer (ABC) as monotherapy for endocrine refract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69dab28f3ef5a47efbcef09588aa74ec
https://doi.org/10.18632/oncotarget.28249
https://doi.org/10.18632/oncotarget.28249
Autor:
Sean G. Buchanan, James R. Henry, Robert M. Campbell, Christoph Reinhard, Gregory D. Plowman, David A. Barda, Xiang S. Ye, Hui-Rong Qian, Shaoyou Chu, Thompson Doman, Matthew Z. Dieter, Yu-Hua Hui, Scott W. Eastman, María José Lallena, Carmen Baquero, Carlos Marugán, Michele Dowless, Stephen R. Wasserman, Kenneth Weichert, Anna Pustilnik, Danalyn Manglicmot, Karen Froning, Ann M. Mc Nulty, Stephen Antonysamy, Avnish Kapoor, Li Fan, Chris Ficklin, Huimin Bian, Sufang Yao, Shaoling Jin, Bomie Han, Wayne Blosser, Xi Lin, Robert D. Van Horn, Li-Chun Chio, Philip W. Iversen, Yue Webster, Farhana F. Merzoug, Stephen H. Parsons, Jian Du, Xueqian Gong
LY3295668 chemical characterization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459c3119cab021ba3189b2c2e7d96d2e
https://doi.org/10.1158/2159-8290.22533034.v1
https://doi.org/10.1158/2159-8290.22533034.v1
Autor:
Sean G. Buchanan, James R. Henry, Robert M. Campbell, Christoph Reinhard, Gregory D. Plowman, David A. Barda, Xiang S. Ye, Hui-Rong Qian, Shaoyou Chu, Thompson Doman, Matthew Z. Dieter, Yu-Hua Hui, Scott W. Eastman, María José Lallena, Carmen Baquero, Carlos Marugán, Michele Dowless, Stephen R. Wasserman, Kenneth Weichert, Anna Pustilnik, Danalyn Manglicmot, Karen Froning, Ann M. Mc Nulty, Stephen Antonysamy, Avnish Kapoor, Li Fan, Chris Ficklin, Huimin Bian, Sufang Yao, Shaoling Jin, Bomie Han, Wayne Blosser, Xi Lin, Robert D. Van Horn, Li-Chun Chio, Philip W. Iversen, Yue Webster, Farhana F. Merzoug, Stephen H. Parsons, Jian Du, Xueqian Gong
shRNA suppressor screening data for H446 and MDA-MB-468 cells (tabs 1, 2) and RNA expression level associations with LY3295668 Abs IC50 values from 493 cancer cell lines (tab 3).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7062b69c7f18848d7e882885812c96
https://doi.org/10.1158/2159-8290.22533025.v1
https://doi.org/10.1158/2159-8290.22533025.v1
Autor:
Sean G. Buchanan, James R. Henry, Robert M. Campbell, Christoph Reinhard, Gregory D. Plowman, David A. Barda, Xiang S. Ye, Hui-Rong Qian, Shaoyou Chu, Thompson Doman, Matthew Z. Dieter, Yu-Hua Hui, Scott W. Eastman, María José Lallena, Carmen Baquero, Carlos Marugán, Michele Dowless, Stephen R. Wasserman, Kenneth Weichert, Anna Pustilnik, Danalyn Manglicmot, Karen Froning, Ann M. Mc Nulty, Stephen Antonysamy, Avnish Kapoor, Li Fan, Chris Ficklin, Huimin Bian, Sufang Yao, Shaoling Jin, Bomie Han, Wayne Blosser, Xi Lin, Robert D. Van Horn, Li-Chun Chio, Philip W. Iversen, Yue Webster, Farhana F. Merzoug, Stephen H. Parsons, Jian Du, Xueqian Gong
Supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071e82c7fa2f25274a31dc41f9817c55
https://doi.org/10.1158/2159-8290.22533037
https://doi.org/10.1158/2159-8290.22533037
Autor:
Xueqian Gong, Jian Du, Stephen H. Parsons, Farhana F. Merzoug, Yue Webster, Philip W. Iversen, Li-Chun Chio, Robert D. Van Horn, Xi Lin, Wayne Blosser, Bomie Han, Shaoling Jin, Sufang Yao, Huimin Bian, Chris Ficklin, Li Fan, Avnish Kapoor, Stephen Antonysamy, Ann M. Mc Nulty, Karen Froning, Danalyn Manglicmot, Anna Pustilnik, Kenneth Weichert, Stephen R. Wasserman, Michele Dowless, Carlos Marugán, Carmen Baquero, María José Lallena, Scott W. Eastman, Yu-Hua Hui, Matthew Z. Dieter, Thompson Doman, Shaoyou Chu, Hui-Rong Qian, Xiang S. Ye, David A. Barda, Gregory D. Plowman, Christoph Reinhard, Robert M. Campbell, James R. Henry, Sean G. Buchanan
