Zobrazeno 1 - 10
of 13
pro vyhledávání: '"María Jimena Salcedo-Arellano"'
Autor:
María Jimena Salcedo-Arellano, Adriana P. Pantoja, Estela M. Muñoz, Verónica Martínez-Cerdeño
Publikováno v:
Frontiers in Neuroanatomy, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/953de963d87344d0b94790a27841ce1b
Autor:
Panhaneath Seng, Federica Alice Maria Montanaro, Hazel Maridith Barlahan Biag, Maria Jimena Salcedo-Arellano, Kyoungmi Kim, Matthew Dominic Ponzini, Flora Tassone, Andrea Schneider, Leonard Abbeduto, Angela John Thurman, David Hessl, Francois V. Bolduc, Sebastien Jacquemont, Sarah Lippé, Randi J. Hagerman
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
IntroductionMetformin has been used as a targeted treatment to potentially improve cognition and slow the typical IQ decline that occurs during development among individuals with fragile X syndrome (FXS). In this follow-up study, we are following the
Externí odkaz:
https://doaj.org/article/cb7ce96699c24474b763bd28cf2d2d6c
Publikováno v:
Gaceta medica de Mexico. 156(1)
Fragile X syndrome is the monogenetic condition that produces more cases of autism and intellectual disability. The repetition of CGG triplets (200) and their methylation entail the silencing of the FMR1 gene. The FMRP protein (product of the FMR1 ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c784d9eac2773abc989b1f2a631ca3b
https://pubmed.ncbi.nlm.nih.gov/32026885
https://pubmed.ncbi.nlm.nih.gov/32026885
Autor:
Maria Jimena Salcedo-Arellano, Michael D. Johnson, Yingratana A. McLennan, Ye Hyun Hwang, Pablo Juarez, Erin Lucille McBride, Adriana P. Pantoja, Blythe Durbin-Johnson, Flora Tassone, Randi J. Hagerman, Verónica Martínez-Cerdeño
Publikováno v:
Cells, Vol 12, Iss 17, p 2132 (2023)
The course of pathophysiological mechanisms involved in fragile X-associated tremor/ataxia syndrome (FXTAS) remains largely unknown. Previous proteomics and metabolomics studies conducted in blood samples collected from FMR1 premutation carriers with
Externí odkaz:
https://doaj.org/article/1eb7a4f2eedc4634bf3f0c2bbfc1131e
Autor:
Jun Yi Wang, Gerard J. Sonico, Maria Jimena Salcedo-Arellano, Randi J. Hagerman, Veronica Martinez-Cerdeno
Publikováno v:
Cells, Vol 12, Iss 14, p 1898 (2023)
Brain changes at the end-stage of fragile X-associated tremor/ataxia syndrome (FXTAS) are largely unknown due to mobility impairment. We conducted a postmortem MRI study of FXTAS to quantify cerebrovascular disease, brain atrophy and iron content, an
Externí odkaz:
https://doaj.org/article/e08e59afce094c16874f9ab6c28665bf
Autor:
Nattaporn Tassanakijpanich, Ana María Cabal-Herrera, Maria Jimena Salcedo-Arellano, Randi Jenssen Hagerman
Publikováno v:
Journal of Biomedicine and Translational Research, Vol 6, Iss 1, Pp 23-33 (2020)
Many targeted treatment studies have been carried out in individuals with Fragile X Syndrome (FXS) guided by animal studies from the Fragile X Mental Retardation 1 (FMR1) knock out (KO) mice and the fragile X Drosophila studies. Here we review the ma
Externí odkaz:
https://doaj.org/article/e75efb3b52fc469bbf4c4b7a35bd2cbe
Autor:
Maria Jimena Salcedo-Arellano, Desiree Sanchez, Jun Yi Wang, Yingratana A. McLennan, Courtney Jessica Clark, Pablo Juarez, Andrea Schneider, Flora Tassone, Randi J. Hagerman, Verónica Martínez-Cerdeño
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
This case documents the co-occurrence of the fragile X-associated tremor ataxia syndrome (FXTAS) and Alzheimer-type neuropathology in a 71-year-old premutation carrier with 85 CGG repeats in the fragile X mental retardation 1 (FMR1) gene, in addition
Externí odkaz:
https://doaj.org/article/499ddbf211c24b5493a9ce5b4545123b
Autor:
Maria Jimena Salcedo-Arellano, Brett Dufour, Yingratana McLennan, Veronica Martinez-Cerdeno, Randi Hagerman
Publikováno v:
Neurobiology of Disease, Vol 136, Iss , Pp 104740- (2020)
This review aims to assemble many years of research and clinical experience in the fields of neurodevelopment and neuroscience to present an up-to-date understanding of the clinical presentation, molecular and brain pathology associated with Fragile
Externí odkaz:
https://doaj.org/article/11bf52c1af8c46c8a265f03f12150f22
Autor:
Dragana D. Protic, Ramkumar Aishworiya, Maria Jimena Salcedo-Arellano, Si Jie Tang, Jelena Milisavljevic, Filip Mitrovic, Randi J. Hagerman, Dejan B. Budimirovic
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 1935 (2022)
Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by the full mutation as well as highly localized methylation of the fragile X mental retardation 1 (FMR1) gene on the long arm of the X chromosome. Children with FXS are commonly co-dia
Externí odkaz:
https://doaj.org/article/763acd7f25fb47e4a3cac84e9528bccc
Autor:
Hazel Maridith B. Biag, Laura A. Potter, Victoria Wilkins, Sumra Afzal, Alexis Rosvall, Maria Jimena Salcedo‐Arellano, Akash Rajaratnam, Ramiro Manzano‐Nunez, Andrea Schneider, Flora Tassone, Susan M. Rivera, Randi J. Hagerman
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 11, Pp n/a-n/a (2019)
Abstract Background Metformin is a drug commonly used in individuals with type 2 diabetes, obesity, and impaired glucose tolerance. It has a strong safety profile in both children and adults. Studies utilizing the Drosophila model and knock out mouse
Externí odkaz:
https://doaj.org/article/7178a3672dca48a98ee5a540a0511c15