Zobrazeno 1 - 10
of 161
pro vyhledávání: '"María Jesús, Fernández Aceñero"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 6440-6471 (2024)
Despite recent campaigns for screening and the latest advances in cancer therapy and molecular biology, gastrointestinal (GI) neoplasms remain among the most frequent and lethal human tumors. Most GI neoplasms are sporadic, but there are some well-kn
Externí odkaz:
https://doaj.org/article/abae4a9a28254f169eeca3fdd0cc009b
Autor:
Nerea Huertos Soto, Juan Manuel Gómez Cervantes, María Jesús Fernández Aceñero, María del Carmen Soto Beauregard
Publikováno v:
Laboratory Animal Research, Vol 40, Iss 1, Pp 1-11 (2024)
Abstract Background Necrotizing enterocolitis (NEC) is a severe inflammatory bowel disease in neonates. Our group has developed an experimental model of NEC, with an effectiveness of 73%. Cannabidiol (CBD) is an innovative treatment for neonatal cere
Externí odkaz:
https://doaj.org/article/e2580261ed214e9a80dca270387e51af
Autor:
Cristina Díaz del Arco, Lourdes Estrada Muñoz, María de los Ángeles Cerón Nieto, Elena Molina Roldán, María Jesús Fernández Aceñero, Soledad García Gómez de las Heras
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1508 (2024)
Galectin-1 (Gal-1), a member of the human lectin family, has garnered attention for its association with aggressive behavior in human tumors, prompting research into the development of targeted drugs. This study aims to assess the staining pattern an
Externí odkaz:
https://doaj.org/article/14a4b9ee5a594f39bf8f2c95f16a1e1c
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2649 (2024)
Gastric cancer (GC) is a heterogeneous disease, often diagnosed at advanced stages, with a 5-year survival rate of approximately 20%. Despite notable technological advancements in cancer research over the past decades, their impact on GC management a
Externí odkaz:
https://doaj.org/article/ac90494b76584148ab5a70a5dbd2fe45
Autor:
José Manuel García-Martínez, Ana Chocarro-Calvo, Javier Martínez-Useros, María Jesús Fernández-Aceñero, M Carmen Fiuza, José Cáceres-Rentero, Antonio De la Vieja, Antonio Barbáchano, Alberto Muñoz, María Jesús Larriba, Custodia García-Jiménez
Publikováno v:
eLife, Vol 12 (2023)
Posttranslational modifications of epigenetic modifiers provide a flexible and timely mechanism for rapid adaptations to the dynamic environment of cancer cells. SIRT1 is an NAD+-dependent epigenetic modifier whose activity is classically associated
Externí odkaz:
https://doaj.org/article/f3a455fa9b724e539e76a6e968190b0d
Autor:
María Garranzo‐Asensio, Javier Rodríguez‐Cobos, Coral San Millán, Carmen Poves, María Jesús Fernández‐Aceñero, Daniel Pastor‐Morate, David Viñal, Ana Montero‐Calle, Guillermo Solís‐Fernández, María‐Ángeles Ceron, Manuel Gámez‐Chiachio, Nuria Rodríguez, Ana Guzmán‐Aránguez, Rodrigo Barderas, Gemma Domínguez
Publikováno v:
Molecular Oncology, Vol 16, Iss 14, Pp 2672-2692 (2022)
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer‐related death worldwide. Alterations in proteins of the p53‐family are a common event in CRC. ΔNp73, a p53‐family member, shows oncogenic properties
Externí odkaz:
https://doaj.org/article/234f5c92fcf7483793358afcfa781355
Autor:
Ana Montero-Calle, Sofía Jiménez de Ocaña, Ruth Benavente-Naranjo, Raquel Rejas-González, Rubén A. Bartolomé, Javier Martínez-Useros, Rodrigo Sanz, Jana Dziaková, María Jesús Fernández-Aceñero, Marta Mendiola, José Ignacio Casal, Alberto Peláez-García, Rodrigo Barderas
Publikováno v:
Cells, Vol 12, Iss 21, p 2548 (2023)
SPRY domain-containing protein 7 (SPRYD7) is a barely known protein identified via spatial proteomics as being upregulated in highly metastatic-to-liver KM12SM colorectal cancer (CRC) cells in comparison to its isogenic poorly metastatic KM12C CRC ce
Externí odkaz:
https://doaj.org/article/4ba87d93cedc4013968dcac0ed1737bc
Autor:
Ana Montero-Calle, Itziar Aranguren-Abeigon, María Garranzo-Asensio, Carmen Poves, María Jesús Fernández-Aceñero, Javier Martínez-Useros, Rodrigo Sanz, Jana Dziaková, Javier Rodriguez-Cobos, Guillermo Solís-Fernández, Eloy Povedano, Maria Gamella, Rebeca Magnolia Torrente-Rodríguez, Miren Alonso-Navarro, Vivian de los Ríos, J. Ignacio Casal, Gemma Domínguez, Ana Guzman-Aranguez, Alberto Peláez-García, José Manuel Pingarrón, Susana Campuzano, Rodrigo Barderas
Publikováno v:
Engineering, Vol 7, Iss 10, Pp 1393-1412 (2021)
Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide. The five-year survival rate of CRC patients depends on the stage at diagnosis, being higher than 80% when CRC is diagnosed in the early stages but lower than 10% w
Externí odkaz:
https://doaj.org/article/37d8fc52650e413c80d384b5a7c4075f
Autor:
Míriam Gené, Míriam Cuatrecasas, Irene Amat, Jesús Alberto Veiga, María Jesús Fernández Aceñero, Victòria Fusté Chimisana, Jordi Tarragona, Ismael Jurado, Rebeca Fernández-Victoria, Carolina Martínez Ciarpaglini, Cristina Alenda González, Carlos Zac, Pilar Ortega de la Obra, María Teresa Fernández-Figueras, Manel Esteller, Eva Musulen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8655 (2023)
Colitis-associated colorectal carcinoma (CAC) occurs in inflammatory bowel disease (IBD) because of the “chronic inflammation-dysplasia-cancer” carcinogenesis pathway characterized by p53 alterations in the early stages. Recently, gastric metapla
Externí odkaz:
https://doaj.org/article/0ee26b96b093432a8be8039b7f529be1
Autor:
Ana Montero-Calle, Marta Gómez de Cedrón, Adriana Quijada-Freire, Guillermo Solís-Fernández, Victoria López-Alonso, Isabel Espinosa-Salinas, Alberto Peláez-García, María Jesús Fernández-Aceñero, Ana Ramírez de Molina, Rodrigo Barderas
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Approximately 25% of colorectal cancer (CRC) patients experience systemic metastases, with the most frequent target organs being the liver and lung. Metabolic reprogramming has been recognized as one of the hallmarks of cancer. Here, metabolic and fu
Externí odkaz:
https://doaj.org/article/050b971bb1f84d0ca089a7952ddb0af1