Zobrazeno 1 - 10
of 25
pro vyhledávání: '"María Jesús Fernandez-Aceñero"'
Autor:
Aiora Cenigaonandia‐Campillo, Ana Garcia‐Bautista, Anxo Rio‐Vilariño, Arancha Cebrian, Laura delPuerto, José Antonio Pellicer, José Antonio Gabaldón, Horacio Pérez‐Sánchez, Miguel Carmena‐Bargueño, Carolina Meroño, Javier Traba, María Jesús Fernandez‐Aceñero, Natalia Baños‐Herraiz, Lorena Mozas‐Vivar, Estrella Núñez‐Delicado, Jesús Garcia‐Foncillas, Óscar Aguilera
Publikováno v:
Molecular Oncology, Vol 18, Iss 9, Pp 2212-2233 (2024)
In pancreatic ductal adenocarcinoma (PDAC), metabolic rewiring and resistance to standard therapy are closely associated. PDAC cells show enormous requirements for glucose‐derived citrate, the first rate‐limiting metabolite in the synthesis of ne
Externí odkaz:
https://doaj.org/article/15680545600940349d1f3088fd3a5d0b
Autor:
Rubén A. Bartolomé, Laura Pintado-Berninches, Ángela Martín-Regalado, Javier Robles, Tania Calvo-López, Marina Ortega-Zapero, Celia Llorente-Sáez, Issam Boukich, María Jesús Fernandez-Aceñero, J. Ignacio Casal
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Cadherin-17 (CDH17), a marker of differentiation in intestinal cells, binds and activates α2β1 integrin to promote cell adhesion and proliferation in colorectal cancer (CRC) metastasis. Furthermore, CDH17 associates with p120- a
Externí odkaz:
https://doaj.org/article/c966be1e7f0f4d22a3aa627c32f73981
Autor:
Javier Robles, Laura Pintado‐Berninches, Issam Boukich, Beatriz Escudero, Vivian de losRios, Rubén A Bartolomé, Marta Jaén, Ángela Martín‐Regalado, María Jesús Fernandez‐Aceñero, Juan Ignacio Imbaud, José Ignacio Casal
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 6, Pp 495-508 (2022)
Abstract The necessity to accurately predict recurrence and clinical outcome in early stage colorectal cancer (CRC) is critical to identify those patients who may benefit from adjuvant chemotherapy. Here, we developed and validated a gene‐based ris
Externí odkaz:
https://doaj.org/article/b7b96c02512a43f4b84ef71ae7a7c2d1
Autor:
J. Ignacio Casal, Sofia Torres, María Jesús Fernandez-Aceñero, Rubén A. Bartolomé, Rodrigo Barderas
Autocrine secretion of cytokines by metastatic colorectal cancer cells and their role during invasion and liver homing has been poorly characterized. In this study, we used cytokine arrays to analyze the secretomes of poorly and highly metastatic col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e8f3ace59b27c5dbc2483831726d775
https://doi.org/10.1158/0008-5472.c.6502853.v1
https://doi.org/10.1158/0008-5472.c.6502853.v1
Autor:
J. Ignacio Casal, Sofia Torres, María Jesús Fernandez-Aceñero, Rubén A. Bartolomé, Rodrigo Barderas
(338 KB) - Supplementary Table S1. Clinical data of colon cancer samples used for immunohistochemical and survival analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20070827f51806cbb751d794d751a039
https://doi.org/10.1158/0008-5472.22390163.v1
https://doi.org/10.1158/0008-5472.22390163.v1
Autor:
J. Ignacio Casal, Sofia Torres, María Jesús Fernandez-Aceñero, Rubén A. Bartolomé, Rodrigo Barderas
(271 KB) - Supplementary Figure S1. Expression of IL4R� and IL13R�1 in KM12 cells. Supplementary Figure S2. IL-13 quantification in conditioned medium of KM12 cells. Supplementary Figure S3. IL13R�1 is not involved in cell migration and invasio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a256819a067bbb3110ddb8e788bfe3ab
https://doi.org/10.1158/0008-5472.22390169.v1
https://doi.org/10.1158/0008-5472.22390169.v1
Autor:
J. Ignacio Casal, Sofia Torres, María Jesús Fernandez-Aceñero, Rubén A. Bartolomé, Rodrigo Barderas
(116 KB) - Additional methods information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8963ffe2b2ce139374e4a6f33e813d34
https://doi.org/10.1158/0008-5472.22390166
https://doi.org/10.1158/0008-5472.22390166
Autor:
José Manuel García-Martínez, Ana Chocarro-Calvo, Javier Martínez-Useros, María Jesús Fernández-Aceñero, M Carmen Fiuza, José Cáceres-Rentero, Antonio De la Vieja, Antonio Barbáchano, Alberto Muñoz, María Jesús Larriba, Custodia García-Jiménez
Publikováno v:
eLife, Vol 12 (2023)
Posttranslational modifications of epigenetic modifiers provide a flexible and timely mechanism for rapid adaptations to the dynamic environment of cancer cells. SIRT1 is an NAD+-dependent epigenetic modifier whose activity is classically associated
Externí odkaz:
https://doaj.org/article/f3a455fa9b724e539e76a6e968190b0d
Autor:
Sofía, Torres, Irene, Garcia-Palmero, Rubén A, Bartolomé, María Jesús, Fernandez-Aceñero, Elena, Molina, Eva, Calviño, Miguel F, Segura, J Ignacio, Casal
Publikováno v:
The Journal of pathology. 242(1)
The process of liver colonization in colorectal cancer remains poorly characterized. Here, we addressed the role of microRNA (miRNA) dysregulation in metastasis. We first compared miRNA expression profiles between colorectal cancer cell lines with di
Autor:
María Garranzo‐Asensio, Javier Rodríguez‐Cobos, Coral San Millán, Carmen Poves, María Jesús Fernández‐Aceñero, Daniel Pastor‐Morate, David Viñal, Ana Montero‐Calle, Guillermo Solís‐Fernández, María‐Ángeles Ceron, Manuel Gámez‐Chiachio, Nuria Rodríguez, Ana Guzmán‐Aránguez, Rodrigo Barderas, Gemma Domínguez
Publikováno v:
Molecular Oncology, Vol 16, Iss 14, Pp 2672-2692 (2022)
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer‐related death worldwide. Alterations in proteins of the p53‐family are a common event in CRC. ΔNp73, a p53‐family member, shows oncogenic properties
Externí odkaz:
https://doaj.org/article/234f5c92fcf7483793358afcfa781355