Výsledky vyhledávání - "María Inés Borelli"

Evidence for the paracrine action of islet-derived corticotropin-like peptides on the regulation of insulin release

Autor: Fernando E. Estivariz, Juan José Gagliardino, María Inés Borelli

Publikováno v: Metabolism. 45:565-570

In view of recent evidence for the endogenous synthesis of proopiomelanocortin (POMC) by pancreatic islets, we have assessed (1) the release of POMC-derived corticotropin (ACTH)-like peptides (ACTH-LP) from isolated perifused rat islets, and (2) the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f469c0f814f717f2b75a383babea2260
https://doi.org/10.1016/s0026-0495(96)90025-6

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Islet neogenesis-associated protein signaling in neonatal pancreatic rat islets: Involvement of the cholinergic pathway

Autor: María Inés Borelli, Shanta J. Persaud, Juan José Gagliardino, Gabriel Forato Anhê, Silvana Bordin, James E. Bowe, Antonio C. Boschero, Helena C. Barbosa

Publikováno v: SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

Islet neogenesis associated protein (INGAP) increases islet mass and insulin secretion in neonatal and adult rat islets. In the present study, we measured the short- and long-term effects of INGAP-PP (a pentadecapeptide having the 104-118 amino acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbeb18d2f21ea4b9d3337a6ad8437d3
http://sedici.unlp.edu.ar/handle/10915/84230

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Decreased islet sensitivity to insulin in hamsters with dietary-induced insulin resistance

Autor: María Inés Borelli, Flavio Francini, Juan José Gagliardino

Publikováno v: Life sciences. 82(15-16)

In the present study, we evaluated the autocrine modulatory effect of insulin on glucose metabolism and glucose-induced insulin secretion in islets isolated from hamsters with insulin resistance (IR) induced by administration of a sucrose-rich diet (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d38be53f9330c97c971fbd795016f2
https://pubmed.ncbi.nlm.nih.gov/18331742

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INGAP-PP up-regulates the expression of genes and proteins related to K+ ATP channels and ameliorates Ca2+ handling in cultured adult rat islets

Autor: Juan José Gagliardino, Hector Herminio del Zotto, Helena C. Barbosa, Antonio C. Boschero, Everardo M. Carneiro, José Roberto Bosqueiro, Alex Rafacho, Kelly Elizeu da Silva, María Inés Borelli, Luiz Fabrizio Stoppiglia

Publikováno v: Regulatory peptides. 148(1-3)

Islet Neogenesis Associated Protein (INGAP) increases pancreatic β-cell mass and potentiates glucose-induced insulin secretion. Here, we investigated the effects of the pentadecapeptide INGAP-PP in adult cultured rat islets upon the expression of pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b598064a7f9db7a8535d46bbce22a54d
https://pubmed.ncbi.nlm.nih.gov/18378016

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Transcription, expression and tissue binding in vivo of INGAP and INGAP-related peptide in normal hamsters

Autor: María Inés Borelli, Luis Emilio Flores, Hector Herminio del Zotto, Antonio C. Boschero, Juan José Gagliardino, M. E. Garcia

Publikováno v: Regulatory peptides. 140(3)

We studied islet neogenesis-associated protein (INGAP) transcription and its immunocytochemical presence in and binding in vivo of (125)I-tyrosylated INGAP pentadecapeptide ((125)I-T-INGAP-PP) to different normal male hamster tissues. (125)I-T-INGAP-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bea037addffe8bd508dc410112c8d9
https://pubmed.ncbi.nlm.nih.gov/17320200

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Autor: María Inés Borelli, Luiz Fabrizio Stoppiglia, Luis Emilio Flores, Luiz F. Rezende, Hector Herminio del Zotto, Juan José Gagliardino, Antonio C. Boschero

Publikováno v: Regulatory peptides. 131(1-3)

We examined the effects of a pentadecapeptide having the 104–118 aminoacid sequence of islet neogenesis-associated protein (INGAP-PP) on insulin secretion, and the morphological characteristics of adult and neonatal pancreatic rat islets cultured i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715966ae447e0e073ecaf4c708d7d2bb
https://pubmed.ncbi.nlm.nih.gov/16084603

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Autocrine regulation of glucose metabolism in pancreatic islets

Autor: Flavio Francini, María Inés Borelli, Juan José Gagliardino

Publikováno v: American journal of physiology. Endocrinology and metabolism. 286(1)

We evaluated the possible autocrine modulatory effect of insulin on glucose metabolism and glucose-induced insulin secretion in islets isolated from normal hamsters. We measured14CO2and3H2O production from d-[U-14C]glucose and d-[5-3H]glucose, respec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2c8066915a6c85ad632740fbbb2bc8
https://pubmed.ncbi.nlm.nih.gov/13129856

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Tyrosine hydroxylase activity in the endocrine pancreas: changes induced by short-term dietary manipulation

Autor: María Inés Borelli, Luis Emilio Flores, Modesto C. Rubio, M. E. Garcia, Juan José Gagliardino

Publikováno v: BMC Endocrine Disorders, Vol 3, Iss 1, p 2 (2003)
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
BMC Endocrine Disorders

Background: Tyrosine hydroxylase (TH) activity and its possible participation in the control of insulin secretion were studied in pancreatic islets of adult Wistar rats fed a standard commercial diet (SD) or carbohydrates alone (CHD) for one week. TH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3cd91f1f7674865633889fa6aac7cc
http://www.biomedcentral.com/1472-6823/3/2

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