Zobrazeno 1 - 10
of 14
pro vyhledávání: '"María Isabel Yuseff"'
Autor:
Isidora Riobó, María Isabel Yuseff
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionEngagement of the B-cell receptor with immobilized antigens triggers the formation of an immune synapse (IS), a complex cellular platform where B-cells recruit signaling molecules and reposition lysosomes to promote antigen uptake and pro
Externí odkaz:
https://doaj.org/article/794e569b0abc4df097545ad5b58ffe9b
Dopaminergic stimulation leads B-cell infiltration into the central nervous system upon autoimmunity
Autor:
Carolina Prado, Francisco Osorio-Barrios, Paulina Falcón, Alexandra Espinoza, Juan José Saez, María Isabel Yuseff, Rodrigo Pacheco
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-20 (2021)
Abstract Background Recent evidence has shown dopamine as a major regulator of inflammation. Accordingly, dopaminergic regulation of immune cells plays an important role in the physiopathology of inflammatory disorders. Multiple sclerosis (MS) is an
Externí odkaz:
https://doaj.org/article/d08973e8eedf4a668d9270322c8a2bb1
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Lipid-related disorders, which primarily affect metabolic tissues, including adipose tissue and the liver are associated with alterations in lysosome homeostasis. Obesity is one of the more prevalent diseases, which results in energy imbalance within
Externí odkaz:
https://doaj.org/article/55554431bf4c48668c6c0283c9f489c3
Autor:
Diego Tapia, Tomás Jiménez, Constanza Zamora, Javier Espinoza, Riccardo Rizzo, Alexis González-Cárdenas, Danitza Fuentes, Sergio Hernández, Viviana A. Cavieres, Andrea Soza, Fanny Guzmán, Gloria Arriagada, María Isabel Yuseff, Gonzalo A. Mardones, Patricia V. Burgos, Alberto Luini, Alfonso González, Jorge Cancino
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Inter-organelle signaling coordinates adaptive responses via currently unknown mechanisms. Here, Tapia et al. show that KDEL signaling repositions lysosomes in a complex process termed ‘traffic-induced degradation response for secretion’ (TIDeRS)
Externí odkaz:
https://doaj.org/article/a62da610b52144bab687c355e916d6aa
Autor:
Jorge Ibañez-Vega, Felipe Del Valle, Juan José Sáez, Fanny Guzman, Jheimmy Diaz, Andrea Soza, María Isabel Yuseff
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The formation of an immune synapse (IS) enables B cells to capture membrane-tethered antigens, where cortical actin cytoskeleton remodeling regulates cell spreading and depletion of F-actin at the centrosome promotes the recruitment of lysosomes to f
Externí odkaz:
https://doaj.org/article/c9f4ef65b16c4c22b22a8747231af7f0
Autor:
Muriel Antonieta Núñez, Oreste Corrales, Victoria Velasquez, Daniel Ernst, Montecinos Viviana, Francisco Nualart, María Isabel Yuseff, Javier Cerda-Infante
Publikováno v:
Cancer Research. 83:4640-4640
Introduction: Cancer progression and metastatic spread is modulated by the tumor microenvironment. Cancer-associated fibroblasts (CAF) are the most abundant cell type within the tumor microenvironment. Little is known about the specific mechanisms by
Autor:
Romina Ulloa, Oreste Corrales, Fernanda Cabrera-Reyes, Jorge Jara-Wilde, Juan José Saez, Christopher Rivas, Jonathan Lagos, Steffen Härtel, Clara Quiroga, María-Isabel Yuseff, Jheimmy Diaz-Muñoz
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Upon interaction with immobilized antigens, B cells form an immune synapse where actin remodeling and re-positioning of the microtubule-organizing center (MTOC) together with lysosomes can facilitate antigen extraction. B cells have restricted cytopl
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1988
The ability of B lymphocytes to capture external antigens (Ag) and present them as peptide fragments, loaded on major histocompatibility complex (MHC) class II molecules, to CD4
Publikováno v:
Antigen Processing ISBN: 9781493994496
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cdd36d617ce3f69edaf118c51d29076
https://doi.org/10.1007/978-1-4939-9450-2_29
https://doi.org/10.1007/978-1-4939-9450-2_29
Autor:
María-Paz, Marzolo, María Isabel, Yuseff, Claudio, Retamal, Maribel, Donoso, Fernando, Ezquer, Pamela, Farfán, Yonghe, Li, Guojun, Bu
Publikováno v:
Traffic (Copenhagen, Denmark). 4(4)
Megalin and the low-density lipoprotein (LDL) receptor-related protein (LRP) are two large members of the LDL receptor family that bind and endocytose multiple ligands. The molecular and cellular determinants that dictate the sorting behavior of thes