Zobrazeno 1 - 10
of 161
pro vyhledávání: '"María J. Vicent"'
Autor:
José A. López‐Guerrero, Mar Valés‐Gómez, Francesc E. Borrás, Juan Manuel Falcón‐Pérez, María J. Vicent, María Yáñez‐Mó
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 4, Pp n/a-n/a (2023)
Abstract The standardization of clinical studies using extracellular vesicles (EVs) has mainly focused on the procedures employed for their isolation and characterization; however, preanalytical aspects of sample collection, handling and storage also
Externí odkaz:
https://doaj.org/article/666db4acea554510b03398aa4a00f80f
Autor:
Paula M. Soriano-Teruel, Guillermo García‑Laínez, María Marco-Salvador, Julián Pardo, Maykel Arias, Christian DeFord, Irmgard Merfort, María J. Vicent, Pablo Pelegrín, Mónica Sancho, Mar Orzáez
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-11 (2021)
Abstract The ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain (CARD)) protein is an scaffold component of different inflammasomes, intracellular multiprotein platforms of the innate immune system that are activated
Externí odkaz:
https://doaj.org/article/c361d801ae99439eadad5e0ee61b113a
Autor:
Esther Giraldo, Pablo Bonilla, Mara Mellado, Pablo Garcia-Manau, Carlota Rodo, Ana Alastrue, Eric Lopez, Elena Carreras Moratonas, Ferran Pellise, Snežana Đorđević, María J. Vicent, Victoria Moreno Manzano
Publikováno v:
Cells, Vol 11, Iss 20, p 3304 (2022)
Neural precursor cell (NPC) transplantation represents a promising therapy for treating spinal cord injuries (SCIs); however, despite successful results obtained in preclinical models, the clinical translation of this approach remains challenging due
Externí odkaz:
https://doaj.org/article/78269584f3e34bcb995a72c0c97460e8
Publikováno v:
Polymers, Vol 6, Iss 2, Pp 515-551 (2014)
Polypeptides are envisaged to achieve a major impact on a number of different relevant areas such as biomedicine and biotechnology. Acquired knowledge and the increasing interest on amino acids, peptides and proteins is establishing a large panel of
Externí odkaz:
https://doaj.org/article/c3a080ffaace45b19f98ba8bcd83aa3e
Autor:
Tetiana Melnyk, Esther Masiá, Oleksandr Zagorodko, Inmaculada Conejos-Sánchez, María J. Vicent
Publikováno v:
Journal of Controlled Release. 355:385-394
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f3a1d6117f0bd8b8012e8d3f61edd9f
https://doi.org/10.1016/j.jconrel.2023.01.079
https://doi.org/10.1016/j.jconrel.2023.01.079
Autor:
Pablo Scodeller, María J. Vicent, Tambet Teesalu, Pärt Peterson, Liis Salumäe, Snežana Đorđević, Mauro Bringas, Monica Pickholz, Eliana K. Asciutto, Uku Haljasorg, Alessio Malfanti, Anni Lepland
Although many studies have explored the depletion of tumor-associated macrophages (TAM) as a therapeutic strategy for solid tumors, currently available compounds suffer from poor efficacy and dose-limiting side effects. Here, we developed a novel TAM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32713650f8868ae14e3a5e6b32fb405b
https://doi.org/10.1158/2767-9764.c.6550709
https://doi.org/10.1158/2767-9764.c.6550709
Autor:
Pablo Scodeller, María J. Vicent, Tambet Teesalu, Pärt Peterson, Liis Salumäe, Snežana Đorđević, Mauro Bringas, Monica Pickholz, Eliana K. Asciutto, Uku Haljasorg, Alessio Malfanti, Anni Lepland
One .docx word file containing the following information:Scheme S1. Synthetic approach for St-PGA-OG-mUNO.Scheme S2. Synthetic approach for OximUNO.Video S1. Fifty ns MD trajectory of St-PGA in solution.Table S1. St-PGA-OG-mUNO and St-PGA-OG dye load
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469da832490cc8b083c300cb35ab307f
https://doi.org/10.1158/2767-9764.22544636
https://doi.org/10.1158/2767-9764.22544636
Publikováno v:
Polymer Chemistry. 13:718-735
Gene therapy has emerged as a technique with the potential to treat human diseases; however, examples of the topical application of gene therapy as treatment for skin diseases remain scarce due to difficulties associated with the nature of the skin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6147496217bcb1010428d3a42098ae84
https://doi.org/10.1039/d1py01485d
https://doi.org/10.1039/d1py01485d
Publikováno v:
Drug Discovery Today
The success of preclinical drug discovery strongly relies on the ability of experimental models to resemble human pathophysiology. The number of compounds receiving approval for clinical use is limited, and this has led to the development of more phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e363e909a84871491a5207ab5adf86d
https://doi.org/10.1016/j.drudis.2021.02.024
https://doi.org/10.1016/j.drudis.2021.02.024
Publikováno v:
Advanced Drug Delivery Reviews
Graphical abstract
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at the clinical trial stage. Limitations of conven
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at the clinical trial stage. Limitations of conven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76811ce2af0ea0f7b3342230007c3c01
https://doi.org/10.1016/j.addr.2021.03.018
https://doi.org/10.1016/j.addr.2021.03.018