Highlights regarding prolactin in the dentate gyrus and hippocampus

Autor: Marta, Carretero-Hernández, Leonardo, Catalano-Iniesta, Enrique J, Blanco, María José, García-Barrado, José, Carretero

Publikováno v: Vitamins and hormones. 118

Prolactin (PRL) is a pituitary hormone that has been typically related to lactogenesis in mammals. However, it has been described over 300 roles in the organism of vertebrae and its relationship with the central nervous system (CNS) is yet to be clar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2485c4120335b2e5849fd0b184cbce59
https://pubmed.ncbi.nlm.nih.gov/35180938

Local transformations of androgens into estradiol by aromatase P450 is involved in the regulation of prolactin and the proliferation of pituitary prolactin-positive cells.

Autor: María José García Barrado, Enrique J Blanco, Marta Carretero Hernández, María Carmen Iglesias Osma, Manuel Carretero, Julio J Herrero, Deborah Jane Burks, José Carretero

Publikováno v: PLoS ONE, Vol 9, Iss 6, p e101403 (2014)

In previous studies we demonstrated the immunohistochemical expression of aromatase in pituitary cells. In order to determine whether pituitary aromatase is involved in the paracrine regulation of prolactin-producing pituitary cells and the physiolog

Externí odkaz: https://doaj.org/article/9650c90992bc4553b0f1f6bb6bd9e9cc

Evidences for Expression and Location of ANGPTL8 in Human Adipose Tissue

Autor: Enrique J. Blanco, María Carmen Iglesias-Osma, Virginia Sánchez Robledo, Marta Carretero-Hernández, María José García-Barrado, José Carretero, Sixto Carrero, Amparo Galán Albiñana, Leonardo Catalano-Iniesta

Publikováno v: Journal of Clinical Medicine; Volume 9; Issue 2; Pages: 512
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 9, Iss 2, p 512 (2020)

The metabolism of triglycerides (TGs) is regulated, among others, by the lipoprotein lipase (LPL) that hydrolyses the TGs on endothelial cells. In turn, LPL is inhibited by the ANGPTLs family of proteins, such as ANGPTL3, 4, and, 8; the latter is the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a101172564e7cb0840112b340b0cd9ff

The lack of Irs2 induces changes in the immunocytochemical expression of aromatase in the mouse retina

Autor: Enrique J. Blanco, María Carmen Iglesias-Osma, Leonardo Catalano-Iniesta, José Carretero, Virginia Sánchez-Robledo, Marta Carretero-Hernández, Blázquez Jl, María José García-Barrado

Publikováno v: Annals of Anatomy - Anatomischer Anzeiger. 239:151726

Insulin receptor substrate (Irs) belongs to a family of proteins that mediate the intracellular signaling of insulin and IGF-1. Insulin receptor substrate 2 (Irs2) is necessary for retinal function, since its failure in Irs2-deficient mice in hypergl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a51126ddecf614914248909fc2c042
https://doi.org/10.1016/j.aanat.2021.151726

Sequential testicular atrophy involves changes in cellular proliferation and apoptosis associated with variations in aromatase P450 expression levels in Irs-2-deficient mice

Autor: María José García-Barrado, José Carretero, Enrique J. Blanco, María Carmen Iglesias-Osma, Marta Carretero-Hernández, Virginia Sánchez-Robledo, Deborah J. Burks, Leonardo Catalano-Iniesta, Teresa Vicente-Garcia

Publikováno v: J Anat

Insulin receptor substrate 2 (Irs‐2) is an intracellular protein susceptible to phosphorylation after activation of the insulin receptor. Its suppression affects testis development and its absence induces peripheral resistance to insulin. The aim o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81f1422179a7fa918ccf3b8a6364d4d
https://pubmed.ncbi.nlm.nih.gov/30474117