Zobrazeno 1 - 10
of 50
pro vyhledávání: '"María Isabel, Niemeyer"'
Autor:
Marcelo A. Catalán, Francisca Julio-Kalajzić, María Isabel Niemeyer, Luis Pablo Cid, Francisco V. Sepúlveda
Publikováno v:
Cells, Vol 9, Iss 8, p 1781 (2020)
Lubiprostone, a 20-carbon synthetic fatty acid used for the treatment of constipation, is thought to act through an action on Cl− channel ClC-2. Short chain fatty acids (SCFAs) are produced and absorbed in the distal intestine. We explore whether S
Externí odkaz:
https://doaj.org/article/d3d329f6bb884995b5fe90aa8789a266
Publikováno v:
The Journal of Physiology. 599:593-608
Key points Kir7.1 K+ channel expressed in retinal pigment epithelium is mutated in inherited retinal degeneration diseases. We study Kir7.1 in heterologous expression to test the hypothesis that pathological R162 mutation to neutral amino-acids resul
Autor:
Isabel Cornejo, Olga Andrini, María Isabel Niemeyer, Vanessa Marabolí, F Danilo González-Nilo, Jacques Teulon, Francisco V Sepúlveda, L Pablo Cid
Publikováno v:
PLoS Pathogens, Vol 10, Iss 9, p e1004402 (2014)
Parasitic sea lice represent a major sanitary threat to marine salmonid aquaculture, an industry accounting for 7% of world fish production. Caligus rogercresseyi is the principal sea louse species infesting farmed salmon and trout in the southern he
Externí odkaz:
https://doaj.org/article/9a1e2cafc05646e8a6773295611eeaf3
Publikováno v:
The Journal of physiologyReferences. 599(2)
Kir7.1 KMutations in the Kir7.1 K
Autor:
Leandro Zúñiga, Valeria Márquez, Fernando D González-Nilo, Christophe Chipot, L Pablo Cid, Francisco V Sepúlveda, María Isabel Niemeyer
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16141 (2011)
K(+) channels share common selectivity characteristics but exhibit a wide diversity in how they are gated open. Leak K(2P) K(+) channels TASK-2, TALK-1 and TALK-2 are gated open by extracellular alkalinization. The mechanism for this alkalinization-d
Externí odkaz:
https://doaj.org/article/55ccb5c0112f492ebbbf478c5127f501
Autor:
Francisco V. Sepúlveda, Johanna Burgos, Erwin Vera, L. Pablo Cid, Isabel Cornejo, María Isabel Niemeyer
Publikováno v:
Biochemical and biophysical research communications. 514(3)
Kir7.1 is an inwardly rectifying K+ channel present in epithelia where it shares membrane localization with the Na+/K+-pump. In the present communication we report the presence of a novel splice variant of Kir7.1 in mouse tissues including kidney, lu
Autor:
Francisco V. Sepúlveda, Luis Pablo Cid, Francisca Julio-Kalajzić, Marcelo A. Catalán, María Isabel Niemeyer
Publikováno v:
Cells
Cells, Vol 9, Iss 1781, p 1781 (2020)
Volume 9
Issue 8
Cells, Vol 9, Iss 1781, p 1781 (2020)
Volume 9
Issue 8
Lubiprostone, a 20-carbon synthetic fatty acid used for the treatment of constipation, is thought to act through an action on Cl- channel ClC-2. Short chain fatty acids (SCFAs) are produced and absorbed in the distal intestine. We explore whether SCF
Publikováno v:
PHYSIOLOGICAL REVIEWS
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
K+channels fulfill roles spanning from the control of excitability to the regulation of transepithelial transport. Here we review two groups of K+channels, pH-regulated K2Pchannels and the transport group of Kir channels. After considering advances i
Autor:
María Isabel Niemeyer, Carolina Añazco, Gaspar Peña-Münzenmayer, Francisco V. Sepúlveda, L. Pablo Cid, Carla Araya
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 465:1715-1726
TASK-2 (K2P5.1) is a background K(+) channel opened by extra- or intracellular alkalinisation that plays a role in renal bicarbonate handling, central chemoreception and cell volume regulation. Here, we present results that suggest that TASK-2 is als
Publikováno v:
Scientific Reports
Two-pore domain K2P K+ channels responsible for the background K+ conductance and the resting membrane potential, are also finely regulated by a variety of chemical, physical and physiological stimuli. Hormones and transmitters acting through Gq prot