Identification of a truncated β1-chimaerin variant that inactivates nuclear Rac1

Autor: María J. Caloca, Laura Barrio-Real, Rogelio González-Sarmiento, Eladio Velasco, Victoria Casado-Medrano, Marcelo G. Kazanietz, Laura Gutiérrez-Miranda

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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J Biol Chem

β1-chimaerin belongs to the chimaerin family of GTPase-activating proteins (GAPs) and is encoded by the CHN2 gene, which also encodes the β2- and β3-chimaerin isoforms. All chimaerin isoforms have a C1 domain that binds diacylglycerol as well as t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09306f77090cc0845dba16c899968a0
https://doi.org/10.1016/s0021-9258(17)49887-5

The role of Rac in tumor susceptibility and disease progression: from biochemistry to the clinic

Autor: Cynthia Lopez-Haber, Mariana Cooke, Martin J. Baker, María J. Caloca, Shaofei Wang, Victoria Casado-Medrano, Marcelo G. Kazanietz

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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The family of Rho GTPases are involved in the dynamic control of cytoskeleton reorganization and other fundamental cellular functions, including growth, motility, and survival. Rac1, one of the best characterized Rho GTPases, is an established effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b9599db2defe7a3ee25297c2c6b311
http://hdl.handle.net/10261/196952

