Zobrazeno 1 - 10
of 38
pro vyhledávání: '"María J. R. Yunta"'
Autor:
Eudald Carbonell, Roberto Tejero, María J. R. Yunta, Enrique García-España, Lucrecia Campayo, Fernando Gómez-Contreras, Mercedes Cano, Cristina Galiana-Roselló, Álvaro Martínez-Camarena, Ana M. Sanz, Mario Inclán, Jorge González-García, Pilar Navarro
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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The affinity and the binding mode of two benzo[g]phthalazine compounds, functionalized with one or two 2-(imidazole-4-yl)-ethylamine groups, to DNA and RNA models have been evaluated by means of UV-Vis, fluorescence and circular dichroism (CD) spectr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a5d40939b490030d28f37255ea4880
https://doi.org/10.1039/c8nj05039b
https://doi.org/10.1039/c8nj05039b
Autor:
Manuel Sánchez-Moreno, Kristina Kolodova, Carmen Cano, María José Rosales-Lombardo, María J. R. Yunta, Lucrecia Campayo, Ana M. Sanz, Lucía de Andrés-Gordo, Álvaro Martín-Montes, Alberto Gómez-Muñoz, Clotilde Marín
Publikováno v:
Digibug. Repositorio Institucional de la Universidad de Granada
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The authors thank the MCINN Project CTQ2009-14288-C04-01 for financial support. We are also grateful to the NMR and Elemental Analysis C.A.I.s of the Universidad Complutense (Madrid), and to the Transmission-electron microscopy and Nuclear magnetic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51dde5bebf5e553275be304a8520de8d
http://hdl.handle.net/10481/71408
http://hdl.handle.net/10481/71408
Autor:
María J. R. Yunta
Publikováno v:
American Journal of Modeling and Optimization. 2:84-102
Protonation states are sometimes crucial for free energy calculations to predict binding ability of molecules to receptors, a main subject for drug design. This mini-review seeks to identify the importance of knowing the influence of pH in such studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daeeca0d8328d2b1b50a76b503551e06
https://doi.org/10.12691/ajmo-2-4-1
https://doi.org/10.12691/ajmo-2-4-1
Autor:
Pilar Navarro, Clotilde Marín, Ramón Gutiérrez-Sánchez, Fernando Gómez-Contreras, Manuel Sánchez-Moreno, María J. R. Yunta, Francisco Olmo, María José Rosales, Enrique García-España, Inmaculada Ramírez-Macías
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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The in vitro leishmanicidal activity and cytotoxicity of pyrazole-containing macrocyclic polyamines 1-4 was assayed on Leishmania infantum and Leishmania braziliensis species. Compounds 1-4 were more active and less toxic than glucantime and both inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd65d03b12ef2c7bf480ab29bbd81f25
https://doi.org/10.1017/s0031182014000201
https://doi.org/10.1017/s0031182014000201
Publikováno v:
Molecular Informatics. 38:1900052
Computational techniques are widely used to reduce costs associated with new drug development with the ability to bind a specific molecular target. These studies need a Brookhaven protein data bank structure sample of the enzyme interaction with an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2ece3f2d3b1c1bd5920ed60ea17b17
https://doi.org/10.1002/minf.201900052
https://doi.org/10.1002/minf.201900052
Autor:
Enrique Ortí, Antonio Domènech, Enrique García-España, Juan C. Frias, María J. R. Yunta, Rubén D. Costa, M. Teresa Albelda, Pilar Navarro, Felipe Reviriego
Publikováno v:
Organic Letters. 10:5099-5102
The synthesis and steady-state fluorescence studies on the interaction with AMPH, METH, MDMA, and DA of two diazatetraester pyrazole crowns containing appended N-(9H-fluoren-9-yl) and N-(naphth-2-ylmethyl) functions, in a water/ethanol 70:30 mixture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f044127663103ca90ed6a845dc0130b8
https://doi.org/10.1021/ol801732t
https://doi.org/10.1021/ol801732t
Autor:
María José Rosales, Carmen Cano, Manuel Sánchez-Moreno, Francisco Olmo, David Martín-Oliva, Pilar Navarro, Lucrecia Campayo, María J. R. Yunta, Fernando Gómez-Contreras, Clotilde Marín
Publikováno v:
European journal of medicinal chemistry. 106
A series of new phthalazine derivatives (1-4) containing imidazole rings and functionalized with nitro groups in the benzene ring of the phthalazine moiety were prepared and identified on the basis of their MS, elemental analyses and bidimensional (1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4b6bea5af84579c9c6fc460b54540c
https://pubmed.ncbi.nlm.nih.gov/26523668
https://pubmed.ncbi.nlm.nih.gov/26523668
Autor:
Francisco Olmo, María J. R. Yunta, Ana M. Sanz, Manuel Sánchez-Moreno, Inmaculada Ramírez-Macías, Fernando Gómez-Contreras, Clotilde Marín, Lucrecia Campayo, Carmen Cano, Pilar Navarro
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Objectives: To evaluate the in vitro leishmanicidal activity of imidazole-based (1-4) and pyrazole-based (5-6) benzo[g]phthalazine derivatives against Leishmania infantum and Leishmania braziliensis. Methods: The in vitro activity of compounds 1-6 wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7430064d9880d9a6beec28a03babe7e9
http://hdl.handle.net/10261/121583
http://hdl.handle.net/10261/121583
Autor:
María J. R. Yunta, Manuel Sánchez-Moreno, Lucrecia Campayo, Inmaculada Ramírez-Macías, Carmen Cano, Ana M. Sanz, Clotilde Marín, Fernando Gómez-Contreras, María José Rosales, Pilar Navarro
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
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The in vitro leishmanicidal activity of a series of imidazole-containing phthalazine derivatives 1-4 was tested on Leishmania infantum, Leishmania braziliensis and Leishmania donovani parasites, and their cytotoxicity on J774·2 macrophage cells was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37aba162579212d73bbf2272ba7c1930
http://hdl.handle.net/10261/117717
http://hdl.handle.net/10261/117717
Autor:
María J. R. Yunta, Enrique García-España, Pilar Navarro, Francisco Lloret, Julio Latorre, Hermas R. Jiménez, Laurent Lamarque, Carlos Miranda, Francisco Escartí
Publikováno v:
European Journal of Inorganic Chemistry. 2005:189-208
The synthesis of a new macrocyclic receptor (L 4 ) containing two 3,5-dimethylpyrazole units connected by dipropylenetriamine bridges is reported for the first time; pH-metric titrations indicate that L 4 shows six protonation steps in the pH range 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::394e7a34d421e7dd5a30efbe2f5e90eb
https://doi.org/10.1002/ejic.200400671
https://doi.org/10.1002/ejic.200400671