Zobrazeno 1 - 10
of 36
pro vyhledávání: '"María José Díaz-Guerra"'
Autor:
José J. García-Ramírez, María José Romero de Ávila, María Luisa Nueda, María José Díaz-Guerra, Natalia Carolina Hernández de León, Susana López-López, Jorge Laborda, Francisco Ruiz-Marcos, Eva M. Monsalve, Victoriano Baladrón
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
NOTCH4 is a member of the NOTCH family of receptors whose expression is intensively induced in macrophages after their activation by Toll-like receptors (TLR) and/or interferon-γ (IFN-γ). In this work, we show that this receptor acts as a negative
Autor:
Francisco Ruiz-Marcos, Julia González-Gómez, Victoriano Baladrón, María Luisa Nueda, María José Romero de Ávila, Isabella Screpanti, María José Díaz-Guerra, Maria Pia Felli, Natalia Carolina Hernández de León, Jorge Laborda, José J. García-Ramírez, Susana López-López, Eva M. Monsalve, María J. García-León
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
instname
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Macrophage activation by Toll receptors is an essential event in the development of the response against pathogens. NOTCH signaling pathway is involved in the control of macrophage activation and the inflammatory processes. In this work, we have char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5bcfee6462b55b07970a3c9d4831d7d
http://hdl.handle.net/10261/237976
http://hdl.handle.net/10261/237976
Autor:
Almudena Ruiz-García, María José Díaz-Guerra, Susana López-López, Jorge Laborda, Pedro Tranque, Susana Mellado, Eva M. Monsalve, José J. García-Ramírez, Elena Caminos, Miriam Fernández
Publikováno v:
European Journal of Immunology. 47:2090-2100
Inhibition of Notch signalling in T cells attenuates the development of experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis. Growing evidence indicates that myeloid cells are also key players in autoimmune processes.
Autor:
Victoriano Baladrón, Laura López-Sanz, José J. García-Ramírez, María José Ruiz-Hidalgo, Jorge Laborda, Susana López-López, Eva M. Monsalve, Ángela Ballesteros, Almudena Ruiz-García, María José Díaz-Guerra
Publikováno v:
The Journal of Immunology. 197:3371-3381
The involvement of NOTCH signaling in macrophage activation by Toll receptors has been clearly established, but the factors and pathways controlling NOTCH signaling during this process have not been completely delineated yet. We have characterized th
Autor:
Jorge Laborda, María José Díaz-Guerra, María-Milagros Rodríguez-Cano, María-Luisa Nueda, María-Julia González-Gómez, Victoriano Baladrón, Beatriz Sánchez-Solana, Eva-María Monsalve
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
The role of NOTCH signaling in adipogenesis is highly controversial, with data indicating null, positive or negative effects on this differentiation process. We hypothesize that these contradictory results could be due to the different global NOTCH s
Autor:
María José Díaz-Guerra, María-Milagros Rodríguez-Cano, Beatriz Sánchez-Solana, María-Julia González-Gómez, Jorge Laborda, María-Luisa Nueda, Victoriano Baladrón, Eva-María Monsalve
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
Scientific Reports
Scientific Reports
The role of NOTCH signaling in adipogenesis is highly controversial, with data indicating null, positive or negative effects on this differentiation process. We hypothesize that these contradictory results could be due to the different global NOTCH s
Autor:
Eva M. Monsalve, José J. García-Ramírez, Jorge Laborda, Samuel Rivero, María José Díaz-Guerra
Publikováno v:
Journal of Molecular Biology. 417:36-50
The epidermal growth factor-like protein DLK2, highly homologous to DLK1, has been identified as a modulator of adipogenesis in vitro. Knocking down Dlk2 expression prevents adipogenesis of 3T3-L1 cells but enhances that of the mesenchymal cell line
Autor:
José J. García-Ramírez, María Luisa Nueda, María José Ruiz-Hidalgo, María Desamparados Ruvira, Jorge Laborda, Victoriano Baladrón, Samuel Rivero, Eva M. Monsalve, María José Díaz-Guerra, Beatriz Sánchez-Solana
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1813:1153-1164
The protein DLK2, highly homologous to DLK1, belongs to the EGF-like family of membrane proteins, which includes NOTCH receptors and their DSL-ligands. The molecular mechanisms by which DLK proteins regulate cell differentiation and proliferation pro
Autor:
María José Ruiz-Hidalgo, María Jesús González González, María José Díaz-Guerra, Eva M. Monsalve, Ricardo Sánchez-Prieto, Almudena Ruiz-García, Jorge Laborda
Publikováno v:
European journal of immunology. 45(9)
Delta-like protein 1 (DLK1) is a noncanonical ligand that inhibits NOTCH1 receptor activity and regulates multiple differentiation processes. In macrophages, NOTCH signaling increases TLR-induced expression of key pro-inflammatory mediators. We have
Autor:
María José Díaz-Guerra, Victoriano Baladrón, Juan Carlos Osorio Gómez, Jorge Laborda, Antonio Rubio, Eva M. Monsalve, Miguel Pérez, José J. García-Ramírez, María José Ruiz-Hidalgo
Publikováno v:
ResearcherID
Notch signaling has been extensively implicated in cell-fate determination along the development of the immune system. However, a role for Notch signaling in fully differentiated immune cells has not been clearly defined. We have analyzed the express