Zobrazeno 1 - 10
of 39
pro vyhledávání: '"María J, Iraburu"'
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1400 (2020)
AGAP2 (Arf GAP with GTP-binding protein-like domain, Ankyrin repeat and PH domain 2) isoform 2 is a protein that belongs to the Arf GAP (GTPase activating protein) protein family. These proteins act as GTPase switches for Arfs, which are Ras superfam
Externí odkaz:
https://doaj.org/article/8e20078d7e744587afe7ea28a18bc942
Autor:
Karol M, Córdoba, Daniel, Jericó, Ana, Sampedro, Lei, Jiang, María J, Iraburu, Paolo G V, Martini, Pedro, Berraondo, Matías A, Avila, Antonio, Fontanellas
Publikováno v:
International review of cell and molecular biology. 372
Inborn errors of metabolism (IEM) encompass a group of monogenic diseases affecting both pediatric and adult populations and currently lack effective treatments. Some IEM such as familial hypercholesterolemia or X-linked protoporphyria are caused by
Autor:
Julen Oyarzabal, Robert Arnes-Benito, Leticia Colyn, Jose J.G. Marin, Jose M Herranz, Maite G. Fernandez-Barrena, María J. Iraburu, Maria Francesconi, Gloria Alvarez-Sola, Meritxell Huch, Leonard J Nelson, Francisco Javier Cubero, Matías A. Avila, Altaf A. Dar, Jesus M. Banales, Iker Uriarte, Mikel Ruiz de Gauna, Simone Carotti, Jesús Urman, Sergio Morini, María L. Martínez-Chantar, Chaobo Chen, Marina Bárcena-Varela, Eva Santamaría, Andrea Casadei-Gardini, Christian Trautwein, Patricia Aspichueta, Alvaro Santos-Laso, Carmen Berasain, Felipe Prosper, Bruno Sangro, John M Patino, Matteo Canale, Mehdi Nosrati, María Arechederra, M. Ujue Latasa
Publikováno v:
Hepatology. 73:2380-2396
Background and aims Cholangiocarcinoma (CCA) is a devastating disease often detected at advanced stages when surgery cannot be performed. Conventional and targeted systemic therapies perform poorly, and therefore effective drugs are urgently needed.
Autor:
Marina Ruiz de Galarreta, Elena Arriazu, María P. Pérez de Obanos, Eduardo Ansorena, María J. Iraburu
Publikováno v:
Journal of Physiology and Biochemistry.
Ocoxin is a nutritional supplement that has been shown to exert antioxidant and immunomodulatory responses in patients with chronic hepatitis C. The present work aimed to determine the effects of Ocoxin on activated hepatic stellate cells (HSC), the
Autor:
Karol M. Córdoba, Daniel Jericó, Ana Sampedro, Lei Jiang, María J. Iraburu, Paolo G.V. Martini, Pedro Berraondo, Matías A. Avila, Antonio Fontanellas
Publikováno v:
mRNA-Based Therapeutics ISBN: 9780323994019
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e4851bb34f980ef00baf94f653f12a6
https://doi.org/10.1016/bs.ircmb.2022.03.005
https://doi.org/10.1016/bs.ircmb.2022.03.005
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 6978, p 6978 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 6978, p 6978 (2021)
The endocytosis of ligand-bound receptors and their eventual recycling to the plasma membrane (PM) are processes that have an influence on signalling activity and therefore on many cell functions, including migration and proliferation. Like other tyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa605bbeca0e59dd6996901509ac5657
https://irep.ntu.ac.uk/id/eprint/43301/1/1448761_Montiel-Duarte.pdf
https://irep.ntu.ac.uk/id/eprint/43301/1/1448761_Montiel-Duarte.pdf
Cholangiocarcinoma (CCA) and pancreatic adenocarcinoma (PDAC) may lead to the development of extrahepatic obstructive cholestasis. However, biliary stenoses can also be caused by benign conditions, and the identification of their etiology still remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3592f1854b3a2cf01568953c5c9985fc
Autor:
Maite G. Fernandez-Barrena, Daniel Oyón, Maria U. Latasa, Marta R. Romero, Isabel Gil, Maria J. Monte, Jose M Herranz, Gloria Alvarez-Sola, Leticia Colyn, María Rullán, Iker Uriarte, Bruno Sangro, Jose J.G. Marin, Matías A. Avila, Lucía Zabalza, F. Bolado, Belén González, Marta Iruarrizaga-Lejarreta, Jesús Urman, María J. Iraburu, María L. Martínez-Chantar, María Arechederra, Francisco Javier Cubero, Ignacio Fernandez-Urien, Jesus M. Banales, Juan Carrascosa, Fernando J. Corrales, Rocio I.R. Macias, Ana Purroy, Cristina Alonso, Carmen Berasain, Leonor Puchades-Carrasco, Juan J. Vila, Lorena Carmona, Antonio Pineda-Lucena
Publikováno v:
E-Prints Complutense. Archivo Institucional de la UCM
instname
Cancers
Volume 12
Issue 6
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Cancers, Vol 12, Iss 1644, p 1644 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cancers
Volume 12
Issue 6
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Cancers, Vol 12, Iss 1644, p 1644 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
Cholangiocarcinoma (CCA) and pancreatic adenocarcinoma (PDAC) may lead to the development of extrahepatic obstructive cholestasis. However, biliary stenoses can also be caused by benign conditions, and the identification of their etiology still remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1e9f85d1b08f3ebb21b6565a8accf8
https://eprints.ucm.es/id/eprint/67496/1/cancers-12-01644-v3.pdf
https://eprints.ucm.es/id/eprint/67496/1/cancers-12-01644-v3.pdf
Autor:
Carmen Berasain, Felipe Prosper, Alex Claveria, Krista Rombouts, Miriam Recalde, Maria U. Latasa, Laura Alvarez, Leticia Colyn, Maite G. Fernandez-Barrena, María J. Iraburu, Malgorzata Milkiewicz, Maria Garate, Hannah L Paish, Eva Santamaría, Ana Pardo-Saganta, Fiona Oakley, Bruno Sangro, Jelena Mann, Iker Uriarte, María Arechederra, Jeremy French, Marina Bárcena-Varela, Julen Oyarzabal, Piotr Milkiewicz, Matías A. Avila, Stuart Robinson
Publikováno v:
Gut. :gutjnl-2019
ObjectiveHepatic stellate cells (HSC) transdifferentiation into myofibroblasts is central to fibrogenesis. Epigenetic mechanisms, including histone and DNA methylation, play a key role in this process. Concerted action between histone and DNA-mehyltr
Autor:
Gloria Alvarez-Sola, Eduardo Ansorena, María J. Iraburu, Matías A. Avila, María J. López-Zabalza, Amaia Navarro-Corcuera, Juan J. Martinez-Irujo, Cristina Montiel-Duarte
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1866(4)
Liver damage induces hepatic stellate cells (HSC) activation, characterised by a fibrogenic, proliferative and migratory phenotype. Activated HSC are mainly regulated by transforming growth factor β 1 (TGFβ1), which increases the production of extr