Publikováno v:
Cancer Discovery. 9:248-263
Loss-of-function mutations in the retinoblastoma gene RB1 are common in several treatment-refractory cancers such as small-cell lung cancer and triple-negative breast cancer. To identify drugs synthetic lethal with RB1 mutation (RB1mut), we tested 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::872b67ff8b99d70e8dd283c21bc27cf8
https://doi.org/10.1158/2159-8290.cd-18-0469
https://doi.org/10.1158/2159-8290.cd-18-0469
Autor:
Xueqian, Gong, Jian, Du, Stephen H, Parsons, Farhana F, Merzoug, Yue, Webster, Philip W, Iversen, Li-Chun, Chio, Robert D, Van Horn, Xi, Lin, Wayne, Blosser, Bomie, Han, Shaoling, Jin, Sufang, Yao, Huimin, Bian, Chris, Ficklin, Li, Fan, Avnish, Kapoor, Stephen, Antonysamy, Ann M, Mc Nulty, Karen, Froning, Danalyn, Manglicmot, Anna, Pustilnik, Kenneth, Weichert, Stephen R, Wasserman, Michele, Dowless, Carlos, Marugán, Carmen, Baquero, María José, Lallena, Scott W, Eastman, Yu-Hua, Hui, Matthew Z, Dieter, Thompson, Doman, Shaoyou, Chu, Hui-Rong, Qian, Xiang S, Ye, David A, Barda, Gregory D, Plowman, Christoph, Reinhard, Robert M, Campbell, James R, Henry, Sean G, Buchanan
Publikováno v:
Cancer discovery. 9(2)
Loss-of-function mutations in the retinoblastoma gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::788f4412d0d9ac102a757d48661f9d4e
https://pubmed.ncbi.nlm.nih.gov/30737214
https://pubmed.ncbi.nlm.nih.gov/30737214
Autor:
Severine Isabelle Gharbi, Laura A. Pelletier, Alfonso Espada, Jesus Gutiérrez, Sonia Maria Gutiérrez Sanfeliciano, Charles T. Rauch, Maria Patricia Ganado, Carmen Baquero, Elisabet Zapatero, Aiping Zhang, Jordi Benach, Anna-Maria Russell, Leticia Cano, Sandra Gomez, Howard Broughton, Nicholas Pulliam, Carmen Maria Perez, Raquel Torres, Marjoke F. Debets, Alfonso de Dios, Oscar Puig, Mark T. Hilgers, Maria Jose Lallena
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Despite the biological and therapeutic relevance of CDK4/6 for the treatment of HR+, HER2- advanced breast cancer, the detailed mode of action of CDK4/6 inhibitors is not completely understood. Of particular interest, phosphorylation of CDK4
Externí odkaz:
https://doaj.org/article/a4901c8cc1f2445081034949720c4383
Autor:
Severine Isabelle Gharbi, Laura A. Pelletier, Alfonso Espada, Jesus Gutiérrez, Sonia Maria Gutiérrez Sanfeliciano, Charles T. Rauch, Maria Patricia Ganado, Carmen Baquero, Elisabet Zapatero, Aiping Zhang, Jordi Benach, Anna-Maria Russell, Leticia Cano, Sandra Gomez, Howard Broughton, Nicholas Pulliam, Carmen Maria Perez, Raquel Torres, Marjoke F. Debets, Alfonso de Dios, Oscar Puig, Mark T. Hilgers, Maria Jose Lallena
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/3b011c3c5bd0459a9b47a137f7b7d6fd
Autor:
David M. Glover, Maria do Carmo Avides, Guillermo de Cárcer, Cayetano Gonzalez, María José Lallena
Publikováno v:
The EMBO journal. 20(11)
We have previously shown that the molecular chaperone heat shock protein 90 (Hsp90) is required to ensure proper centrosome function in Drosophila and vertebrate cells. This observation led to the hypothesis that this chaperone could be required for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4694fafc7cdd17cd4c3218a4358a9a
https://pubmed.ncbi.nlm.nih.gov/11387220
https://pubmed.ncbi.nlm.nih.gov/11387220