Zobrazeno 1 - 10
of 169
pro vyhledávání: '"María Jesús Fernández‐Aceñero"'
Autor:
José Manuel García-Martínez, Ana Chocarro-Calvo, Javier Martínez-Useros, María Jesús Fernández-Aceñero, M Carmen Fiuza, José Cáceres-Rentero, Antonio De la Vieja, Antonio Barbáchano, Alberto Muñoz, María Jesús Larriba, Custodia García-Jiménez
Publikováno v:
eLife, Vol 12 (2023)
Posttranslational modifications of epigenetic modifiers provide a flexible and timely mechanism for rapid adaptations to the dynamic environment of cancer cells. SIRT1 is an NAD+-dependent epigenetic modifier whose activity is classically associated
Externí odkaz:
https://doaj.org/article/f3a455fa9b724e539e76a6e968190b0d
Autor:
María Garranzo‐Asensio, Javier Rodríguez‐Cobos, Coral San Millán, Carmen Poves, María Jesús Fernández‐Aceñero, Daniel Pastor‐Morate, David Viñal, Ana Montero‐Calle, Guillermo Solís‐Fernández, María‐Ángeles Ceron, Manuel Gámez‐Chiachio, Nuria Rodríguez, Ana Guzmán‐Aránguez, Rodrigo Barderas, Gemma Domínguez
Publikováno v:
Molecular Oncology, Vol 16, Iss 14, Pp 2672-2692 (2022)
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer‐related death worldwide. Alterations in proteins of the p53‐family are a common event in CRC. ΔNp73, a p53‐family member, shows oncogenic properties
Externí odkaz:
https://doaj.org/article/234f5c92fcf7483793358afcfa781355
Autor:
Ana Montero-Calle, Sofía Jiménez de Ocaña, Ruth Benavente-Naranjo, Raquel Rejas-González, Rubén A. Bartolomé, Javier Martínez-Useros, Rodrigo Sanz, Jana Dziaková, María Jesús Fernández-Aceñero, Marta Mendiola, José Ignacio Casal, Alberto Peláez-García, Rodrigo Barderas
Publikováno v:
Cells, Vol 12, Iss 21, p 2548 (2023)
SPRY domain-containing protein 7 (SPRYD7) is a barely known protein identified via spatial proteomics as being upregulated in highly metastatic-to-liver KM12SM colorectal cancer (CRC) cells in comparison to its isogenic poorly metastatic KM12C CRC ce
Externí odkaz:
https://doaj.org/article/4ba87d93cedc4013968dcac0ed1737bc
Autor:
Ana Montero-Calle, Itziar Aranguren-Abeigon, María Garranzo-Asensio, Carmen Poves, María Jesús Fernández-Aceñero, Javier Martínez-Useros, Rodrigo Sanz, Jana Dziaková, Javier Rodriguez-Cobos, Guillermo Solís-Fernández, Eloy Povedano, Maria Gamella, Rebeca Magnolia Torrente-Rodríguez, Miren Alonso-Navarro, Vivian de los Ríos, J. Ignacio Casal, Gemma Domínguez, Ana Guzman-Aranguez, Alberto Peláez-García, José Manuel Pingarrón, Susana Campuzano, Rodrigo Barderas
Publikováno v:
Engineering, Vol 7, Iss 10, Pp 1393-1412 (2021)
Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide. The five-year survival rate of CRC patients depends on the stage at diagnosis, being higher than 80% when CRC is diagnosed in the early stages but lower than 10% w
Externí odkaz:
https://doaj.org/article/37d8fc52650e413c80d384b5a7c4075f
Autor:
Ana Montero-Calle, Marta Gómez de Cedrón, Adriana Quijada-Freire, Guillermo Solís-Fernández, Victoria López-Alonso, Isabel Espinosa-Salinas, Alberto Peláez-García, María Jesús Fernández-Aceñero, Ana Ramírez de Molina, Rodrigo Barderas
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Approximately 25% of colorectal cancer (CRC) patients experience systemic metastases, with the most frequent target organs being the liver and lung. Metabolic reprogramming has been recognized as one of the hallmarks of cancer. Here, metabolic and fu
Externí odkaz:
https://doaj.org/article/050b971bb1f84d0ca089a7952ddb0af1
Autor:
Ana Montero-Calle, María Garranzo-Asensio, Rebeca M. Torrente-Rodríguez, Víctor Ruiz-Valdepeñas Montiel, Carmen Poves, Jana Dziaková, Rodrigo Sanz, Cristina Díaz del Arco, José Manuel Pingarrón, María Jesús Fernández-Aceñero, Susana Campuzano, Rodrigo Barderas
Publikováno v:
Cancers, Vol 15, Iss 7, p 2102 (2023)
Colorectal cancer (CRC) is the third most common cancer and the second most frequent cause of cancer-related death worldwide. The detection in plasma samples of autoantibodies against specific tumor-associated antigens has been demonstrated to be use
Externí odkaz:
https://doaj.org/article/2c64b4d8f4c24eddb953597d5d21ab1b
Autor:
Diego Martínez-Rey, Lorena Carmona-Rodríguez, María Jesús Fernández-Aceñero, Emilia Mira, Santos Mañes
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Tumor-infiltrating lymphocytes (TILs) are major players in the immune-mediated control of cancer and the response to immunotherapy. In primary cancers, however, TILs are commonly absent, suggesting T-cell entry into the tumor microenvironment (TME) t
Externí odkaz:
https://doaj.org/article/b417d188debd41f3bf1f0a3b9c958dda
Autor:
Guillermo Solís-Fernández, Ana Montero-Calle, Javier Martínez-Useros, Álvaro López-Janeiro, Vivian de los Ríos, Rodrigo Sanz, Jana Dziakova, Elena Milagrosa, María Jesús Fernández-Aceñero, Alberto Peláez-García, José Ignacio Casal, Johan Hofkens, Susana Rocha, Rodrigo Barderas
Publikováno v:
Cells, Vol 11, Iss 3, p 447 (2022)
Metastasis is the primary cause of colorectal cancer (CRC) death. The liver and lung, besides adjacent lymph nodes, are the most common sites of metastasis. Here, we aimed to study the lymph nodes, liver, and lung CRC metastasis by quantitative spati
Externí odkaz:
https://doaj.org/article/10dbe3a3d12d45e6b99b5cba4c44716f
Autor:
María Gutiérrez-Salmerón, José Manuel García-Martínez, Javier Martínez-Useros, María Jesús Fernández-Aceñero, Benoit Viollet, Severine Olivier, Jagat Chauhan, Silvia R Lucena, Antonio De la Vieja, Colin R Goding, Ana Chocarro-Calvo, Custodia García-Jiménez
Publikováno v:
PLoS Biology, Vol 18, Iss 6, p e3000732 (2020)
Coordination of gene expression with nutrient availability supports proliferation and homeostasis and is shaped by protein acetylation. Yet how physiological/pathological signals link acetylation to specific gene expression programs and whether such
Externí odkaz:
https://doaj.org/article/d6b95076bfc94e6c82999824a59bfd60
Autor:
Sandra Pérez-Rial, Esther Barreiro, María Jesús Fernández-Aceñero, María Encarnación Fernández-Valle, Nicolás González-Mangado, Germán Peces-Barba
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234606 (2020)
Skeletal muscle dysfunction is a common complication and an important prognostic factor in patients with chronic obstructive pulmonary disease (COPD). It is associated with intrinsic muscular abnormalities of the lower extremities, but it is not know
Externí odkaz:
https://doaj.org/article/ca705314ca924b1199bbeb105239107a