List of Contributors

Autor: Ricardo Abadie-Guedes, Anissa Abi-Dargham, Osama A. Abulseoud, Jelena Acevska, Ana Adan, María A. Aguilar, Maryam Akhgari, Robert Ali, Amelia J. Anderson-Mooney, Muhammad Anees, M. Carmen Arenas, Jamie Arndt, Daniele Ascheri, Nida Ashraf, Maxie Ashton, Olga Asimaki, Jean-Michel Aubry, Harinder Aujla, A. George Awad, Mahmoud A. Awara, Ana Bagues, Yatan P.S. Balhara, Francis Bambico, Laura Barrio-Real, Selena E. Bartlett, Balapal S. Basavarajappa, Aniruddha Basu, Claiton H.D. Bau, Matthew C. Beattie, Benjamin Becker, Anton L. Beer, Deepak Behera, Irina Benaiges, Dessa Bergen-Cico, Susan E. Bergeson, Wade H. Berrettini, Leandro J. Bertoglio, Charles S. Bockman, Stefan Borgwardt, Josiane Bourque, Muge Bozkurt, Katharine Alexandra Brennan, Hilary Briggs, Samanth J. Brooks, Rachel Picada Bulcão, Ute Burkhardt, Tracy R. Butler, Eduardo Rodrigues Cabrera, Daniela Caldirola, Russell C. Callaghan, Elza Callegari, María J. Caloca, Alline C. Campos, Carla Cannizzaro, Gavin Cape, Benjamin L. Carnell, Javier R. Caso, Lucas Henrique Cendron, Yun-Hsuan Chang, Gordon L.F. Cheng, Kao Chin Chen, Kanwaljit Chopra, Tony C.H. Chow, Rachael Cico, Jason B. Cook, Maurizio Coppola, Jose A. Cortes-Briones, Janna Cousijn, Richard C. Crist, Candice E. Crocker, Kirsty Danielson, Miguel Dasilva, Malay Dave, Mariella De Biasi, Cristiane R. de Carvalho, François De Guio, Dirk De Ridder, Sonia Dhiman, Giuseppina Diaferia, Marco Diana, Joseph R. DiFranza, Aneta Dimitrovska, Le-Anh Dinh-Williams, Maja Djurendic-Brenesel, Jonathan N. Dodd, Neil C. Dodge, Paul D. Drew, Rene Drucker Colín, Irena Dujmovic, Marcelo Dutra Arbo, Scott Edwards, Afshar Etemadi-Aleagha, Cuneyt Evren, Juan Fang, Camino Fernández-Rodríguez, Radmila Filipovic, Josef Finsterer, Megan L. Fitzgerald, Manoela V. Fogaça, Diego A. Forero, Hamdy Fouad Moselhy, Marco Antonio de Freitas, Cherrie Galletly, Borja García-Bueno, Jodi M. Gatley, David Germanaud, Roger S. Gifford, Paul Glue, Gabriella Gobbi, Carlos Goicoechea, Emilio González-Arnay, Emilio González-Reimers, Rogelio González-Sarmiento, Linda Gowing, Kenneth L. Grieve, Rubem Carlos Araújo Guedes, Consuelo Guerri, Francisco S. Guimarães, Leila Guller, Jennifer Harland, Seyyed A. Hashemi, Shiva Hashemizadeh, Bei He, Salvador Hernández-López, Tyson Hickle, Shirley Y. Hill, Joan Holgate, Wei Huang, Wei-Lieh Huang, Nicholas J. Hunt, René Hurlemann, Giuseppe Iannone, Fariha Idrees, Jawaria Idrees, Kazutaka Ikeda, Nato Ivanashvili, Iliyan Ivanov, Joseph L. Jacobson, Sandra W. Jacobson, Torbjörn U.C. Järbe, Y.L. Jiang, Farzaneh Jokar, Cynthia J.M. Kane, Megan Kangiser, Victor Karpyak, Jean A. King, Bronwyn M. Kivell, Eugene A. Kiyatkin, Jochen Klein, Michelle L. Klima, Sodikdjon A. Kodirov, Michal Korostynski, Mary Jeanne Kreek, Svetlana Kulevanova, Santosh Kumar, Berthold Langguth, Mirna Bainy Leal, Sheng-Yu Lee, Tatia M.C. Lee, John Leikaif, Shih-Hsien Lin, Yu-Hsuan Lin, Xiu Liu, Valentina Lorenzetti, Ru-Band Lu, Rita Machaalani, Antoniette Maldonado-Devincci, Jean-François Mangin, Dimitra Mangoura, Patrick Manning, Jahan P. Marcu, Simon McCabe, M. Adrienne McGinn, Diana L. McKinney, Ryan McLaughin, Ian McLaughlin, Ernesta Meintjes, Narasimha M. Midde, Stefan Mihailescu, José Miñarro, Raffaella Mondola, A. Leslie Morrow, Nina R. Mota, Jeffrey Newcorn, Daisuke Nishizawa, José N. Nobrega, Christina N. Nona, Nicolas Nuñez, Ingrid Nylander, Jessica W. O’Brien, Francesco Oliva, Sara Palm, Mauricio R. Papini, Byung Lae Park, María Pascual, Juan Pedraza, Giampaolo Perna, Rocco Luigi Picci, Marcin Piechota, Vladimir Pilija, Charles Pinto, Stéphane Potvin, Jagdeo Prasad Rawat, Victor R. Preedy, Brittany M. Priddy, Ryszard Przewlocki, Jimit G. Raghav, Rajkumar Rajendram, Roshanna Rajendram, P.S.S. Rao, Anirban Ray, Ameneh Rezayof, Casto Rivadulla, Marta Rodríguez-Arias, Luciana Grazziotin Rossato, Diego L. Rovaris, Christina L. Ruby, Nikos Sakellaridis, Saad Salman, Francisco Santolaria-Fernández, Siddharth Sarkar, Jason B. Schechter, André Schmidt, Susan Scholl, April Scott, Masroor Shariff, Shiwali Sharma, Hyoung Doo Shin, Thakur Gurjeet Singh, Namita Sinha, Patrick D. Skosnik, Ranilson de Souza Bezerra, Dustin J. Stairs, Gjoshe Stefkov, Dan J. Stein, Cristina A.J. Stern, Claudia Stöllberger, Reinaldo N. Takahashi, H.C. Tang, Josephine Tarren, Philip G. Tibbo, Vinod Tiwari, Carmen Torres, Federica Trivelli, Penelope Truman, Emmanouella Tsirimonaki, Sven Vanneste, Andrea R. Vansickel, Leandro F. Vendruscolo, Maria S.M. Wai, Marc Walter, Karen A. Waters, Jeffrey L. Weiner, Jodi J. Weinstein, Jordyn Weisberg, Annie M. Whitaker, Sarah Wolf-Stanton, Chen-Ying Wu, Sharon L. Wu, Cheryl C.H. Yang, Yen Kuang Yang, Kirti Yeshwant Tandel, D.T. Yew, Yashar Yousefzadeh Fard, Yan Zhou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fcf12b9446119863402c7acf45328e6e
https://doi.org/10.1016/b978-0-12-800213-1.01002-6

Activation of Vav by the Gammaherpesvirus M2 Protein Contributes to the Establishment of Viral Latency in B Lymphocytes

Autor: María J. Caloca, J. Pedro Simas, Marta Pires de Miranda, Xosé R. Bustelo, Lénia Rodrigues

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Gammaherpesviruses subvert eukaryotic signaling pathways to favor latent infections in their cellular reservoirs. To this end, they express proteins that regulate or replace functionally specific signaling proteins of eukaryotic cells. Here we descri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317787ab6ea6483ce5b345479ec97111
https://doi.org/10.1128/jvi.02700-05

Characterization of the Rac-GAP (Rac-GTPase-activating protein) activity of β2-chimaerin, a ‘non-protein kinase C’ phorbol ester receptor

Autor: María J. Caloca, Marcelo G. Kazanietz, HongBin Wang

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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The regulation and function of β2-chimaerin, a novel receptor for the phorbol ester tumour promoters and the second messenger DAG (diacylglycerol), is largely unknown. As with PKC (protein kinase C) isoenzymes, phorbol esters bind to β2-chimaerin w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff385f4f2b091ee6255320f98578a48b
https://doi.org/10.1042/bj20030727